Diffuse large B-cell lymphoma: open trials in Australia

20 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT06091865
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Trial Treatment · Phase 3 · Regeneron Pharmaceuticals
ICON Cancer Centre Wesley, Auchenflower · Pindara Private Hospital, Benowa · Epworth Freemasons, East Melbourne · Liverpool Hospital, Liverpool · Calvary Mater Newcastle, Waratah
Registry updated 2026-11-04
NCT07188558
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Trial Treatment · Phase 3 · Lyell Immunopharma, Inc.
Townsville University Hospital, Douglas · The Alfred, Melbourne
Registry updated 2026-11-04
NCT05139017
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Grampians Health ( Site 1802), Ballarat · Royal Perth Hospital-Haematology ( Site 1801), Perth · Townsville University Hospital ( Site 1800), Townsville
Registry updated 2026-11-03
NCT05365659
IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas
Trial Treatment · Phase 1 · Iksuda Therapeutics Ltd.
Royal Adelaide Hospital, Adelaide · Royal Hobart Hospital, Hobart · Linear Clinical Research, Perth · Westmead Hospital, Westmead
Registry updated 2026-11-03
NCT07691606
A Study of ARC-02 in B-cell NHL
Trial Treatment · Phase 1 · Taiho Oncology, Inc.
Monash Health, Clayton · Austin Health, Melbourne · Linear Clinical Research, Nedlands · Gold Coast Hospital, Southport
Registry updated 2026-11-02
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Queensland Children's Hospital-Oncology & Haematology ( Site 1996), Brisbane · Royal Children's Hospital-Children's Cancer Centre ( Site 1994), Melbourne · Sydney Children's Hospital ( Site 1997), Randwick
Registry updated 2026-10-30
NCT06500273
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Trial Treatment · Phase 2 · Allogene Therapeutics
ICON Cancer Centre Wesley, Auchenflower · Monash Health, Clayton · St Vincent's Hospital Melbourne, Fitzroy · Austin Health, Heidelberg · Royal Hobart Hospital, Hobart · Hollywood Private Hospital, Nedlands · Calvary Mater Newcastle, Waratah
Registry updated 2026-10-30
NCT07249905
Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma
Trial Treatment · Phase 1/2 · ModeX Therapeutics, An OPKO Health Company
Linear Clinical Research, Nedlands · Epworth Healthcare, Richmond
Registry updated 2026-10-28
NCT06717347
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Royal Adelaide Hospital ( Site 3001), Adelaide · Grampians Health ( Site 3003), Ballarat · Northern Hospital ( Site 3002), Melbourne · Royal Perth Hospital-Haematology ( Site 3004), Perth · Townsville University Hospital ( Site 3006), Townsville
Registry updated 2026-10-21
NCT06806033
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
Trial Treatment · Phase 2 · Hoffmann-La Roche
Epworth Hospital, East Melbourne
Registry updated 2026-10-09
NCT07195916
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
Trial Treatment · Phase 1 · Incyte Corporation
Cancer Research SA, Adelaide · Peter MacCallum Cancer Centre, Royal Melbourne Hospital, Melbourne · Macquarie University Hospital, Sydney · Princess Alexandra Hospital Australia, Woolloongabba
Registry updated 2026-10-09
NCT05006716
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
Trial Treatment · Phase 1/2 · BeOne Medicines
Concord Repatriation General Hospital, Concord · St Vincents Hospital Melbourne, Fitzroy · Austin Health, Heidelberg · Peter MacCallum Cancer Centre, Melbourne · The Alfred Hospital, Melbourne · Linear Clinical Research, Nedlands · Calvary Mater Newcastle, Waratah · Perth Blood Institute, West Perth · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-10-05
NCT05826535
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Trial Treatment · Phase 1/2 · Lyell Immunopharma, Inc.
The Alfred Hospital, Melbourne · Sir Charles Gairdner Hospital, Nedlands · Royal Perth Hospital, Perth
Registry updated 2026-08-25
NCT07634289
Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse Large B Cell Lymphoma
Trial Treatment · Phase 2 · Olivia Newton-John Cancer Research Institute
Flinders Medical Centre, Bedford Park · Townsville University Hospital, Douglas · Austin Hospital, Heidelberg · Fiona Stanley Hospital, Murdoch · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-06-08
NCT06830759
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Research · AbbVie
Nepean Cancer Centre, Nepean Hospital /ID# 277782, Kingswood · Cabrini Hospital Malvern /ID# 277780, Malvern · Calvary Mater Newcastle /ID# 277783, Waratah
Registry updated 2026-02-17
NCT06022029
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Trial Treatment · Phase 1 · OncoNano Medicine, Inc.
Southern Oncology Clinical Research Unit, Bedford Park · University of the Sunshine Coast Clinical Trials, Buderim · St Vincent's Hospital, Darlinghurst · Tasman Oncology Research, Southport · St. John of God Subiaco Hospital, Subiaco · Cancer Care Wollongong, Wollongong · Princess Alexandra Hospital | Metro South Health, Woolloongabba
Registry updated 2025-12-24
NCT04332822
A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma
Trial Treatment · Phase 3 · Nordic Lymphoma Group
Border Medical Oncology Research Unit, Albury · Royal Prince Alfred Hospital, Camperdown · Coffs Harbour, Coffs Harbour · Concord Repatriation General Hospital, Concord · Tweed Valley Hospital, Cudgen · The Canberra Hospital, Garran · Royal Hobart Hospital, Hobart · Liverpool, Liverpool · Western Health, Melbourne · Northern Health, Melbourne · Bendigo, Melbourne · St Vincent's Hospital Melbourne, Melbourne · Fiona Stanley Hospital, Murdoch · Orange Health, Orange · Royal Perth Hospital, Perth · Port Macquarie, Port Macquarie · Prince of Wales Hospital, Randwick · Royal North Shore Hospital, St Leonards · Sunshine Coast University Hospital, Sunshine Coast · Calvary Mater Newcastle, Waratah · Westmead, Westmead
Registry updated 2024-09-19
NCT06287398
Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL
Trial Treatment · Phase 2 · Australasian Leukaemia and Lymphoma Group
Australasian Leukemia and Lymphoma Group, Melbourne
Registry updated 2024-07-22
NCT04920617
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Trial Treatment · Phase 2 · ImmunoVaccine Technologies, Inc. (IMV Inc.)
Royal Adelaide Hospital, Adelaide · Box Hill Hospital, Melbourne · Epworth Freemasons Hospital, Melbourne · Westmead Hospital, Westmead
Registry updated 2023-04-07
NCT04502394
Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL
Trial Treatment · Phase 1/2 · Kartos Therapeutics, Inc.
Royal Adelaide Hospital, Adelaide · Eastern Health - Box Hill Hospital, Box Hill · Barwon Health, Geelong · Royal Perth Hospital, Perth
Registry updated 2022-08-04

All Diffuse large B-cell lymphoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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