Colorectal cancer: open trials in Japan

47 open trials have a site in Japan. Registry data; only the trial team decides who can take part.

NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Trial Treatment · Phase 1/2 · Boehringer Ingelheim
Aichi Cancer Center Hospital, Aichi, Nagoya · Tokai University Hospital, Isehara · Hakuaikai Sagara Hospital, Kagoshima · Kanagawa Cancer Center, Kanagawa, Yokohama · National Cancer Center Hospital East, Kashiwa-shi · Kyoto University Hospital, Kyoto · Osaka International Cancer Institute, Osaka · Japanese Foundation for Cancer Research, Tokyo, Koto-ku
Registry updated 2026-11-05
NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Summit Therapeutics
Aichi · Chiba · Ehime · Fukuoka · Gifu · Hiroshima · Hokkaido · Kawasaki · Osaka · Saitama · Sendai · Shizuoka · Tokyo · Toyama · Yokohama
Registry updated 2026-11-05
NCT07549412
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
Trial Treatment · Phase 3 · EMD Serono Research & Development Institute, Inc.
National Cancer Center Hospital, Chūōku · NHO Kyushu Cancer Center - 300175822, Fukuoka · Saitama Cancer Center - 300175812, Kitaadachi-gun · Cancer Institute Hospital of JFCR, Kōtoku · Aichi Cancer Center Hospital, Nagoya · Osaka International Cancer Institute, Osaka · Kindai University Hospital, Sakai-shi · Shizuoka Cancer Center, Sunto · Kanagawa Cancer Center - Dept of Gastroenterology, Yokohama
Registry updated 2026-11-05
NCT06400472
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
Shizuoka Cancer Center, Shizuoka · National Cancer Center Hospital, Tokyo · Cancer Institute Hospital of JFCR, Tokyo
Registry updated 2026-11-04
NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 2 · Bayer
National Cancer Center Hospital, Chuo Ku · National Cancer Center Hospital East (NCCHE) - Kashiwa Campus, Kashiwa · The Cancer Institute Hospital of JFCR, Koto-ku · Aichi Cancer Center Hospital, Nagoya · Kindai University Hospital, Sakai · Hokkaido University Hospital, Sapporo
Registry updated 2026-11-04
NCT06997497
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Nippon Medical School Hospital (Site 0859), Bunkyo · Chiba Cancer Center (Site 0858), Chiba · National Cancer Center Hospital (Site 0850), Chūō · Kyushu University Hospital (Site 0862), Fukuoka · Saitama Medical University International Medical Center (Site 0860), Hidaka · National Cancer Center Hospital East (Site 0851), Kashiwa · Saitama Prefectural Cancer Center (Site 0857), Kitaadachi-gun · Kagawa University Hospital (Site 0861), Kita-gun · Cancer Institute Hospital of JFCR (Site 0863), Koto · Aichi Cancer Center (Site 0855), Nagoya · Osaka Prefectural Hospital Organization Osaka International Cancer Institute (Site 0852), Osaka · Kindai University Hospital (Site 0854), Sakai · Teine Keijinkai Hospital (Site 0864), Sapporo · Tohoku University Hospital (Site 0853), Sendai · Shizuoka Cancer Center (Site 0856), Sunto-gun · Kanagawa Cancer Center (Site 0865), Yokohama
Registry updated 2026-11-04
NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Trial Treatment · Phase 1 · Eli Lilly and Company
National Cancer Center Hospital East, Chiba · Kyoto University Hospital, Kyoto · The University of Osaka Hospital, Osaka
Registry updated 2026-11-04
NCT07213791
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
National Cancer Center Hospital East, Chiba · Kyoto University Hospital, Kyoto
Registry updated 2026-11-04
NCT06662786
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Chiba Cancer Center, Chiba · National Cancer Center Hospital, Chūōku · National Cancer Center Hospital East, Kashiwa · Aichi Cancer Center, Nagoya · Osaka International Cancer Institute, Osaka · National Hospital Organization Osaka National Hospital, Osaka · Shizuoka Cancer Center, Shizuoka · The University of Osaka Hospital, Suita · The Cancer Institute Hospital of JFCR, Tokyo
Registry updated 2026-11-03
NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Chiba Cancer Center, Chiba · National Cancer Center Hospital, Chūōku · National Cancer Center Hospital East, Kashiwa · Aichi Cancer Center, Nagoya · Osaka International Cancer Institute, Osaka · National Hospital Organization Osaka National Hospital, Osaka · Kindai University Hospital, Sakai · Shizuoka Cancer Center, Shizuoka · The University of Osaka Hospital, Suita · The Cancer Institute Hospital of JFCR, Tokyo
Registry updated 2026-11-03
NCT07284849
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Trial Treatment · Phase 3 · Incyte Corporation
Hyogo Cancer Center, Akashi-shi · Chiba Cancer Center, Chiba · National Cancer Center Hospital, Chūōku · NHO Kyushu Cancer Center, Fukuoka · Saitama Medical University International Medical Center, Hidaka-shi · National Cancer Center Hospital East, Kashiwa-shi · St. Marianna University Hospital, Kawasaki-shi · Saitama Cancer Center, Kitaadachi-gun · Kagawa University Hospital, Kita-gun · Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe · Cancer Institute Hospital of JFCR, Kōtoku · Kurashiki Central Hospital, Kurashiki-shi · Kochi Medical School Hospital, Nankoku-shi · Osaka International Cancer Institute, Osaka · Shizuoka Cancer Center, Shizuoka · The University of Osaka Hospital, Suita-shi · Kanagawa Cancer Center, Yokohama
Registry updated 2026-10-30
NCT06428409
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
National Cancer Center Hospital East (Site 0121), Kashiwa · Kanagawa Cancer Center (Site 0122), Yokohama
