ALS (motor neurone disease): open trials in Canada

9 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT07322003
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Trial Treatment · Phase 3 · Prilenia
University of Alberta, Edmonton · McMaster University Medical Centre, Hamilton · Genge Partners, Montreal
Registry updated 2026-10-27
NCT06249867
A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS
Trial Treatment · Phase 2 · Oliver Blanchard
Montreal Neurological Institute, Montreal · Ottawa Hospital Research Institute, Ottawa
Registry updated 2026-10-09
NCT04363684
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Research · Mayo Clinic
University of Toronto, Toronto · University of British Columbia, Vancouver
Registry updated 2026-10-07
NCT06051123
Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients
Trial Treatment · Centre hospitalier de l'Université de Montréal (CHUM)
Stan Cassidy Centre for Rehabilitation, Fredericton · Centre Hospitalier de l'Université de Montréal, Montreal · University of Saskatchewan, Clinical Trials Support Unit, Saskatoon
Registry updated 2026-09-17
NCT07023835
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Trial Treatment · Phase 2 · Zydus Therapeutics Inc.
Zydus 100, Québec · Zydus 101, Toronto
Registry updated 2026-09-01
NCT06665165
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Trial Treatment · Phase 1 · Amylyx Pharmaceuticals Inc.
University Of Calgary, Calgary · McMaster University, Hamilton · London Health Sciences Centre, London · McGill University Health Centre - Centre for Innovative Medicine, Montreal
Registry updated 2026-04-14
NCT05204017
Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS
Research · University of Alberta
University of Alberta, Edmonton · McGill University / Montreal Neurological Institute and Hospital, Montreal · CHU de Quebec -Universite de Laval, Québec · University of Toronto / Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-04-13
NCT07100119
A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis
Trial Treatment · Phase 1 · Eli Lilly and Company
Heritage Medical Research Clinic, Calgary · Walter Mackenzie Health Sciences Centre, Edmonton · London Health Sciences Centre, London · Montreal Neurological Institute and Hospital, Montreal · Sunnybrook Research Institute, Toronto
Registry updated 2026-03-06
NCT05983211
Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2024-09-19

All ALS (motor neurone disease) trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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