Bladder cancer: open trials in United Kingdom

40 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07090499
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Trial Treatment · Phase 1 · Pfizer
Barts Cancer Centre at St. Bartholomew's Hospital; Queen Mary University of London, London · The Christie NHS Foundation Trust, Manchester
Registry updated 2026-11-05
NCT07206225
A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer
Trial Treatment · Phase 1 · Pfizer
Weston Park Cancer Centre, Sheffield · Royal Hallamshire Hospital, Sheffield · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield · The University of Sheffield, Sheffield
Registry updated 2026-11-05
NCT05614739
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
Trial Treatment · Phase 1 · Eli Lilly and Company
The Christie NHS Foundation Trust, Manchester · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield
Registry updated 2026-11-04
NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
St. Bartholomew's Hospital, London · The Christie NHS Foundation Trust, Manchester
Registry updated 2026-11-04
NCT06319820
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Southmead Hospital, Bristol · St Bartholomews Hospital, London · Charing Cross Hospital, London · Newcastle Freeman Hospital, Newcastle upon Tyne · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield · Southampton General Hospital, Southampton · Royal Marsden Hospital, Sutton
Registry updated 2026-11-03
NCT06919965
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Hull University Teaching Hospitals NHS Trust, Cottingham · St Bartholomews Hospital, London · Royal Marsden Hospital, Skerray · Southampton University Hospital, Southampton · Lister Hospital, Stevenage
Registry updated 2026-11-03
NCT07419295
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Cambridge University Hospitals NHS Foundation Trust ( Site 0756), Cambridge · St Bartholomew's Hospital ( Site 0751), London
Registry updated 2026-11-03
NCT07475806
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
Trial Treatment · Phase 2 · Astellas Pharma Global Development, Inc.
Colchester · London · London · Plymouth
Registry updated 2026-11-02
NCT06242470
A Study of MGC026 in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1 · MacroGenics
Oxford University Hospitals NHS Foundation Trust, Oxford · The Royal Marsden NHS Foundation Trust, Sutton
Registry updated 2026-10-28
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Addenbrooke's Hospital, Cambridge · University Hospital Coventry, Coventry · Barts Hospital, London · Royal Free Hospital, London · Nottingham City Hospital Campus, Nottingham
Registry updated 2026-10-26
NCT07186842
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Trial Treatment · Phase 1/2 · BioNTech SE
St James's University Hospital, Leeds · Royal Free Hospital, London · The Christie NHS Foundation Trust, Manchester · Northern Centre for Cancer Research, Newcastle upon Tyne · The Royal Marsden Hospital, Sutton
Registry updated 2026-10-15
NCT07218380
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Trial Treatment · Phase 3 · Eli Lilly and Company
Huddersfield Royal Infirmary, Huddersfield · Royal Marsden Hospital (Chelsea), London · University College London Hospital, London · Royal Marsden Hospital (Sutton), London · St. Bartholomew's Hospital, London · The Christie NHS Foundation Trust, Manchester · Weston Park Hospital, Sheffield
Registry updated 2026-10-07
NCT07232602
KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
St Bartholomew s Hospital ( Site 5206), London
Registry updated 2026-10-02
NCT05176483
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Trial Treatment · Phase 1 · Exelixis
Cambridge · London · Middlesex
Registry updated 2026-10-01
NCT05944237
HTL0039732 in Participants With Advanced Solid Tumours
Trial Treatment · Phase 1/2 · Cancer Research UK
Addenbrooke's Hospital, Cambridge · Velindre Cancer Centre, Cardiff · Ninewells Hospital, Dundee · Clatterbridge Cancer Centre, Liverpool · Guy's Hospital, London · The Christie Hospital, Manchester
Registry updated 2026-10-01
NCT06833073
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Gartnavel General Hospital ( Site 1702), Glasgow · St Bartholomew s Hospital ( Site 1700), London · Torbay Hospital ( Site 1701), Torquay
Registry updated 2026-10-01
NCT05562830
A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 1201), London · St Bartholomew's Hospital ( Site 1206), London
Registry updated 2026-09-28
NCT06253871
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Trial Treatment · Phase 1 · Iambic Therapeutics, Inc
Royal Marsden NHS Foundation Trust, Royal Marsden Hospital (RMH)/Chelsea), Chelsea · Oxford University Hospitals NHS Foundation Trust Churchill Hospital, Oxford · Royal Marsden NHS Foundation Trust, Royal Marsden Hospital (RMH)/Sutton, Sutton
Registry updated 2026-09-09
NCT04104776
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Royal United Hospital, Department of Oncology/Hematology, Bath · Leicester Royal Infirmary, Leicester · Imperial College Healthcare NHS Trust, London · Royal Marsden Hospital - London, London · The Christie NHS Foundation Trust, Department of Medical Oncology, Manchester · Churchill Hospital, Oxford · University Hospital Southampton NHS Foundation Trust, Southampton · Royal Marsden Hospital (Sutton), Sutton · Musgrove Park Hospital, Taunton
Registry updated 2026-08-19
NCT04752722
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
Trial Treatment · Phase 1/2 · enGene, Inc.
The Royal Marsden NHS Foundation Trust, London
Registry updated 2026-08-07
NCT07106762
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Glasgow · Royal Marsden Hospital (Sutton), London · St. Bartholomew's Hospital, London · Sheffield
Registry updated 2026-07-29
NCT05503797
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Trial Treatment · Phase 2 · Fore Biotherapeutics
Sarah Cannon Research Institute, London · The Christie NHS Foundation Trust, Manchester
Registry updated 2026-07-27
NCT04879329
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Trial Treatment · Phase 2 · Seagen, a wholly owned subsidiary of Pfizer
Cambridge University Hospitals NHS Foundation Trust, Cambridge · Beatson West of Scotland Cancer Centre, Glasgow · Barts Health NHS Trust St Bartholomew's Hospital, London · Charing Cross Hospital, London · Guy's Hospital, London · The Christie NHS Foundation Trust, Manchester · The Christie NHS Foundation Trust - Christie Hospital, Manchester · The Clatterbridge Cancer Centre NHS Foundation Trust, The Clatterbridge Cancer Centre - Wirral, Merseyside
Registry updated 2026-07-22
NCT07720284
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
Trial Treatment · Phase 3 · AstraZeneca
Bristol · Cambridge · Preston · Sheffield
Registry updated 2026-07-22
NCT04389632
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Trial Treatment · Phase 1 · Seagen, a wholly owned subsidiary of Pfizer
Queen Elizabeth Hospital, Birmingham · University Hospitals Birmingham NHS Foundation Trust, Birmingham · Sarah Cannon Research Institute, London · The Harley Street Clinic, London · Radiology, London · The Royal Marsden NHS Foundation Trust, London · Diagnostic Centre, London · The Royal Marsden Hospital (Surrey), Sutton · Royal Marsden Hospital, Sutton
Registry updated 2026-07-06

All Bladder cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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