Childhood cancers: open trials in Australia

98 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT05384626
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Trial Treatment · Phase 1/2 · Nuvalent Inc.
Peter MacCallum Cancer Centre, Melbourne · Royal North Shore Hospital, Sydney · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-11-06
NCT05533775
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Perth Children's Hospital, Nedlands · Queensland Children's Hospital, South Brisbane
Registry updated 2026-11-05
NCT04811560
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Trial Treatment · Phase 1/2 · Janssen Research & Development, LLC
Monash Medical Centre, Clayton · Royal Perth Hospital, Perth · Gold Coast University Hospital, Southport
Registry updated 2026-11-04
NCT04924075
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
The Royal Melbourne Hospital (Site 1602), Parkville · Prince of Wales Hospital-Medical Oncology (Site 1601), Randwick
Registry updated 2026-11-03
NCT03435796
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Trial Treatment · Phase 2/3 · Celgene
Royal Prince Alfred Hospital, Camperdown · Peter MacCallum Cancer Centre, Melbourne · The Alfred Hospital, Melbourne · Fiona Stanley Hospital, Murdoch
Registry updated 2026-11-02
NCT06172296
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Trial Treatment · Phase 3 · National Cancer Institute (NCI)
Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Sydney Children's Hospital, Randwick · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-10-30
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Queensland Children's Hospital-Oncology & Haematology (Site 1996), Brisbane · Royal Children's Hospital-Children's Cancer Centre (Site 1994), Melbourne · Sydney Children's Hospital (Site 1997), Randwick
Registry updated 2026-10-30
NCT07630974
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
The Royal Children's Hospital (Site 4994), Parkville · Sydney Children's Hospital-Kids Cancer Centre (Site 4997), Randwick
Registry updated 2026-10-30
NCT07297979
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
Trial Treatment · Phase 1 · Amgen
Chris Obrien Lifehouse, Camperdown · Peter MacCallum Cancer Centre, Melbourne · Perth Childrens Hospital, Nedlands
Registry updated 2026-10-29
NCT06124157
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
John Hunter Children's Hospital, Hunter Regional Mail Centre · Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane
Registry updated 2026-10-27
NCT06838676
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
Trial Treatment · Phase 2 · Nationwide Children's Hospital
Royal Children's Hospital, Melbourne · Perth Children's Hospital, Perth · Sydney Children's Hospital, Randwick · Queensland Children's Hospital, South Brisbane
Registry updated 2026-10-23
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Trial Treatment · Phase 1/2 · AstraZeneca
Fitzroy · Perth
Registry updated 2026-10-23
NCT07211958
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
Trial Treatment · Phase 3 · Syndax Pharmaceuticals
Douglas · Gosford · Kingswood · Kogarah · Melbourne · Nedlands · Parkville · Perth · Randwick · South Brisbane · Wollongong
Registry updated 2026-10-21
NCT03394365
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
Trial Treatment · Phase 3 · Pierre Fabre Medicament
Royal Adelaide Hospital (Adults only), Adelaide · The Prince Charles Hospital (Adults only), Chermside · The Royal Children's Hospital Melbourne (Pediatrics only), Melbourne · Fiona Stanley Hospital (Adults only), Murdoch · The Children's Hospital at Westmead (Pediatrics only), Westmead · Westmead Hospital (Adults only), Westmead
Registry updated 2026-10-19
NCT05327894
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Trial Treatment · Phase 3 · Princess Maxima Center for Pediatric Oncology
North Adelaide- Womens and Childrens Hospital, Adelaide · Australian and New Zealand Children's Haematology/Oncology Group, Clayton · Monash Children's Hosptial, Clayton · New Lambton Heights- John Hunter Children's Hospital, New Lambton Heights · Royal Children's Hospital (Children's Cancer Centre), Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane · Sydney Childrens Hospital, Sydney · The Childrens Hospital At Westmead, Westmead
Registry updated 2026-10-19
NCT06894810
Investigating the Efficacy of a Paediatric Fertility Preservation Decision Aid in Parents and Adolescents and Young Adults (CAYA) Cancer Survivors
Trial Treatment · Murdoch Childrens Research Institute
Murdoch Children's Research Institute, Melbourne
Registry updated 2026-10-16
NCT07109219
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Trial Treatment · Phase 1/2 · AstraZeneca
Melbourne
Registry updated 2026-10-15
NCT07354074
Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Brisbane · North Adelaide
Registry updated 2026-10-15
NCT07387926
Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Sydney
Registry updated 2026-10-15
NCT06064097
A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
John Hunter Children's Hospital, Hunter Regional Mail Centre
Registry updated 2026-10-14
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 1/2 · AstraZeneca
Melbourne
Registry updated 2026-10-13
NCT06137144
AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.
Trial Treatment · Phase 1/2 · AstraZeneca
Adelaide · Birtinya · Fitzroy · Nedlands · South Brisbane · Waratah
Registry updated 2026-10-13
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Trial Treatment · Phase 1/2 · Syndax Pharmaceuticals
Alfred Hospital, Melbourne · Peter MacCallum Cancer Centre (PMCC), Melbourne · Sir Charles Gairdner Hospital, Nedlands · Royal Melbourne Hospital (RMH), Parkville · Royal North Shore Hospital, Saint Leonards
Registry updated 2026-10-09
NCT06697301
Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Southern Adelaide Local Health Network Incorporated Flinders Medical Centre, Bedford Park · Eastern Health, Box Hill · Icon Cancer Centre Chermside, Chermside · Peninsula and South Eastern Haematology and Oncology Group, Frankston · Cancer Care Wollongong, Wollongong
Registry updated 2026-10-06
NCT06941272
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Queensland Children's Hospital (Site 3996), Brisbane · Royal Children's Hospital (Site 3994), Parkville · Sydney Children's Hospital-Kids Cancer Centre (Site 3997), Sydney
Registry updated 2026-10-06

All Childhood cancers trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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