Registry updated 2026-10-29
NCT07094204
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Trial Treatment · Phase 1 · Astellas Pharma Inc
Kansai Medical University Hospital, Hirakata · Cancer Institute Hospital of JFCR, Koto-Ku
Registry updated 2026-10-29
NCT04557449
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Trial Treatment · Phase 1/2 · Pfizer
National Cancer Center Hospital East, Kashiwa
Registry updated 2026-10-28
NCT06820463
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Trial Treatment · Phase 2 · AbbVie
National Cancer Center Hospital /ID# 270112, Chuo-Ku · National Cancer Center Hospital East /ID# 270114, Kashiwa-shi · St Marianna University School Of Medicine /ID# 270111, Kawasaki-shi · Aichi Cancer Center /ID# 270113, Nagoya · Tohoku University Hospital /ID# 270966, Sendai
Registry updated 2026-10-27
NCT06330064
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Trial Treatment · Phase 1/2 · Daiichi Sankyo
National Cancer Center Hospital, Chuo Ku · National Cancer Center Hospital East, Kashiwa · The Cancer Institute Hospital of JFCR, Koto-ku · National Hospital Organization Shikoku Cancer Center, Matsuyama · Shizuoka Cancer Center, Nagaizumi-chō · Aichi Cancer Center Hospital, Nagoya · Kindai University Hospital, Ōsaka-sayama · Saitama Cancer Center, Saitama
Registry updated 2026-10-26
NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Chiba Cancer Center, Chiba · National Cancer Center Hospital, Chuo Ku · National Hospital Organization Kyushu Cancer Center, Fukuoka · Saitama Medical University International Medical Center, Hidaka · Saitama Prefectural Cancer Center, Ina-machi · National Cancer Center Hospital East, Kashiwa · Kobe City Medical Center General Hospital, Kobe · The Cancer Institute Hospital of JFCR, Koto-ku · Kurashiki Central Hospital, Kurashiki · National Hospital Organization Shikoku Cancer Center, Matsuyama · Shizuoka Cancer Center, Nagaizumi-cho,Sunto-gun · Aichi Cancer Center Hospital, Nagoya · Osaka International Cancer Institute, Osaka · Hokkaido University Hospital, Sapporo · Tohoku University Hospital, Sendai · The University of Osaka Hospital, Suita · Osaka Medical and Pharmaceutical University Hospital, Takatsuki · Fujita Health University, Toyoake · Yamagata University Hospital, Yamagata · Kanagawa Cancer Center, Yokohama
Registry updated 2026-10-23
NCT07377487
TheraSphere Japan Pre-Market Study
Trial Treatment · Boston Scientific Corporation
National Cancer Center Hospital, Chuo Ku · Kanazawa University Hospital, Kanazawa · Nara Medical University Hospital, Kashihara · Hyogo College of Medicine Hospital, Nishinomiya · Kindai University Hospital, Sayama
Registry updated 2026-10-21
NCT06885034
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Trial Treatment · Phase 1/2 · GlaxoSmithKline
Aichi · Chiba · Hokkaido · Osaka · Tokyo
Registry updated 2026-10-19
NCT07525206
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · AbbVie
National Cancer Center Hospital East /ID# 279917, Kashiwa-shi · St Marianna University School Of Medicine /ID# 279902, Kawasaki-shi · Kobe City Medical Center General Hospital /ID# 280233, Kobe · The Cancer Institute Hospital Of Japanese Foundation for Cancer Research /ID# 282329, Koto-ku · National Hospital Organization Shikoku Cancer Center /ID# 280224, Matsuyama · Osaka International Cancer Institute /ID# 281810, Osaka
Registry updated 2026-10-19
NCT05786924
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Trial Treatment · Phase 1/2 · Institut de Recherches Internationales Servier
Kanagawa Cancer Center, Kanagawa · Kyoto University Hospital, Kyoto · National Cancer Center Hospital, Tokyo
Registry updated 2026-10-13
NCT07023289
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Trial Treatment · Phase 2 · AbbVie
Kyushu University Hospital /ID# 273710, Fukuoka · Gifu University Hospital /ID# 274179, Gifu · National Cancer Center Hospital East /ID# 273614, Kashiwa-shi · Aichi Cancer Center /ID# 275479, Nagoya · National Hospital Organization Osaka National Hospital /ID# 274306, Osaka · Tohoku University Hospital /ID# 275481, Sendai · Shizuoka Cancer Center /ID# 275480, Sunto-gun · Yokohama City University Medical Center /ID# 273657, Yokohama
Registry updated 2026-10-09
NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Pfizer
Chiba Cancer Center, Chiba · Kyushu University Hospital, Fukuoka · Saitama Medical University International Medical Center, Hidaka · National Cancer Center Hospital East, Kashiwa · Saitama Prefectural Cancer Center, Kitaadachi-Gun · The Cancer Institute Hospital of JFCR, Koto-ku · Shizuoka Cancer Center, Nagaizumi-chō · Aichi Cancer Center Hospital, Nagoya · Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka · National Hospital Organization Osaka Medical Center, Osaka · Kanagawa Cancer Center, Yokohama
Registry updated 2026-10-08
NCT05489211
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Trial Treatment · Phase 2 · AstraZeneca
Chūōku · Kashiwa · Kōtoku · Nagoya · Shinagawa-ku · Suita-shi
Registry updated 2026-09-23
NCT07488676
A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
Trial Treatment · Phase 1/2 · Astellas Pharma Global Development, Inc.
National Cancer Center Hospital, Chuo Ku · National Cancer Center Hospital East, Kashiwa-shi · The Cancer Institute Hospital of JFCR, Koto-ku
Registry updated 2026-09-22

All Colorectal cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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