High blood pressure: open trials in United States

449 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT01730092
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
Research · National Institutes of Health Clinical Center (CC)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT05884190
Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
Trial Treatment · Yale University
Oishei Children's Hospital University at Buffalo, Buffalo · Yale New Haven Hospital, New Haven · University of Massachusetts Memorial Health, Worcester
Registry updated 2026-11-05
NCT06526195
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Trial Treatment · Abbott Medical Devices
Abington Memorial Hospital, Abington · New Mexico Heart Institute, Albuquerque · Piedmont Heart Institute, Atlanta · Piedmont Augusta Hospital, Augusta · Ascension Texas Cardiovascular, Austin · Massachusetts General Hospital, Boston · University of North Carolina at Chapel Hill, Chapel Hill · Medical University of South Carolina, Charleston · Carolinas Medical Center, Charlotte · University of Virginia Medical Center, Charlottesville · University of Chicago, Chicago · Christ Hospital, Cincinnati · The Cleveland Clinic Foundation, Cleveland · Prisma Health Midlands, Columbia · Baylor University Hospital, Dallas · Henry Ford Hospital, Detroit · Shands at the University of Florida, Gainesville · Spectrum Health Butterworth Hospital, Grand Rapids · Hackensack University Medical Center, Hackensack · Penn State Milton S. Hershey Medical Center, Hershey · CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston · Houston Methodist, Houston · UTHealth Memorial Hermann, Houston · St Vincent Hospital, Indianapolis · University of Iowa Hospitals & Clinics, Iowa City · Kansas University Medical Center, Kansas City · St. Luke's Hospital, Kansas City · University of Kentucky, Lexington · Baptist Health Medical Center, Little Rock · Norton Hospital, Louisville · North Shore University Hospital, Manhasset · Wellstar Kennestone Hospital, Marietta · The Stern Cardiovascular Foundation, Memphis · Aurora Medical Group, Milwaukee · Minneapolis Heart Institute, Minneapolis · Newark Beth Israel Medical Center, Newark · New York Presbyterian/Columbia University Medical Center, New York · Advocate Health & Hospitals Corporation, Oakbrook Terrace · Integris Baptist Medical Center, Oklahoma City · University of Nebraska Medical Center, Omaha · University of Pennsylvania, Philadelphia · University of Pittsburgh Medical Center (UPMC), Philadelphia · Banner-University Medical Center Phoenix, Phoenix · Allegheny General Hospital, Pittsburgh · The Heart Hospital Baylor Plano, Plano · Oregon Health Science University, Portland · Maine Medical Center, Portland · Virginia Commonwealth University, Richmond · Mayo Clinic, Rochester · University of Rochester Medical Center, Rochester · Sutter Medical Center, Sacramento · University of Utah Hospital, Salt Lake City · University of California at San Francisco, San Francisco · Scott & White Memorial Hospital, Temple · Montefiore Medical Center - Moses Campus, The Bronx · Saint Francis Hospital, Tulsa · Oklahoma Heart Institute at Utica, Tulsa · Washington Hospital Center, Washington D.C. · Cleveland Clinic Florida, Weston
Registry updated 2026-11-05
NCT07209527
Truway Diagnostic Tools in Primary Care
Trial Treatment · Early phase 1 · Truway Health, Inc.
Truway Health, Inc., New York
Registry updated 2026-11-05
NCT07918508
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
Trial Treatment · Florida International University
Caridad Center, Inc., Boynton Beach
Registry updated 2026-11-05
NCT07919405
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Trial Treatment · Phase 3 · Novo Nordisk A/S
Javara Inc. / Privia Medical Group Georgia LLC, Albany · Amarillo Med Spec LLP, Amarillo · Texas Diabetes & Endocrinology, P.A._Austin, Austin · Texas Diabetes & Endocrinology, Austin · Juno Research LLC, Bellaire · Graves Gibert Clinic, Bowling Green · Holston Medical Group Pc, Bristol · Northern Pines Hlth Ctr, PC, Buckley · Diab & Endo Assoc of Stark Co, Canton · Great Lakes Clinical Trials, Chicago · StudyMetrix Research, LLC, City of Saint Peters · Clinical Res Of W Florida Inc, Clearwater · John Muir Physicians Network, Concord · Hope Clin Res & Wellness, Conyers · Aurora FDRC Inc., Costa Mesa · Clinical Res Collaborative, Cumberland · North Texas Endocrine Center, Dallas · Baylor Jack and Jane Hamilton, Dallas · Velocity Clin Res, Dallas, Dallas · Aa Mrc Llc, Flint · Providence Medical Foundation, Fullerton · The Endocrine Center, Houston · Discovery MM Services, Inc, Houston · Midwest Inst For Clin Res, Indianapolis · Holston Medical Group., Kingsport · Radiance Clinical Research, Lampasas · DCOL Ctr for Clin Res, Longview · Monroe Biomedical Research, LLC, Louisville · Catalina Research Institute, LLC, Montclair · Koch Research, Morton · Clinical Research Associates, Nashville · Lynn Institute of Norman, Norman · Coastal Carolina Res Ctr, North Charleston · Renstar Medical Research, Ocala · Florida Institute for Clinical Research, Orlando · Desert Oasis Hlthcr Med Group, Palm Springs · Seacoast Kidney & Htn Specialists, Portsmouth · Accellacare_NC, Raleigh · Medication Management, LLC, Raleigh · Rainier Clin Res Ctr Inc, Renton · Endocrine Research Solutions, Inc, Roswell · Clinical Advancement Center, San Antonio · Northeast Clinical Research of San Antonio, San Antonio · N America Res Inst - San Dimas, San Dimas · Javara Inc./Privia Medical Group Georgia, LLC, Savannah · Consano Clinical Research, LLC, Shavano Park · Endeavor Health, Skokie · Evanston Premier Hlthcr Res, Skokie · Spartanburg Medical Research, Spartanburg · SIU Medicine, Springfield · Piedmont Healthcare, Inc., Statesville · Amicis Centers of Clinical Research, St Louis · Family Practice Center of Wadsworth Inc., Wadsworth · Chase Medical Research, LLC, Waterbury · Iowa Diabetes Research, West Des Moines · Great Lakes Medical Research, Westfield · Southgate Medical Group, LLP, West Seneca
Registry updated 2026-11-05
NCT07142356
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Trial Treatment · Phase 2 · Retension Pharmaceuticals. Inc.
