Haemophilia: open trials in South Africa

7 open trials have a site in South Africa. Registry data; only the trial team decides who can take part.

NCT07416604
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Trial Treatment · Phase 3 · Hoffmann-La Roche
Haemophilia Comprehensive Care Centre, Parktown
Registry updated 2026-11-03
NCT07830732
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
Trial Treatment · Phase 3 · Novo Nordisk A/S
Charlotte Maxeke Johannesburg Academic Hospital, Parktown, Johannesburg
Registry updated 2026-10-28
NCT05145127
Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
Trial Treatment · Phase 3 · Pfizer
Worthwhile Clinical Trials, Benoni · Wits Health Consortium, Johannesburg · Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg
Registry updated 2026-10-26
NCT07416526
A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A
Trial Treatment · Phase 3 · Hoffmann-La Roche
Haemophilia Comprehensive Care Centre, Parktown
Registry updated 2026-10-26
NCT05611801
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Trial Treatment · Phase 3 · Pfizer
Worthwhile Clinical Trials, Benoni · Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg
Registry updated 2026-10-14
NCT06003387
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
Trial Treatment · Phase 3 · CSL Behring
Haemophilia Comprehensive Care Centre, Johannesburg
Registry updated 2026-08-27
NCT05768386
A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)
Research · Phase 4 · BioMarin Pharmaceutical
Charlotte Maxeke Johannesburg Academic Hospital, Hemophilia Comprehensive Care Center, Johannesburg
Registry updated 2026-01-12

All Haemophilia trials and the map

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Haemophilia: open trials in South Africa

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)