Epilepsy: open trials in Germany

18 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT05667142
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Universitaetsklinikum Aachen AöR, Aachen · Gesellschaft Fuer Epilepsieforschung, Bielefeld · Goethe University Frankfurt, Frankfurt Am Main · Medical Center- University of Freiburg, Freiburg im Breisgau · Philipps-Universitaet Marburg, Marburg · Klinikum der Universitaet Muenchen AöR, Munich · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-11-02
NCT05716100
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Universitaetsklinikum Aachen AöR, Aachen · Gesellschaft Fuer Epilepsieforschung, Bielefeld · Goethe University Frankfurt, Frankfurt Am Main
Registry updated 2026-11-02
NCT05718817
An Open-label Study of XEN1101 in Epilepsy
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Universitaetsklinikum Aachen AöR, Aachen · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Gesellschaft Fuer Epilepsieforschung, Bielefeld · Rheinische Friedrich-Wilhelms-Universitaet Bonn, Bonn · Universitätsklinikum Frankfurt, Frankfurt · Medical Center- University of Freiburg, Freiburg im Breisgau · Philipps-Universitaet Marburg, Marburg · Klinikum der Universitaet Muenchen AöR, Munich · Epilepsiezentrum Kleinwachau gGmbH, Radeberg · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-11-02
2025-521640-38-00
Open Label Extension Clinical Trial of Vormatrigine in Adult Patients with Epilepsy.
Trial Treatment · Phase 3 · Praxis Precision Medicines Inc.
Gesellschaft Fuer Epilepsieforschung, Bielefeld · Universitaetsklinikum Bonn AöR, Bonn · Universitaetsklinikum Frankfurt AöR, Frankfurt Am Main · Universitaetsklinikum Giessen und Marburg GmbH, Marburg · Klinikum Osnabrueck GmbH, Osnabrueck · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-10-29
NCT07881185
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Research · Istituto Giannina Gaslini
University Hospital Bonn, Bonn
Registry updated 2026-10-19
NCT06908226
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Trial Treatment · Phase 3 · Longboard Pharmaceuticals
Gesellschaft fuer Epilepsieforschung e.V., Bielefeld · Universitätsklinikum Bonn, Bonn · Universitätsklinikum Frankfurt - Klinikum der Goethe-Universität, Frankfurt am Main · Universitaetsklinikum Schleswig-Holstein (UKSH) - Campus Kiel - Klinik fuer Psychosomatik und Psy..., Kiel
Registry updated 2026-10-14
2024-514499-42-00
Efficacy and Safety Study of Once-Daily Extended-Release Levetiracetam in Drug-resistant Focal Onset Seizures
Trial Treatment · Phase 3 · Neuraxpharm Pharmaceuticals S.L.
Gesellschaft Fuer Epilepsieforschung, Bielefeld · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-13
NCT07019922
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
Trial Treatment · Phase 3 · Praxis Precision Medicines
Praxis Research Site, Bonn
Registry updated 2026-08-03
NCT07287163
Clinical Trial of Vormatrigine in Adult Patients With Epilepsy
Trial Treatment · Phase 3 · Praxis Precision Medicines
Praxis Research Site, Bielefeld · Praxis Research Site, Tübingen
Registry updated 2026-08-03
NCT04715646
A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
Trial Treatment · Phase 3 · UCB Biopharma SRL
Ep0156 209, Freiburg im Breisgau
Registry updated 2026-07-27
NCT06138808
5-SENSE Score Validation Study
Research · Duke University
Epilepsy Centre, University Hospital Freiburg, Freiburg im Breisgau
Registry updated 2026-06-05
NCT06443463
Long-term Safety and Tolerability of BHV-7000
Trial Treatment · Phase 2 · Biohaven Therapeutics Ltd.
Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Gesellschaft Fuer Epilepsieforschung, Bielefeld · Universitaetsklinikum Bonn AöR, Bonn · Universitaetsklinikum Erlangen AöR, Erlangen · Goethe University Frankfurt, Frankfurt Am Main · Medical Center- University of Freiburg, Freiburg im Breisgau · Diakonie Kork, Kehl · Universitaetsklinikum Leipzig Aor, Leipzig · Philipps-Universitaet Marburg, Marburg · Klinikum der Universitaet Muenchen AöR, Munich · Klinikum Osnabrueck GmbH, Osnabrueck · Epilepsiezentrum Kleinwachau gGmbH, Radeberg · ZfP Südwürttemberg, Ravensburg · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-05-01
NCT06922175
REACH: RWE Retrospective Study to Evaluate Cenobamate Impact on Health Care Resource Utilization
Research · Aziende Chimiche Riunite Angelini Francesco S.p.A
Epilepsiezentrums am Neurozentrum des Universitätsklinikum Freiburg, Freiburg im Breisgau · Epileptologicum, Hamburg · Diakonie Kork, Epilepsiezentrum, Kork
Registry updated 2025-10-02
NCT05219617
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
Trial Treatment · Phase 3 · SK Life Science, Inc.
Universitatsklinikum Erangen, Erlangen · Kleinwachau Sächsisches Epilepsiezentrum, Radeberg
Registry updated 2025-07-24
NCT07009990
Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
Research · University Medicine Greifswald
University Medicine Greifswald, Greifswald
Registry updated 2025-06-08
NCT06958341
Neuroimmunology Registry and Biobank
Research · Charite University, Berlin, Germany
Charité Universitätsmedizin Berlin, Berlin · Universität Ulm, Ulm
Registry updated 2025-05-06
NCT06836687
Effect of the New Definition of Epilepsies of the ILAE of 2014 on the Diagnosis After the First Seizure
Research · University Hospital Marburg
c/o Klinik für Neurologie, Marburg
Registry updated 2025-02-20
NCT06383689
Placebo Optimization of the Presurgical Long-term Video-EEG Monitoring
Trial Treatment · University Hospital, Bonn
Department of Epileptology, University Hospital Bonn, Bonn
Registry updated 2024-06-10

All Epilepsy trials and the map

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