Epilepsy: open trials in Australia

18 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT05667142
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Austin Health Pharmacy Clinical Trials, Heidelberg · Southern Neurology, Kogarah · The Alfred Hospital, Melbourne · St Vincent's Hospital Melbourne, Clinical Neurosciences, Melbourne · The Royal Melbourne Hospital, Parkville · Mater Misericordiae Ltd, South Brisbane
Registry updated 2026-11-02
NCT05716100
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Royal Prince Alfred Hospital, Camperdown · Alfred Hospital, Melbourne · Royal Melbourne Hospital, Melbourne · Austin Health, Melbourne · Prince of Wales Hospital, Randwick · Westmead Hospital, Westmead
Registry updated 2026-11-02
NCT05718817
An Open-label Study of XEN1101 in Epilepsy
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Royal Prince Alfred Hospital, Camperdown · St Vincent's Hospital Melbourne, Fitzroy · Austin Health Pharmacy Clinical Trials, Heidelberg · Southern Neurology, Kogarah · Alfred Hospital Neurology CT Dept of Neuroscience, Melbourne · The Royal Melbourne Hospital, Parkville · Prince of Wales Hospital, Randwick · Mater Misericordiae Ltd, South Brisbane, South Brisbane · Westmead Hospital Dept. of Neurology Epilepsy Unit, Westmead
Registry updated 2026-11-02
NCT05419492
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Trial Treatment · Phase 1/2 · Encoded Therapeutics
The Royal Children's Hospital, Melbourne
Registry updated 2026-10-23
NCT07881185
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Research · Istituto Giannina Gaslini
The Florey Institute of Neuroscience and Mental Health, Melbourne
Registry updated 2026-10-19
NCT06908226
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Trial Treatment · Phase 3 · Longboard Pharmaceuticals
Royal Brisbane and Women's Hospital (RBWH), Brisbane · Queensland Children's Hospital (Lady Cilento Children's Hospital), Brisbane · Austin Hospital, Heidelberg · The Royal Children's Hospital (RCH) Melbourne, Parkville · Sydney Children's Hospital - Randwick, Randwick · The Children's Hospital-Westmead - Heart Centre for Children, Westmead
Registry updated 2026-10-14
NCT06798896
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
Trial Treatment · Phase 2 · Supernus Pharmaceuticals, Inc.
Royal Adelaide Hospital, Adelaide · Monash Medical Centre, Clayton · St Vincent's Hospital Melbourne, Fitzroy · Royal Brisbane and Women's Hospital, Herston · The Alfred Hospital, Melbourne · The Perron Institute for Neurological and Translational Science, Nedlands · Royal Melbourne Hospital, Parkville
Registry updated 2026-10-01
NCT06612775
A Study to Evaluate the Safety, Tolerability, and Efficacy of CB03-154 in Adult Patients With Focal Epilepsy
Trial Treatment · Phase 2 · Shanghai Zhimeng Biopharma, Inc.
Alfred Health, Melbourne
Registry updated 2026-09-22
NCT07640191
Feasibility Study of the iVEAcare Neuromodulation System for the Treatment of Drug-Resistant Epilepsy
Trial Treatment · iVEAcare
Monash Health, Clayton · St. Vincent's Hospital, Fitzroy · Austin Hospital, Heidelberg · Royal Brisbane & Women s Hospital, Herston · The Alfred Hospital, Melbourne · Melbourne Health, Parkville · The Mater, South Brisbane
Registry updated 2026-09-22
NCT07775872
Prospective Natural History Study of POLG Disease
Research · The POLG Foundation
Prince of Wales Hospital, Sydney, Sydney
Registry updated 2026-09-15
NCT05947656
Evaluation of the NaviFUS System in Drug Resistant Epilepsy
Trial Treatment · Genovate-NaviFUS (Australia) Pty Ltd.
The Alfred, Melbourne
Registry updated 2026-09-10
NCT07156201
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ABS-1230 Given Orally Compared With Placebo in Healthy Participants Aged 18 to 55 Years
Trial Treatment · Phase 1 · Actio Biosciences, Inc.
Scientia Clinical Research, Sydney
Registry updated 2026-08-07
NCT06138808
5-SENSE Score Validation Study
Research · Duke University
Mater Health, Brisbane · Monash University, Melbourne · Alfred Health, Melbourne
Registry updated 2026-06-05
NCT05518578
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
Trial Treatment · Phase 2 · Supernus Pharmaceuticals, Inc.
Box Hill Hospital, Box Hill · Royal Brisbane and Women's Hospital, Brisbane · The Austin Hospital, Heidelberg · The Alfred Hospital, Melbourne · The Royal Melbourne Hospital, Parkville · Prince of Wales Hospital, Randwick · Royal Prince Alfred Hospital, Sydney · Westmead Hospital, Sydney
Registry updated 2026-04-21
NCT07238868
An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With Epilepsy
Trial Treatment · Phase 2 · Shanghai Zhimeng Biopharma, Inc.
Alfred Health, Melbourne
Registry updated 2025-11-20
NCT06401538
BMB-101 in Absence Epilepsy and DEE
Trial Treatment · Phase 2 · Bright Minds Biosciences Pty Ltd
St Vincent's Hospital Melbourne, Fitzroy · Austin Health, Heidelberg · Royal Brisbane and Womans Hospital, Herston · Alfred Health, Melbourne · The Prince of Wales Hospital, Randwick
Registry updated 2025-08-12
NCT05219617
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
Trial Treatment · Phase 3 · SK Life Science, Inc.
Austin Hosptial, Heidelberg · Alfred Health, Melbourne · Perth's Children Hospital, Nedlands · Queensland Children's Hospital, South Brisbane
Registry updated 2025-07-24
NCT06908356
An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
Trial Treatment · Phase 2 · Praxis Precision Medicines
Praxis Research Site, Heidelberg · Praxis Research Site, Melbourne
Registry updated 2025-04-03

All Epilepsy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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