NCT07924774Recruiting
Cognitive Rehabilitation of Executive Dysfunction With the Goal Management Training (GMT) - Exploring Variations in Mode of Administration, Frequency and Intensity.
Source: ClinicalTrials.gov · Last updated 9 Nov 2026
Brief summary (registry, in English)
Executive functions help people initiate, organize, monitor, and complete everyday activities. Difficulties with these functions are common after acquired brain injury and may also occur in people with long-term pain. A person may understand what needs to be done but still have difficulty starting an activity, maintaining focus on the overall goal, monitoring performance, adjusting a plan, or completing the activity. These difficulties can affect independence, rehabilitation, work, studies, family life, and participation in society. Goal Management Training is a structured cognitive rehabilitation program designed to help people manage goal-directed activities. Participants learn strategies for stopping ongoing or automatic behavior, identifying the current goal, dividing complex activities into manageable steps, monitoring progress, and redirecting attention when they lose track of the goal. This multicenter study evaluates the implementation and effects of a Swedish version of Goal Management Training in adults with executive difficulties or reduced working memory following acquired brain injury or in association with long-term pain. The program is delivered as part of clinical rehabilitation at participating centers in Sweden. The study examines whether Goal Management Training can be implemented in different rehabilitation settings and delivered in different clinical formats, including group-based, individually delivered, in-person, and remotely delivered treatment. The choice of format is based on the participant's clinical rehabilitation needs and the conditions at the participating center. Specific program formats in terms of intensity (five-, seven-, and nine-session versions of Goal Management Training), may be evaluated in separate analyses within the overall study. Changes are assessed in areas including cognitive functioning, everyday executive difficulties, activity, and participation. The study also examines whether improvements are maintained after the intervention and explores differences in patterns of response between participants and treatment formats. The overall aim is to improve knowledge about how Goal Management Training can be implemented in Swedish rehabilitation services and adapted to different patient groups, clinical settings, and modes of delivery. The findings may contribute to more accessible and individually adapted cognitive rehabilitation for people with acquired brain injury or long-term pain.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 3 Nov 2026
- Start date
- 1 Mar 2022
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- Karolinska Institutet
- Diseases
- Stroke
- NCT number
- NCT07924774
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 1 Mar 2022 to the primary completion date, 31 Dec 2029
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 67 with acquired brain injury or long-term pain who have trouble with planning, focus or working memory. They join a group skills program.
- Age
- 18 to 67 years
- Sex
- All sexes can join
- Disease stage
- Acquired brain injury needing rehabilitation, or referred to the Pain Section at the Regional University Hospital (RUS) for standard pain rehabilitation. Self-reported or test-verified executive dysfunction or working memory problems.
- Earlier treatment
- Must be taking part in team-based rehabilitation at one of the participating sites.
Main reasons for not taking part
- Weak logical reasoning (WAIS Matrices scaled score below 6)
- Severe lack of insight that lowers motivation for the treatment
- Severe memory problems that stop learning and using the strategies
- Not enough Swedish to take part in the program
- Severe psychiatric illness, substance abuse or dependence, heavily sedating medicines, or a progressive neurological disease
Read by machine on 10 Nov 2026.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- 1 a) Acquired brain injury (ABI) with an indicated need for rehabilitation and presenting with self-reported and/or test-verified executive dysfunction or working memory deficits.
- 1 b) Referred to the Pain Section at the Regional University Hospital (RUS) for standard pain rehabilitation and presenting with self-reported and/or test-verified executive dysfunction or working memory deficits.
- Aged between 18 and 67 years. 3. Participating in team-based rehabilitation at one of the participating multicenter sites.
- Provided written informed consent to participate in the study from the patient or a next of kin/legally authorized representative.
- The intervention requires at least moderate illness insight, some awareness of how difficulties manifest in daily life, and adequate memory retention to learn and generalize strategies outside of session. Consequently, the following exclusion criteria apply:
- Impaired fluid/logical reasoning, defined as scoring 1.5 standard deviations (SD) or more below the mean on the WAIS Matrices subtest (scaled score < 6).
- Severe insight deficits that significantly diminish motivation to engage in the treatment.
- Severe memory impairment that prevents the development of clinical insight and the ability to generalize learned strategies.
- Insufficient proficiency in the Swedish language to comprehend and actively participate in the treatment protocol.
- Extensive or severe psychiatric comorbidities that interfere with active participation.
- Substance abuse/dependence, ongoing use of heavily sedating medications, or presence of a progressive neurological disease.
Age in the registry: 18 years to 67 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Garnis Rehabiliteringscenter | Luleå | Sweden | Recruiting |
| Danderyd Hospital | Stockholm | Sweden | Recruiting |
| Östersunds Rehabcentrum | Stockholm | Sweden | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.