Alexander City · Asheboro · Bellaire · Birmingham · Bloomfield Hills · Boca Raton · Boston · Charleston · Charlotte · Cincinnati · Dallas · Decatur · Glendale · Indianapolis · Jacksonville · Las Vegas · Lawrenceville · Leesburg · Maitland · Methuen · Monroe · Munster · New Orleans · North Charleston · Orlando · Overland · Pasadena · Peachtree Corners · Plano · Port Orange · San Antonio · San Diego · San Jose · Sugar Land · Tampa · The Bronx · Tucson · Tulsa · Ventura · Vienna · Waterbury · West Hills
Registry updated 2026-11-04
NCT07602166
Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans
Trial Treatment · Phase 2 · Vanderbilt University Medical Center
Vanderbilt University Medical Center, Nashville
Registry updated 2026-11-04
NCT07915752
A MOST Framework Trial Evaluating the MOst effectiVe Exercise Types for Blood Pressure Control
Trial Treatment · Northwestern University
Northwestern University, Chicago
Registry updated 2026-11-04
NCT07915882
Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
Trial Treatment · Michael Incze
University Of Utah Health, Salt Lake City
Registry updated 2026-11-04
NCT01712620
Spironolactone for Pulmonary Arterial Hypertension
Trial Treatment · Phase 2 · National Institutes of Health Clinical Center (CC)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-03
NCT05377320
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study
Research · Medical College of Wisconsin
Froedtert & the Medical College of Wisconsin, Milwaukee
Registry updated 2026-11-03
NCT06911632
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Trial Treatment · Tempus AI
University of New Mexico, Albuquerque · University of Michigan - Michigan Medicine, Ann Arbor · University of Alabama at Birmingham, Birmingham · Willis Knighton Health, Bossier City · Brigham and Women's Hospital, Boston · University of Buffalo, Buffalo · Medical University of South Carolina, Charleston · University of Illinois Health, Chicago · Northwestern University, Chicago · University Hospitals Cleveland Medical Center*, Cleveland · Baylor University Medical Center, Dallas · National Jewish Health, Denver · Hannibal Regional Healthcare System, Hannibal · Baylor College of Medicine, Houston · The University of Texas Health Science Center Houston, Houston · Houston Methodist Hospital, Houston · Community Health Network, Indianapolis · Indiana University Health Methodist Hospital, Indianapolis · University of Mississippi Medical Center, Jackson · University of Tennessee, Knoxville · University of Kentucky, Lexington · University of Arkansas, Little Rock · University of Minnesota, Minneapolis · West Virginia University Hospital, Morgantown · Weill Cornell University Medical College, New York · University of Oklahoma, Oklahoma City · CHI Health Creighton University Medical Center-Bergan Mercy, Omaha · AdventHealth Orlando, Orlando · Thomas Jefferson University, Philadelphia · Temple University Of the Commonwealth System of Higher Education, Philadelphia · Dignity Health - St. Joseph's Hospital and Medical Center-Norton Thoracic Institute, Phoenix · Banner University Medical Center, Phoenix · Renown Regional Medical Center, Reno · Virginia Commonwealth University, Richmond · HCA Riverside Community Hospital, Riverside · Corewell Health, Royal Oak · University of Utah, Salt Lake City · HCA Research Institute - Methodist Hospital, San Antonio · Louisiana State University Health Shreveport, Shreveport · Mercy Hospital Springfield, Springfield · Southeastern Research Center, Winston-Salem
Registry updated 2026-11-03
NCT07783802
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Trial Treatment · Phase 2 · Eli Lilly and Company
Omega Research Orlando, Altamonte Springs · Rochester Clinical Research - Buffalo, Buffalo · Velocity Clinical Research, Cincinnati, Springdale, Cincinnati · American Research Institute, Cutler Bay · Horizon Clinical Research Group, Cypress · Revival Research Institute, LLC, Dearborn · K2 Medical Research - Foxborough, Foxborough · Thrive Clinical Research Group, Glendora · Cardiovascular Specialists of Willowbrook, Houston · Heart Center Research, LLC, Huntsville · Franciscan Physician Network, Indiana Heart Physicians, Indianapolis · Texas Cardiology Associates of Houston, Kingwood · Palm Research Center Tenaya, Las Vegas · Excel Clinical Research, LLC, Las Vegas · Accellacare - DuPage, Lombard · K2 Medical Research - Maitland, Maitland · Carient Heart & Vascular - Manassas, Manassas · Texas Institute of Cardiology PA, McKinney · Revival Research Institute, LLC, McKinney · Monroe Biomedical Research - Charleston, North Charleston · Ogden Clinic - Canyon View, Ogden · Olive Branch Family Medical Center, Olive Branch · Florida Institute For Clinical Research, LLC, Orlando · Carient Heart and Vascular LLC-Reston, Reston · CHEAR Center LLC, The Bronx · Eclipse Clinical Research, Tucson · Pima Heart, Tucson · Suburban Research Associates, West Chester · North Georgia Clinical Research, Woodstock · Cardiology Consultants of Philadelphia Yardley, Yardley
Registry updated 2026-11-03
NCT07913074
A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.
