Hepatitis B: open trials in United States

19 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT00001971
Evaluation of Patients With Liver Disease
Research · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT07031219
HIV/HBV/HCV Triple Screening in Primary Care
Trial Treatment · University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center, Dallas
Registry updated 2026-10-29
NCT07654283
Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions
Trial Treatment · Phase 2 · AusperBio Therapeutics Inc.
Institute of Human Virology, Baltimore · NYU Langone Health, New York · Stanford University School of Medicine, Redwood City · Texas Liver Institute, San Antonio
Registry updated 2026-10-29
NCT03025074
Blood Collection Biorepository for Liver Disease Research
Research · State University of New York at Buffalo
University at Buffalo, Buffalo General Medical Center, Buffalo
Registry updated 2026-10-08
NCT05832229
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
Trial Treatment · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Michigan, Ann Arbor · Cleveland Clinic, Cleveland · Duke Liver Center, Durham · University of California San Diego NAFLD Research Center, La Jolla · Keck Medical Center of USC, Los Angeles · LAC & USC Medical Center, Los Angeles · University of Miami Health System, Miami · Columbia University Iriving School of Medicine, New York · New York Presbyterian/Weill Cornell, New York · Virginia Commonwealth University, Richmond · Mayo Clinic, Rochester · UCSF Medical Center, San Francisco · UCSF - Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco
Registry updated 2026-09-28
NCT06084234
National Liver Cancer Screening Trial
Trial Treatment · Phase 4 · University of Texas Southwestern Medical Center
University of Michigan, Ann Arbor · Massachusetts General Hospital, Boston · University of North Carolina, Chapel Hill · Northwestern University, Chicago · The Cleveland Clinic, Cleveland · Case Western Reserve University, Cleveland · UT Southwestern Medical Center and Parkland Hospital, Dallas · Henry Ford Health System, Detroit · Baylor College of Medicine, Houston · Indiana University, Indianapolis · University of Southern California, Los Angeles · The Feinstein Institutes, Northwell Health, Inc., Manhasset · Hennepin Healthcare, Minneapolis · University of Minnesota, Minneapolis · University of Pennsylvania, Philadelphia · Stanford University, Redwood City · Virginia Commonwealth University, Richmond · Kaiser Permanente, Roseville · University of California San Francisco, San Francisco
Registry updated 2026-09-25
NCT07024641
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
Trial Treatment · Phase 1 · GigaGen, Inc.
Baltimore · Chandler · Huntington Beach · Iowa City · Lake Forest · Lenexa · Long Beach · Oakland · Peachtree Corners · Richmond · San Antonio · Webster
Registry updated 2026-09-25
NCT06680232
Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B
Trial Treatment · Phase 1 · Precision BioSciences, Inc.
Massachusetts General Hospital-Harvard University, Boston
Registry updated 2026-08-24
NCT07317687
Rapid HIV, Hep C, and Syphilis Screening in a Rural Street Medicine Clinic
Research · West Virginia University
WVU Department of Family Medicine - Eastern Division, Harpers Ferry
Registry updated 2026-08-13
NCT05181826
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
Research · Helio Genomics
Allina Health, Virginia Piper Cancer Institute, Coon Rapids · Liver Center of Texas, Dallas · Virginia Piper Cancer Institute Mercy Hospital-Unity Campus, Fridley · Methodist LeBonheur Healthcare, Memphis · VPCI Oncology Research, Minneapolis · Torrance Memorial Physician Network - Cancer Care, Redondo Beach · Methodist Hospital, Richardson
Registry updated 2026-07-10
NCT07658976
Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy
Trial Treatment · Phase 3 · HIV Prevention Trials Network
UCLA Vine Street Clinic, Los Angeles · Bronx Prevention Research Center CRS, The Bronx
Registry updated 2026-06-22
NCT07449091
Adaptability of an Undetectable = Untransmissible Model for HBV
Research · NYU Langone Health
NYU Langone Health, New York
Registry updated 2026-05-15
NCT07254208
A Long-term Observational Study in Participants Who Have Received PBGENE-HBV
Research · Precision BioSciences, Inc.
Massachusetts General Hospital-Harvard University, Boston
Registry updated 2026-04-22
NCT04843852
TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B
Trial Treatment · Phase 1 · University of Maryland, Baltimore
Institute of Human Virology, University of Maryland School of Medicine, Baltimore
Registry updated 2025-10-20
NCT06154278
Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
Trial Treatment · Phase 2 · University of Maryland, Baltimore
Institute of Human Virology, University of Maryland School of Medicine, Baltimore
Registry updated 2025-09-11
NCT00404989
Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.
Research · Syneos Health
Registry Coordinating Center, Wilmington
Registry updated 2025-04-01
NCT05417932
A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma
Trial Treatment · Phase 1/2 · SCG Cell Therapy Pte. Ltd.
New York, New York
Registry updated 2025-02-18
NCT06277037
Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)
Research · Arbutus Biopharma Corporation
Infectious Disease Care, Hillsborough · University of Miami Miller School of Medicine, Miami · Research and Education, Inc., San Diego
Registry updated 2024-11-27
NCT04588077
Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis
Trial Treatment · Phase 4 · Mercy Medical Center
Mercy Medical Center, Baltimore
Registry updated 2024-11-19

All Hepatitis B trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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