Diffuse large B-cell lymphoma: open trials in Brazil

• NCT06091865

  A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

  Trial Treatment · Phase 3 · Regeneron Pharmaceuticals

  Fundacao Pio XII - Hospital de Amor, Barretos · Instituto Mario Penna de Ensino Pesquisa e Inovacao, Belo Horizonte · Instituto Tacchini de Pesquisa em Saude, Bento Gonçalves · Hospital Sirio Libanes Brasilia, Brasília · UOPECCAN - Hospital do Câncer de Cascavel, Cascavel · Hospital Erasto Gaertner, Curitiba · Amaral Carvalho Hospital, Jaú · Centro de Hematologia e Oncologia, Joinville · Animi Unidade de Tratamento Oncologico Ltda, Lages · Liga Norte Riograndense Contra o Cancer, Natal · Centro Gaucho Integrado, Porto Alegre · Hospital de Clinicas de Porto Alegre, Porto Alegre · Instituto Americas, Rio de Janeiro · Instituto Nacional de Cancer Jose Alencar Gomes da Silva, Rio de Janeiro · Ensino e Terapia de Inovação Clínica AMO - ETICA, Salvador · Casa de Saude Santa Marcelina, São Paulo · Hospital Alemão Oswaldo Cruz, São Paulo · Clinical Hospital of Medicine School at Sao Paulo University, São Paulo · AC Camargo Cancer Center, São Paulo · Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo

  Registry updated 2026-11-04

• NCT05139017

  A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

  Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC

  Hospital Erasto Gaertner ( Site 2302), Curitiba · Liga Norte Riograndense Contra o Câncer ( Site 2305), Natal · Hospital Paulistano ( Site 2300), São Paulo

  Registry updated 2026-11-03

• NCT05952024

  Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

  Trial Treatment · Phase 2 · AstraZeneca

  Barretos · Belo Horizonte · Brasília · Campinas · Curitiba · Florianópolis · Goiânia · Natal · Porto Alegre · Recife · Ribeirão Preto · Rio de Janeiro · São José do Rio Preto · São Luís · São Paulo · Sorocaba

  Registry updated 2026-10-30

• NCT06395103

  Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

  Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC

  Fundação Pio XII - Hospital de Câncer de Barretos ( Site 1264), Barretos · Hospital Erasto Gaertner-CEPEP - Pesquisa Clínica ( Site 1268), Curitiba · Hospital de Clinicas de Porto Alegre ( Site 1265), Porto Alegre · Fundação Faculdade Regional de Medicina de São José do Rio Preto-Centro Integrado de Pesquisa ( Site 1267), São José do Rio Preto

  Registry updated 2026-10-30

• NCT06717347

  A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  CEONC ( Site 0412), Cascavel · Hospital Erasto Gaertner ( Site 0401), Curitiba · CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 0403), Florianópolis · Liga Norte Riograndense Contra o Cancer ( Site 0407), Natal · Hope ( Site 0413), Ribeirão Preto · Clinica Advanze ( Site 0411), São Carlos · Hospital Paulistano ( Site 0406), São Paulo · Hospital das Clinicas FMUSP ( Site 0402), São Paulo · F. F. R. M. São Jose do Rio Preto ( Site 0404), SJRP

  Registry updated 2026-10-21

• NCT07882576

  A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell Lymphoma

  Research · AstraZeneca

  UNICAMP, Campinas · Hospital Erasto Gaertner, Curitiba · Hospital Municipal da Vila Santa Catarina, São Paulo · AC Camargo Cancer Center, São Paulo · Hospital Israelita Albert Einstein, São Paulo

  Registry updated 2026-10-20

• NCT05006716

  A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

  Trial Treatment · Phase 1/2 · BeOne Medicines

  Hospital Sirio Libanes Brasilia, Brasília · Hospital Erasto Gaertner, Curitiba · Centro Gaucho Integrado de Oncologia Hospital Mae de Deus, Porto Alegre · Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo · Instituto Dor de Pesquisa E Ensino Sao Paulo, São Paulo · Hospital Nove de Julho - dasa, São Paulo · Real E Benemerita Associacao Portuguesa de Sao Paulo, São Paulo

  Registry updated 2026-10-05

• NCT05541341

  Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies

  Research · Novartis Pharmaceuticals

  Curitiba · Minas Gerais · Salvador · São Paulo

  Registry updated 2025-06-06

All Diffuse large B-cell lymphoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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