Duchenne muscular dystrophy: open trials in United Kingdom

17 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07587242
A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 Skipping
Trial Treatment · Phase 3 · Avidity Biosciences, Inc.
Royal Victoria Infirmary, Newcastle · University of Oxford and Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-10-13
NCT07856329
A Clinical Study to Assess Safety, Efficacy and Pharmacodynamic Profile of GNT0004 in Duchenne Muscular Dystrophy
Trial Treatment · Phase 2/3 · Genethon
Great Ormond Street Hospital for Children, London · The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
Registry updated 2026-10-13
NCT06066580
Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy
Trial Treatment · Phase 2 · Edgewise Therapeutics, Inc.
University College London Hospital, London · St. George's University Hospitals NHS Foundation Trust, London · Newcastle Freeman Hospital, Newcastle · Salford Royal Hospital, Salford
Registry updated 2026-09-17
NCT07037862
A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to Evaluate the Safety and Efficacy of ENTR-601-44
Trial Treatment · Phase 1/2 · Entrada Therapeutics, Inc.
Leeds General Infirmary, Leeds · Alder Hey Children's NHS Foundation Trust, Liverpool · Great Ormond Street Hospital for Children, London · Royal Manchester Children's Hospital, Manchester · Freeman Hospital, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-08-13
NCT07038824
A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping to Evaluate the Safety and Efficacy of ENTR-601-45
Trial Treatment · Phase 1/2 · Entrada Therapeutics, Inc.
Leeds General Infirmary, Leeds · Alder Hey Children's NHS Foundation Trust, Liverpool · Great Ormond Street Hospital for Children, London · Royal Manchester Children's Hospital, Manchester · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-08-13
NCT05933057
Efficacy, Safety and Tolerability of Givinostat in Non-ambulant Patients With Duchenne Muscular Dystrophy
Trial Treatment · Phase 3 · Italfarmaco
NHS Greater Glasgow and Clyde, Royal Hospital for Children, Glasgow · Newcastle upon Tyne Hospitals NHS Foundation Trust - Newcastle University, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-07-24
NCT07573631
An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of BMN 351 in Participants With Duchenne Muscular Dystrophy
Trial Treatment · Phase 2 · BioMarin Pharmaceutical
Great Ormond Street Hospital NHS Foundation Trust, London
Registry updated 2026-07-24
NCT06138639
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Trial Treatment · Phase 1/2 · Solid Biosciences Inc.
Great Ormond Street Hospital, London
Registry updated 2026-07-08
NCT07682129
Long-Term Extension Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon Skipping to Evaluate the Safety and Efficacy of Endosomal Escape Vehicle Phosphorodiamidate Morpholino Oligomer Platform Products (ELEVATE-LTE)
Trial Treatment · Phase 2 · Entrada Therapeutics, Inc.
Leeds General Infirmary, Leeds · Alder Hey Children's NHS Foundation Trust, Liverpool · Great Ormond Street Hospital for Children, London · Royal Manchester Children's Hospital, Manchester · Freeman Hospital, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-07-02
NCT07423026
A Remote Study Using Technology to Assess Outcomes in DMD
Research · University of Oxford
Oxford University, Oxford
Registry updated 2026-06-10
NCT07209332
Open-Label Extension Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy
Trial Treatment · Phase 2 · Wave Life Sciences USA, Inc.
Oxford Children's Hospital, Oxford University Hospitals NHS Foundation Trust, Headington
Registry updated 2026-03-06
NCT03882827
Natural History of Duchenne Muscular Dystrophy
Research · Genethon
Great Ormond Street Hospital & University College London Hospital, London · Institute of Genetic Medicine, Newcastle
Registry updated 2026-02-12
NCT05967351
A Long-term Follow-up Study of Participants Who Received Delandistrogene Moxeparvovec (SRP-9001) in a Previous Clinical Study
Trial Treatment · Phase 3 · Sarepta Therapeutics, Inc.
Great Ormond Street Hospital For Children NHS Foundation Trust, London · Institute of Translational and Clinical Research, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-02-06
NCT03373968
Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study
Trial Treatment · Phase 2/3 · Italfarmaco
The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Gobowen · Alder Hey Children's Hospital NHS Trust, Liverpool · UCL Great Ormond Street Institute of Child Health, Dubowitz Neuromuscular Centre and MRC Centre for NMD, London · The John Walton Muscular Dystrophy Research Centre, Newcastle upon Tyne
Registry updated 2026-01-21
NCT06643442
Repurposing Empagliflozin for DMD-associated Cardiomyopathy in Children 6-18 Years of Age
Trial Treatment · Phase 2 · Sebastiano Lava
Great Ormond Street Hospital NHS Foundation Trust, London
Registry updated 2025-08-15
NCT06769633
Pharmacokinetics and Safety of Givinostat in DMD Patients Ages From at Least 2 Years to Less Then 6 Years Old
Trial Treatment · Phase 2 · Italfarmaco
Leeds Teaching Hospital NHS Trust, Leeds · Great Ormond Street Hospital (GOSH), London · Newcastle upon Tyne Hospitals NHS Foundation Trust - Newcastle University, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2025-07-10
NCT06711692
The U.K. NorthStar Clinical Network
Research · University College, London
Aberdeen, NHS Grampian, Aberdeen · Belfast Health and Social Care Trust, Belfast · Birmingham Heartlands Hospital, Birmingham · Birmingham Children's Hospital, Birmingham · Birmingham Community Healthcare NHS Foundation Trust, Birmingham · University Hospitals Bristol and Weston, Bristol · Cambridge University Hospitals, Cambridge · Cardiff and Vale University Health Board, Cardiff · NHS Dundee - Tayside, Dundee · NHS Greater Glasgow and Clyde, Glasgow · Lancashire Teaching Hospitals NHS Foundation Trust, Lancaster · Leeds Teaching Hospitals NHS Trust, Leeds · University Hospitals of Leicester NHS Trust, Leicester · Alder Hey Children's Hospital Trust, Liverpool · Evelina London Children's Hospital, London · Great Ormond Street Hospital For Children NHS Foundation Trust, London · Manchester University NHS Foundation Trust, Manchester · Newcastle Hospitals NHS Foundation Trust, Newcastle · Nottingham University Hospitals NHS Trust, Nottingham · The Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry · Oxford University Hospitals, Oxford · University Hospitals Plymouth NHS Trust, Plymouth · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield · University Hospital Southampton NHS Foundation Trust, Southampton · Swansea Bay University Health Board, Swansea
Registry updated 2024-12-02

All Duchenne muscular dystrophy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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