Depression: open trials in United Kingdom

21 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07412756
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Trial Treatment · Phase 3 · Eli Lilly and Company
Edinburgh Royal Infirmary, Edinburgh · Devon Partnership Trust, Exeter · Queen Elizabeth University Hospital, Glasgow · The Maudsley Hospital, London · Clerkenwell Health - London - Welbeck Street, London · Queen's Medical Centre, Nottingham University Hospitals, Nottingham · St Bartholomew's Medical Centre, Oxford · Warneford Hospital, Oxford · Atlantic Medical, Penzance · Woodstock Bower Surgery, Rotherham
Registry updated 2026-11-04
NCT07694076
Mechanisms of Repeated Real-time Biofeedback With 7-Tesla MRI in Depression
Trial Treatment · University of Oxford
Oxford Centre for Integrative Neuroimaging (OxCIN) FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford
Registry updated 2026-11-03
NCT07775300
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
Trial Treatment · Phase 3 · Eli Lilly and Company
Bodmin Community Hospital, Bodmin · Edinburgh Royal Infirmary, Edinburgh · Devon Partnership Trust, Exeter · Queen Elizabeth University Hospital, Glasgow · Avrin - Liverpool, Liverpool · Neuroclnx, Motherwell · St Bartholomew's Medical Centre, Oxford · Atlantic Medical, Penzance · Ascend Clinical Research, Reading · Woodstock Bower Surgery, Rotherham
Registry updated 2026-11-03
NCT06793397
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Trial Treatment · Phase 3 · Cybin IRL Limited
Cambridge University Hospital NHS, Cambridge · Clerkenwell Health - Doncaster, Doncaster · NHS Research Scotland, Edinburgh · Queen Elizabeth University Hospital, Glasgow · Royal Liverpool Hospital, Liverpool · Clerkenwell Health - Welbeck Street, London · RE:Cognition Health, London · Clerkenwell Health - Baker Street, London · King's College London, London · St Pancras Clinical Research, London · Edwardson Building - Campus for Ageing and Vitality, Newcastle upon Tyne · Ascend Clinical Research, Reading · Sheffield Health and Social care NHS Foundation Trust, Sheffield
Registry updated 2026-11-02
NCT06966401
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Trial Treatment · Phase 3 · Neurocrine Biosciences
London · Manchester · Sheffield · Southampton
Registry updated 2026-11-02
NCT07553637
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Trial Treatment · Phase 2 · Alto Neuroscience
Antrim · Birmingham · Bristol · Cardiff · Exeter · London · Nottingham · Oxford · Prescot · Sheffield
Registry updated 2026-10-26
NCT07879924
Dual Neuromodulation for Depression: Boosting TMS With tES
Trial Treatment · Mersey Care NHS Trust
Mersey Care Mood Clinic at Knowsley Resource and Recovery Centre, Liverpool
Registry updated 2026-10-19
NCT07796295
Prescribing the Right Agent for Depression in Adults
Trial Treatment · University of Oxford
NIHR Clinical Research Facility Oxford Health, Oxford
Registry updated 2026-10-09
NCT07300969
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Trial Treatment · Phase 2 · Draig Therapeutics Ltd
Chester · Eastbourne · Glasgow · London · Nottingham · Oxford
Registry updated 2026-10-08
NCT07848477
PROMOTE: Effects of 5-HT4 Agonism on Cognition and Sleep in Peopl With Low Mood
Trial Treatment · University of Oxford
Warneford Hospital, Oxford
Registry updated 2026-10-06
NCT07807930
Individual Narratives of Stimulation (ECT and TMS)
Research · University of Nottingham
Mersey Care NHS Foundation Trust, Liverpool · University of Nottingham, Nottingham
Registry updated 2026-09-30
NCT03320304
A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression.
Research · LivaNova
Glenfield Hospital, Leicester · King's College London, London · Academic Psychiatry Wolfson Research Centre, Newcastle upon Tyne · Mendip HTT / St Andrew's Ward, Wells
Registry updated 2026-08-27
NCT05660642
An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression
Trial Treatment · Phase 2 · Beckley Psytech Limited
MAC Clinical Research, Liverpool · King's College London, Clinical Trials Facility, London · Hammersmith Medicines Research, London
Registry updated 2026-07-06
NCT07651293
Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression
Trial Treatment · Imperial College Healthcare NHS Trust
entre for Psychedelics Research, Division of Psychiatry Imperial College London, Level 2, Commonwealth Building, Hammersmith Campus, Du Cane Road, London, London
Registry updated 2026-06-16
NCT07424781
Fluoxetine on Emotional Experience (FLEX) Study
Trial Treatment · University of Oxford
Department of Psychiatry, University of Oxford, Oxford
Registry updated 2026-02-20
NCT07228468
Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME)
Trial Treatment · King's College London
Cardiff and Vale Health Board, Cardiff · South London and Maudsley NHS Foundation Trust, London · Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle · Northamptonshire Healthcare NHS Foundation Trust, Northampton · Nottinghamshire Healthcare NHS Foundation Trust, Nottingham · Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton
Registry updated 2026-01-26
NCT06537921
Comorbid Obesity and Depression With an Anti-inflammatory Medication
Trial Treatment · King's College London
King's College London, London
Registry updated 2025-11-14
NCT07189689
Mental Health Mission Mood Disorder Cohort Study
Research · University of Oxford
Clinical Research Facility, Warneford Hospital, Oxford
Registry updated 2025-10-03
NCT06823492
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
Research · University of Manchester
Faculty of Biology Medicine & Health, University of Manchester, Manchester
Registry updated 2025-02-12
NCT06801925
Evaluating the Effectiveness and Acceptability of a GPT-4o and RAG-Based Voice Chatbot for Depression Screening Using PHQ-9
Research · University College, London
UCL Institute of Health Informatics, London
Registry updated 2025-01-30
NCT06470035
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)
Trial Treatment · Neurovalens Ltd.
Biomedical Science Research University of Ulster, Coleraine, Belfast
Registry updated 2024-08-09

All Depression trials and the map

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