Amyloidosis: open trials in Israel

• NCT06128629

  MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

  Trial Treatment · Phase 3 · Intellia Therapeutics

  Rambam Health Care Campus, Haifa · Hadassah University Hospital, Ein Karem, Jerusalem · Sheba medical center, Tel HaShomer

  Registry updated 2026-11-04

• NCT06971380

  Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis

  Trial Treatment · Phase 2 · Polina Stepensky

  Hadassah MO, Jerusalem

  Registry updated 2026-11-04

• NCT07052903

  TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  Trial Treatment · Phase 3 · Alnylam Pharmaceuticals

  Be’er Ya‘aqov · Haifa · Jerusalem · Petah Tikva

  Registry updated 2026-10-20

• NCT07874334

  Phase 1a/b Study of GPRC5D CART Therapy in Relapsed/Refractory Multiple Myeloma and Light-chain Amyloidosis

  Trial Treatment · Phase 1 · Hadassah Medical Organization

  Hadassah MO, Jerusalem

  Registry updated 2026-10-20

• NCT04561518

  ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

  Research · Alnylam Pharmaceuticals

  Jerusalem · Ramat Gan

  Registry updated 2026-10-13

• NCT06768489

  A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

  Trial Treatment · Phase 1 · Janssen Research & Development, LLC

  Carmel Medical Center, Haifa · Hadassah medical Center, Jerusalem · Sheba medical center, Ramat Gan · Tel-Aviv Sourasky Medical Center, Tel Aviv

  Registry updated 2026-09-25

• NCT07789483

  An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of ALXN2220 in Adults With Transthyretin Amyloid Cardiomyopathy

  Trial Treatment · Phase 3 · Alexion Pharmaceuticals, Inc.

  Beer Yaakov · Haifa · Jerusalem · Rehovot

  Registry updated 2026-08-28

• NCT05667493

  An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

  Trial Treatment · Phase 3 · Ionis Pharmaceuticals, Inc.

  Rambam Health Care Campus, Haifa · Hadassah University Hospital - Ein Kerem, Jerusalem · Kaplan Medical Center, Rehovot

  Registry updated 2026-04-17

All Amyloidosis trials and the map

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