Trial Treatment · Phase 2 · Tavo Biotherapeutics
Global Research Management, Inc, Glendale · Piedmont Eye Center, Lynchburg · Eye Research Foundation Inc., Newport Beach
Registry updated 2026-11-03
NCT05587712
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Children's Hospital Colorado ( Site 1609), Aurora · Cincinnati Children's Hospital Medical Center ( Site 1602), Cincinnati · The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 1606), Los Angeles · Children's Wisconsin ( Site 1610), Milwaukee · Monroe Carell Jr. Children's Hospital ( Site 1601), Nashville · Stanford University School of Medicine ( Site 1603), Palo Alto · Children's Hospital of Philadelphia (CHOP) ( Site 1608), Philadelphia · UCSF Benioff Children's Hospital San Francisco ( Site 1611), San Francisco · Seattle Children's Hospital ( Site 1605), Seattle · Children's National Medical Center ( Site 1600), Washington D.C.
Registry updated 2026-11-02
NCT07247162
Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome
Trial Treatment · Phase 4 · RECORDATI GROUP
Diabetes And Endocrinology Associates Of Stark County, Inc., Canton · NOLA Care, LLC, Jacksonville · Texas Valley Clinical Research, Weslaco
Registry updated 2026-11-02
NCT07848828
Autonomic and Renal Contributions to Hypertension With ADT
Trial Treatment · Phase 4 · Virginia Commonwealth University
Virginia Commonwealth University, Richmond
Registry updated 2026-11-02
NCT07910773
Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot Trial
Trial Treatment · University of California, San Francisco
Satellite Healthcare - Daly City, San Francisco · Zuckerberg San Francisco General Hospital, San Francisco · Satellite Healthcare - San Francisco Geary, San Francisco
Registry updated 2026-11-02
NCT06402968
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Research · Zeenat Qureshi Stroke Institute
Cleveland Clinic Akron General, Akron · Albany Medical Center, Albany · Augusta University-Neuroscience Center, Augusta · Cleveland Clinic Foundation, Cleveland · UT Southwestern Medical Center, Dallas · William P. Clements Jr. University Hospital, Dallas · Frederick Memorial Hospital, Frederick · University of California, Irvine · Antelope Valley Medical Center, Lancaster · Wellstar Kennestone Regional Medical Center, Marietta · Community Hospital, Munster · Icahn School of Medicine at Mount Sinai, New York · Stanford Medical Center (Stanford Health Care), Palo Alto · Mayo Clinic Hospital, Saint Marys Campus, Rochester · CentraCare - St. Cloud Hospital, Saint Cloud · University of Texas Health Science Center San Antonio, San Antonio · Cleveland Clinic Martin North Hospital, Stuart · University of South Florida, Tampa · ProMedica Toledo Hospital, Toledo · Cleveland Clinic Florida, Weston · University of Michigan Health - West, Wyoming
Registry updated 2026-10-30
NCT07123779
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
Trial Treatment · Phase 1/2 · 35Pharma Inc., a GSK company
Dallas · Greenville · Kansas City
Registry updated 2026-10-30
NCT07143448
A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults
Trial Treatment · Phase 1/2 · 35Pharma Inc., a GSK company
Boston · Providence · Tampa
Registry updated 2026-10-30
NCT07637110
Dry Weight Reduction Intervention Via Extra Ultrafiltration
Trial Treatment · University of Washington
Northwest Kidney Centers, Seattle
Registry updated 2026-10-30
NCT00001853
Diabetes and Heart Disease Risk in Blacks
Research · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT02417740
Natural History of Noncirrhotic Portal Hypertension
Research · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29

All High blood pressure trials and the map

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