Endometrial cancer: open trials in Canada

34 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 2 · Bayer
Queen Elizabeth II Health Sciences Centre | Oncology, Halifax · Research Institute of the McGill University Health Centre | Women Health's Research Unit, Montreal · Princess Margaret Cancer Centre | Medical Oncology and Hematology, Toronto
Registry updated 2026-11-04
NCT07166094
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Trial Treatment · Phase 3 · Genmab
Arthur J E Child Cancer Comp, Calgary · MUHC, GLEN site, Montreal · BC Cancer - Vancouver, Vancouver
Registry updated 2026-11-03
NCT07286331
A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)
Trial Treatment · Phase 3 · GlaxoSmithKline
Montreal · Toronto
Registry updated 2026-11-03
NCT07684599
A Study to Investigate Mocertatug Rezetecan as Maintenance Treatment for Participants With MMRp Endometrial Cancer (BEHOLD-Endometrial02)
Trial Treatment · Phase 3 · GlaxoSmithKline
Montreal · Toronto
Registry updated 2026-11-03
NCT07516210
Adaptive Radiotherapy for Safe Hypofractionation
Trial Treatment · Phase 2 · Centre hospitalier de l'Université de Montréal (CHUM)
Centre Hospitalier de l'Université de Montréal, Montreal
Registry updated 2026-10-29
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Cross Cancer Institute, Edmonton · Sunnybrook Research Institute, Toronto · Princess Margaret Cancer Centre, Toronto · BC Cancer - Vancouver, Vancouver
Registry updated 2026-10-26
NCT06340568
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Trial Treatment · Phase 3 · BioNTech SE
Jewish General Hospital, Montreal · Health Sciences Centre, St. John's · Princess Margaret Cancer C, Toronto
Registry updated 2026-10-16
NCT05640999
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Trial Treatment · Phase 2 · Canadian Cancer Trials Group
Royal Victoria Regional Health Centre, Barrie · Arthur J.E. Child Comprehensive Cancer Centre, Calgary · Cross Cancer Institute, Edmonton · Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton · BCCA - Kelowna, Kelowna · London Health Sciences Centre Research Inc., London · Trillium Health Partners - Credit Valley Hospital, Mississauga · CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal · The Jewish General Hospital, Montreal · BCCA - Prince George, Prince George · CIUSSS de l'Estrie - Centre hospitalier, Sherbrooke · University Health Network, Toronto · Odette Cancer Centre, Toronto · BCCA - Vancouver, Vancouver · BCCA - Victoria, Victoria
Registry updated 2026-10-14
NCT05123482
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
Trial Treatment · Phase 1/2 · AstraZeneca
Calgary · Montreal · Ottawa · Toronto · Vancouver
Registry updated 2026-10-13
NCT06952504
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Royal Victoria Regional Health Centre (Site 0615), Barrie · London Health Sciences Centre (Site 0611), London · CIUSSS de l'Est-de-l'Île-de-Montréal (Site 0607), Montreal · McGill University Health Centre (Site 0604), Montreal · Centre Hospitalier de l Universite de Montreal - CHUM (Site 0605), Montreal · Jewish General Hospital (Site 0606), Montreal · Sault Area Hospital (Site 0616), Sault Ste. Marie · CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke (Site 0608), Sherbrooke · NL Health Services (Site 0602), St. John's · BC Cancer Surrey (Site 0621), Surrey · Sunnybrook Research Institute (Site 0610), Toronto · Princess Margaret Cancer Center (Site 0609), Toronto · Windsor Regional Cancer Program (Site 0614), Windsor · CancerCare Manitoba (Site 0617), Winnipeg
Registry updated 2026-10-13
NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Trial Treatment · Phase 3 · AstraZeneca
Calgary · Edmonton · Halifax · London · Montreal · Québec · Toronto · Winnipeg
Registry updated 2026-10-13
NCT07871838
Safety, Efficacy and Quality of Life After Adjuvant Hypofractionated Radiotherapy for Endometrial Cancer
Trial Treatment · McGill University Health Centre/Research Institute of the McGill University Health Centre
McGill University Health Centre-Cedars Cancer Centre, Montreal
Registry updated 2026-10-13
NCT05255653
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features
Trial Treatment · Phase 3 · Leiden University Medical Center
Juravinski Cancer Center, Hamilton · BCCA - Kelowna, Kelowna · Kingston Health Sciences Centre, Kingston · London Regional Cancer Centre, London · Centre Hospitalier de Universite de Montreal, Montreal · Maisonneuve-Rosemont Hospital, Montreal · Jewish General Hospital, Montreal · Allan Blair Cancer Centre, Regina · Saint John Regional Center, Saint John · Saskatoon Cancer Centre, Saskatoon · Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke · Sunnybrook Health Science Centre, Toronto · Princess Margaret Cancer Centre, Toronto · BC Cancer - Vancouver, Vancouver · BCCA - Victoria, Victoria
Registry updated 2026-10-08
NCT05797168
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
Trial Treatment · Phase 1/2 · AstraZeneca
Edmonton · London · Montreal · Toronto
Registry updated 2026-10-05
NCT06073184
Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometrium
Trial Treatment · Phase 2 · GynOncTrials
Princess Margaret Cancer Centre - University Health Network, Toronto
Registry updated 2026-10-05
NCT07840443
Phase II Study of CAmizestrant in Resectable Endometrial Adenocarcinoma
Trial Treatment · Phase 2 · University Health Network, Toronto
Kingston Health Sciences Centre, Kingston · Hôpital Maisonneuve-Rosemont, Montreal · Jewish General Hospital, Montreal · The Ottawa Hospital, Ottawa · Princess Margaret Cancer Centre - University Health Network, Toronto · BC Cancer - Vancouver, Vancouver
Registry updated 2026-09-25
NCT05489211
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Trial Treatment · Phase 2 · AstraZeneca
Montreal · Québec · Toronto
Registry updated 2026-09-23
NCT06038032
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
Trial Treatment · University of Alberta
University of Alberta, Edmonton · University of Toronto, Toronto
Registry updated 2026-09-21
NCT07213609
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
Trial Treatment · Phase 1/2 · GlaxoSmithKline
Hamilton · Montreal · Toronto
Registry updated 2026-09-16
NCT07194551
Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire
Trial Treatment · University of British Columbia
VGH Research Pavilion, Vancouver
Registry updated 2026-09-03
NCT05592626
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Marengo Therapeutics, Inc.
Princess Margaret Cancer Centre, Toronto
Registry updated 2026-08-11
NCT07044336
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
Trial Treatment · Phase 3 · AstraZeneca
Edmonton · Hamilton · Kingston · Montreal · Winnipeg
Registry updated 2026-07-29
NCT05208762
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Trial Treatment · Phase 1 · Seagen, a wholly owned subsidiary of Pfizer
McGill University Health Centre, Montreal · University Health Network, Toronto · University Health Network, Princess Margaret Hospital, Toronto
Registry updated 2026-07-22
NCT06730347
A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Trial Treatment · Phase 2 · MacroGenics
McGill University, Montreal · Princess Margaret Cancer Center, Toronto
Registry updated 2026-06-02
NCT07581288
Measurement of Urinary Hormones in Patients With Abnormal Uterine Bleeding to Study Uterine Cancer Progression
Research · University of British Columbia
Vancouver General Hospital Research Pavillion, Vancouver
Registry updated 2026-05-12

All Endometrial cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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