Acute myeloid leukemia: open trials in Australia

22 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT07223814
Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
Trial Treatment · Phase 3 · Stichting Hemato-Oncologie voor Volwassenen Nederland
AU-Adelaide-RAH, Adelaide · AU-Adelaide-FLINDERS, Adelaide · AU-Birtinya-SUNSHINECOAST, Birtinya · AU-Brisbane-RBWH, Brisbane · AU-Brisbane-PAH, Brisbane · AU-Camperdown-RPA, Camperdown · AU-Melbourne-PMCC, Melbourne · AU-Melbourne-AUSTIN, Melbourne · AU-Melbourne-MONASH, Melbourne · AU-Sydney-RNSH, Sydney · AU-Sydney-WSAH, Sydney
Registry updated 2026-11-06
NCT06788509
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
Macquarie University Hospital, Macquarie University · The Alfred Hospital, Melbourne · Linear Clinical Research Ltd, Nedlands · Scientia Clinical Research, Randwick
Registry updated 2026-11-04
NCT06852222
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Flinders Medical Centre, Bedford Park · Royal Prince Alfred Hospital, Camperdown · St Vincents Hospital Melbourne, Fitzroy · St George Hospital, Kogarah · Peter MacCallum Cancer Centre, Melbourne · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-11-03
NCT06372717
A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS
Trial Treatment · Phase 1 · Apollo Therapeutics Ltd
Monash Health, Clayton · St Vincent's Hospital Melbourne, Fitzroy · The Alfred Hospital, Melbourne · Hollywood Private Hospital, Nedlands · Royal Perth Hospital, Perth
Registry updated 2026-10-28
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Trial Treatment · Phase 1/2 · AstraZeneca
Fitzroy · Perth
Registry updated 2026-10-23
NCT07211958
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
Trial Treatment · Phase 3 · Syndax Pharmaceuticals
Douglas · Gosford · Kingswood · Kogarah · Melbourne · Nedlands · Parkville · Perth · Randwick · South Brisbane · Wollongong
Registry updated 2026-10-21
NCT07007312
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Trial Treatment · Phase 3 · Kura Oncology, Inc.
Austin Health, Heidelberg · Box Hill Hospital, Heidelberg · Gachon University Gil Medical Center, Kurralta Park · Northern Health Epping, Melbourne · Fiona Stanley Hospital, Murdoch · Calvary Mater Newcastle, Waratah
Registry updated 2026-10-13
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Trial Treatment · Phase 1/2 · Syndax Pharmaceuticals
Alfred Hospital, Melbourne · Peter MacCallum Cancer Centre (PMCC), Melbourne · Sir Charles Gairdner Hospital, Nedlands · Royal Melbourne Hospital (RMH), Parkville · Royal North Shore Hospital, Saint Leonards
Registry updated 2026-10-09
NCT07306832
A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Trial Treatment · Phase 1 · AbbVie
Perth Children'S Hospital /ID# 275673, Perth · The Children's Hospital at Westmead /ID# 275672, Westmead
Registry updated 2026-10-05
NCT04293562
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Trial Treatment · Phase 3 · Children's Oncology Group
Perth Children's Hospital, Perth · Sydney Children's Hospital, Randwick · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-09-17
NCT06824168
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
Trial Treatment · Phase 2 · Daiichi Sankyo
Royal Adelaide Hospital, Adelaide · Austin Health, Australia · St. Vincent's Hospital Melbourne, Darlinghurst · The Alfred Hospital, Melbourne · Royal Perth Hospital, Perth · Gold Coast University Hospital, Southport · Westmead Hospital, Sydney
Registry updated 2026-09-16
NCT04996875
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Trial Treatment · Phase 2 · Cogent Biosciences, Inc.
Nepean Hospital, Kingswood · Peter MacCallum Cancer Centre, Melbourne N. · Gold Coast University Hospital, Southport
Registry updated 2026-09-15
NCT04771130
A Study of BGB-11417 in Participants With Myeloid Malignancies
Trial Treatment · Phase 1/2 · BeOne Medicines
Monash Health, Clayton · Concord Repatriation General Hospital, Concord · St Vincents Hospital Melbourne, Fitzroy · Austin Health, Heidelberg · St George Hospital, Kogarah · The Alfred Hospital, Melbourne · Fiona Stanley Hospital, Murdoch · Linear Clinical Research, Nedlands · One Clinical Research, Nedlands · Orange Health Hospital, Orange · Gold Coast University Hospital, Southport
Registry updated 2026-09-14
NCT06652438
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Trial Treatment · Phase 3 · Stichting Hemato-Oncologie voor Volwassenen Nederland
AU-Adelaide-RAH, Adelaide · AU-Birtinya-SUNSHINECOASTUH General Information, Birtinya · AU-Brisbane-RBWH, Brisbane · AU-Douglas-TOWNSVILLE, Douglas · AU-Melbourne-MONASH, Melbourne · AU-Melbourne-ALFRED, Melbourne · AU-Perth-FSH, Perth · AU-Perth-SCGH, Perth · AU-Sydney-RNSH, Sydney · AU-Sydney-SVSH, Sydney
Registry updated 2026-09-02
NCT04726241
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Trial Treatment · Phase 1/2 · PedAL BCU, LLC
Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-08-25
NCT06656494
ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies
Trial Treatment · Phase 1 · Beijing InnoCare Pharma Tech Co., Ltd.
Royal Perth Hospital, Perth · St Vincent's Hospital, Sydney
Registry updated 2026-08-18
NCT04581512
Study to Evaluate the Safety and Tolerability of EP0042
Trial Treatment · Phase 1/2 · Ellipses Pharma
Royal Perth Hospital, Perth
Registry updated 2026-06-22
NCT05636514
Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS
Trial Treatment · Phase 1 · Clinical Hub for Interventional Research (CHOIR)
Concord Repatriation and General Hospital, Sydney · Nepean Hospital, Sydney · Prince of Wales Hospital, Sydney · Royal Prince Alfred Hospital, Sydney · Westmead Hospital, Westmead
Registry updated 2026-03-18
NCT06366789
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia
Trial Treatment · Phase 1 · Lomond Therapeutics Holdings, Inc.
Eastern Health - Box Hill Hospital, Melbourne · The Alfred Hospital, Melbourne · Linear Clinical Research, LTD, Perth
Registry updated 2025-12-31
NCT06782971
Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX
Research · Clinical Hub for Interventional Research (CHOIR)
Canberra Health Services, Canberra · Royal North Shore Hospital, Sydney · Prince of Wales Hospital, Sydney · Westmead Hospital, Westmead
Registry updated 2025-12-08
NCT03850574
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Trial Treatment · Phase 1/2 · Aptose Biosciences Inc.
Border Medical Oncology, Albury · St Vincent's Hospital Melbourne, Fitzroy · Royal Brisbane and Women's Hospital, Herston · Sir Charles Gairdner Hospital, Nedlands · Townsville University Hospital, Townsville
Registry updated 2025-08-26
NCT05659732
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer
Trial Treatment · Phase 1 · PharmaEngine
Monash Medical Centre, Clayton
Registry updated 2025-07-31

All Acute myeloid leukemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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