Glioblastoma: open trials in Italy

20 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT06914128
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Trial Treatment · Phase 1/2 · Bayer
Centro di Riferimento Oncologico di Aviano - Oncologia Medica e dei Tumori Immuno-Correlati, Aviano · Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1, Milan · I.F.O. Istituti Fisioterapici Ospitalieri - Sperimentazioni cliniche Fase 1 e Medicina di precisione, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Fase I, Rome · Humanitas Mirasole S.p.A. - Oncologia Medica ed Ematologia, Rozzano
Registry updated 2026-10-28
NCT06551909
Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)
Trial Treatment · IRCCS San Raffaele
IRCCS San Raffaele Scientific Institute, Milan
Registry updated 2026-10-27
NCT06385132
Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck Cancer
Research · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma
Registry updated 2026-10-14
NCT04094610
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.
Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan
Registry updated 2026-09-25
NCT07832734
Metabolomics and Transcriptomics of Low- and High-Grade Gliomas
Research · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
IRCCS Galeazzi-Sant'Ambrogio, Milan
Registry updated 2026-09-22
NCT05904119
Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study
Trial Treatment · Phase 3 · European Organisation for Research and Treatment of Cancer - EORTC
Instituto Di Ricovero E Cura A Carattere Scientifico, Bologna · Azienda Ospedaliero-Universitaria Careggi, Florence · Ospedale Mater Salutis Di Legnago, Legnago · Istituto Oncologico Veneto, Padova · Ospedale Isola Tiberina - Gemelli Isola, Rome · Universita' Degli Studi Di Roma La Sapienza, Rome · Humanitas Research Hospital, Rozzano
Registry updated 2026-06-08
NCT07567196
PET-Guided Resection in High-Grade Gliomas
Research · Universita degli Studi di Genova
IRCCS Azienda Ospedaliera Metropolitana, Genova · AOU Città della Salute e della Scienza, Torino
Registry updated 2026-05-05
NCT04945148
Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Trial Treatment · Phase 2 · Hopital Foch
Spidali Riuniti Di Livorno, Livorno · Istituto Nazionale Carlo Besta, Milan
Registry updated 2025-11-21
2024-520228-28-00
Clinical trial on the use of metformin in addition to standard therapy in patients with high-grade glioma
Trial Treatment · Phase 2 · Universita Degli Studi Di Milano Bicocca
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan
Registry updated 2025-11-03
NCT05929495
Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma
Trial Treatment · Phase 2 · University of Milano Bicocca
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan
Registry updated 2025-07-25
NCT03175224
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Trial Treatment · Phase 2 · Apollomics Inc.
Azienda Ospedaliero-Universitaria delle Marche, Ancona · Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l, Meldola · San Raffaele Hospital, Milan · Istituto Europeo di Oncologia s.r.l, Milan · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan · Istituto Oncologico Veneto, Padova · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2025-06-27
NCT05775458
Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
Research · IRCCS San Raffaele
IRCCS San Raffaele Scientific Institute, Milan
Registry updated 2025-06-11
NCT05941234
Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome
Registry updated 2025-03-13
NCT06781372
Patient's Derived Organoids for Drug Screening in Glioblastoma
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2025-03-13
NCT06113705
Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study.
Trial Treatment · Istituto Clinico Humanitas
IRCCS Istituto Clinico Humanitas, Rozzano
Registry updated 2025-01-31
NCT06258018
Niraparib and Temozolomide in Patients Glioblastoma
Trial Treatment · Phase 1/2 · Armando Santoro, MD
Istituto Clinico Humanitas, Rozzano
Registry updated 2024-08-30
2024-516211-25-00
A long-term monitoring study of patients suffering from a malignant neoplasm of the central nervous system previously treated with hematopoietic stem cells
Trial Treatment · Phase 1/2 · Genenta Science S.p.A.
IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Ospedale San Raffaele S.r.l., Milan
Registry updated 2024-08-26
NCT04523688
Vaccination with Autologous Dendritic cells loaded with Autologous Tumour homogenate in Glioblastoma: a phase II Study
Trial Treatment · Phase 2 · Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l, Meldola
Registry updated 2024-07-15
NCT06297512
Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).
Trial Treatment · Phase 2 · Iacopo Sardi
Meyer Children's Hospital IRCCS, Florence
Registry updated 2024-03-07
NCT04443010
Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma
Trial Treatment · Phase 1/2 · Philogen S.p.A.
Ospedale Isola Tiberina - Gemelli Isola, Rome
Registry updated 2023-10-10

All Glioblastoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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