Haemophilia: open trials in United Kingdom

18 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT06706206
The CACHE Study: Coronary Artery Care in HaEmophilia
Research · Oxford University Hospitals NHS Trust
Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-11-06
NCT07416604
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Trial Treatment · Phase 3 · Hoffmann-La Roche
University Hospital of Wales, Cardiff · St Thomas Hospital, London · Royal Free Hospital - PPDS, London · Great Ormond Street Hospital, London · The Royal London Hospital, London
Registry updated 2026-11-03
NCT07830732
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
Trial Treatment · Phase 3 · Novo Nordisk A/S
Queen Elizabeth Hospital, Birmingham - Haemophilia, Birmingham · University Hospital of Wales - Haemophilia, Cardiff · Royal Free Hospital - Haemophilia, London · St Thomas' Hospital - Haemostasis and Thrombosis Centre, London · Nuffield Orthopaedic Centre - Oxford Haemophilia and Thrombosis Centre, Oxford · Royal Hallamshire Hospital, Sheffield
Registry updated 2026-10-28
NCT05145127
Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
Trial Treatment · Phase 3 · Pfizer
Birmingham Children's Hospital, Birmingham · Guy's & St Thomas' NHS Foundation Trust, St Thomas' Hospital, London · Guy's & St Thomas' NHS Foundation Trust, London · Royal Victoria Infirmary, Newcastle upon Tyne
Registry updated 2026-10-26
NCT07416526
A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A
Trial Treatment · Phase 3 · Hoffmann-La Roche
University Hospital of Wales, Cardiff · St Thomas Hospital, London · The Royal London Hospital, London · Churchill Hospital, Oxford
Registry updated 2026-10-26
NCT06379789
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Trial Treatment · Phase 1/2 · Regeneron Pharmaceuticals
Queen Elizabeth Hospital Birmingham, Birmingham · Addenbrooke's Hospital, Cambridge University Hospitals NHS FT, Cambridge · Glasgow Royal Infirmary - Clinical Research Facility, Glasgow · Hammersmith Hospital Comprehensive Care Centre, London · St Thomas Hospital, London · Royal Free London NHS Foundation Trust, London · Pathology and Pharmacy Building, The Royal London Hospital, London · Oxford Haemophilia and Thrombosis Centre (OHTC), Oxford
Registry updated 2026-10-21
NCT07080905
Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B
Trial Treatment · Phase 3 · CSL Behring
St Thomas Hospital, London · John Radcliffe Hospital - Oxford University Hospitals NHS, Oxford
Registry updated 2026-10-20
NCT05611801
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Trial Treatment · Phase 3 · Pfizer
Birmingham Children's Hospital, Birmingham · Evelina London Children's Hospital, London · Royal Manchester Children's Hospital, Manchester · Royal Victoria Infirmary, Newcastle upon Tyne · Freeman Hospital, Newcastle upon Tyne
Registry updated 2026-10-14
NCT03690336
Adverse Event Data Collection From External Registries on Nonacog Beta Pegol
Research · Novo Nordisk A/S
European Haemophilia Safety Surveillance Registry, Sheffield
Registry updated 2026-10-08
NCT07220564
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Trial Treatment · Phase 1 · Novo Nordisk A/S
Queen Elizabeth Hospital, Birmingham - Haemophilia, Birmingham · Royal Free Hospital - Haemophilia, London · Royal Hallamshire Hospital, Sheffield
Registry updated 2026-09-18
NCT03745924
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYN
Research · Novo Nordisk A/S
Aberdeen Royal Infirmary - Haematology, Aberdeen · University Hospital of Wales - Haemophilia, Cardiff · Royal Manchester Children's Hospital, Manchester · Royal Hallamshire Hospital, Sheffield
Registry updated 2026-06-12
NCT03695978
Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients
Research · Octapharma
Birmingham Children's Hospital NHS Foundation Trust, Birmingham · John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Headington · Great Ormond Street Hospital for Children NHS Trust, Haemophilia Centre, London · Newcastle Haemophilia Comprehensive Care Centre, Royal Victoria Infirmary, Newcastle upon Tyne
Registry updated 2026-06-02
NCT05935358
Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study
Trial Treatment · Phase 4 · Octapharma
St James's University Hospital, Leeds
Registry updated 2026-05-12
NCT05936580
Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery
Trial Treatment · Phase 4 · Octapharma
St James's University Hospital, Leeds
Registry updated 2026-05-12
NCT05768386
A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)
Research · Phase 4 · BioMarin Pharmaceutical
Addenbrooke's Hospital, Hemophilia and Thrombophilia Center, Cambridge · Glasgow Royal Infirmary, Department of Hematology, Glasgow · Hammersmith Hospital, Clinical Research Facility, Centre for Translational and Experimental Medicine, London · Queen Elizabeth Hospital Birmingham. Adult Hemophilia Centre, West Midlands Adult Comprehensive Care Hemophilia Centre, London · Royal London Hospital, Barts and the London Hemophilia Center, London · St Thomas' Hospital, Centre for Hemophilia, Hemostasis and Thrombosis, London · Nuffield Orthopaedic Centre, Hemophilia & Thrombosis Center, Oxford · University Hospital Southampton NHS Foundation Trust, Southampton
Registry updated 2026-01-12
NCT02979119
The European Paediatric Network for Haemophilia Management ( PedNet Registry)
Research · PedNet Haemophilia Research Foundation
Birmingham Children's Hospital NHS Trust - Department of Haematology, Birmingham · Royal Hospital for Sick Children, Edinburgh · Department of Haematology Royal Hospital for Sick Children, Glasgow · Haemophila Center Great Ormond Street Hospital for Children, London
Registry updated 2025-09-16
NCT05962398
Long-term Follow-up Study of Male Adults With Hemophilia B Previously Treated With Etranacogene Dezaparvovec (CSL222)
Research · Phase 2/3 · CSL Behring
18-54 Addenbrooke's Hospital, Cambridge · 18-52 Barts Health NHS Trust, London · 18-53 University Hospital Southampton NHS Foundation Trust, Southampton
Registry updated 2025-07-18
NCT04817462
Liver Biopsy In Haemophilia Gene Therapy
Trial Treatment · University College, London
Royal Free Hospital, London
Registry updated 2024-12-20

All Haemophilia trials and the map

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