Chronic lymphocytic leukaemia: open trials in Argentina

• NCT05947851

  A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Centro Medico Fleischer (Site 1006), Buenos Aires · Hospital Aleman-oncohematologic diseases (Site 1001), Buenos Aires · Centro de Educación Médica e Investigaciones Clínicas (CEMIC)-Hematology (Site 1002), Buenos Aires · Instituto Alexander Fleming (Site 1005), Ciudad Autónoma de Buenos Aires · Instituto de Investigaciones Clínicas Mar del Plata (Site 1007), Mar del Plata · Sanatorio Parque (Site 1003), Rosario

  Registry updated 2026-11-06

• NCT04728893

  Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

  Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC

  Centro de Educación Médica e Investigaciones Clínicas (CEMIC) (Site 0103), Buenos Aires · FUNDALEU (Site 0104), Caba · Hospital Aleman (Site 0102), Ciudad Autonoma de Buenos Aires · Hospital Privado Universitario de Córdoba (Site 0107), Córdoba · Fundacion Centro Oncologico de Integración Regional-Medical Oncology (Site 0110), Mendoza · Fundacion Estudios Clinicos (Site 0112), Rosario

  Registry updated 2026-10-27

• NCT06943872

  A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

  Trial Treatment · Phase 3 · BeOne Medicines

  Hospital Alemán, CABA · FUNDALEU, CABA · Instituto Alexander Fleming (Iaf), Ciudad Autonoma Buenos Aires

  Registry updated 2026-10-23

• NCT06846671

  A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

  Trial Treatment · Phase 3 · BeOne Medicines

  Hospital Alemán, CABA · FUNDALEU, CABA · CEMIC, CABA · Instituto Alexander Fleming (Iaf), Ciudad Autonoma Buenos Aires · Hospital Italiano de Buenos Aires, Ciudad Autonoma Buenos Aires · Cice 9 de Julio Sanatorio 9 de Julio, San Miguel de Tucumán

  Registry updated 2026-09-28

• NCT06973187

  A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  Trial Treatment · Phase 3 · BeOne Medicines

  FUNDALEU, CABA · Sanatorio Allende, Córdoba · Centro Oncologico de Integracion Regional (Coir), Mendoza · Hospital Privado de Rosario, Rosario

  Registry updated 2026-09-28

• NCT05254743

  A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

  Trial Treatment · Phase 3 · Loxo Oncology, Inc.

  Alexander Fleming, Ciudad Autónoma de Buenos Aire · Hospital Privado de Comunidad, Mar del Plata · Clínica de Nefrología, Urología y Enfermedades Cardiovasculares, Santa Fe

  Registry updated 2026-08-17

All Chronic lymphocytic leukaemia trials and the map

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