Lung cancer: open trials in Australia

164 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT05384626
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Trial Treatment · Phase 1/2 · Nuvalent Inc.
Peter MacCallum Cancer Centre, Melbourne · Royal North Shore Hospital, Sydney · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-11-06
NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Trial Treatment · Phase 3 · Amgen
Cancer Research South Australia, Adelaide · Campbelltown Hospital, Campbelltown · Concord Repatriation General Hospital, Concord · Nepean Cancer Centre, Kingswood · Peter MacCallum Cancer Centre, Melbourne · The Alfred Hospital, Melbourne · Port Macquarie Base Hospital, Port Macquarie · GenesisCare -North Shore Oncology, St Leonards · Toowoomba Hospital, Toowoomba · Calvary Mater Newcastle Hospital, Waratah · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-11-06
NCT06284317
A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
Trial Treatment · Phase 3 · ETOP IBCSG Partners Foundation
Flinders Medical Centre, Bedford Park · Eastern Health, Box Hill · Chris O'Brien Lifehouse, Camperdown · Royal Hobart Hospital, Hobart · Alfred Hospital, Melbourne · Sir Charles Gairdner Hospital, Nedlands · Peter MacCallum Cancer Centre, Parkville · Nepean Hospital, Penrith · Royal North Shore Hospital, St Leonards · Princess Alexandra Hospital, Woolloongabba
Registry updated 2026-11-06
NCT06881784
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Trial Treatment · Phase 3 · Revolution Medicines, Inc.
Blacktown Medical Oncology Research, Blacktown Hospital, Blacktown · Chris O'Brien Lifehouse, Camperdown · St. George Private Hospital Clinical Trials Unit, Kogarah · Alfred House, Melbourne · Sir Charles Gairdner Hospital, Perth · Mater Misericordiae Limited, South Brisbane · Calvary Mater Newcastle, Waratah
Registry updated 2026-11-06
NCT07659782
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
Trial Treatment · Phase 2 · Verastem, Inc.
ICON Cancer Centre South Brisbane, Brisbane · Chris O'Brien Lifehouse, Camperdown · Macquarie University Hospital, Sydney
Registry updated 2026-11-06
NCT07699328
A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer
Trial Treatment · Phase 1/2 · Voronoi, Inc
Southern Oncology Clinical Research Unit, Bedford Park · Monash Medical Centre Clayton, Clayton
Registry updated 2026-11-06
NCT05789082
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Concord Repatriation General Hospital, Concord · Alfred Health, Melbourne · Peter MacCallum Cancer Centre, Melbourne
Registry updated 2026-11-05
NCT06793215
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Hoffmann-La Roche
Sunshine Coast University Hospital, Birtinya · Monash Health, Clayton · Kinghorn Cancer Centre, Darlinghurst · Austin Health, Heidelberg · Royal Hobart Hospital, Hobart · Liverpool Hospital, Liverpool · Peter MacCallum Cancer Centre, Melbourne · Calvary Mater Newcastle, Waratah
Registry updated 2026-11-05
NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · Pfizer
Grampians Health, Ballarat · Royal Hobart Hospital, Hobart · Calvary Mater Newcastle, Waratah · Westmead Hospital, Westmead
Registry updated 2026-11-05
NCT07361497
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Grampians Health, Ballarat Central · Lyell McEwin Hospital, Elizabeth Vale · Northern Hospital, Epping · Gosford Hospital, Gosford · Joondalup Health Campus, Joondalup · Nepean Hospital, Penrith · Westmead Hospital, Westmead
Registry updated 2026-11-05
NCT07491497
A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC
Trial Treatment · Phase 1/2 · TRIANA Biomedicines, Inc.
Peter MacCallum Cancer Centre, Melbourne · Royal North Shore Hospital, Sydney · Westmead Hospital, Westmead
Registry updated 2026-11-05
NCT06119581
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · Eli Lilly and Company
Royal Adelaide Hospital, Adelaide · ICON Cancer Centre Wesley, Auchenflower · Ballarat Health Services, Ballarat Central · Sunshine Coast University Hospital, Birtinya · Gosford Hospital, Gosford · Mackay Base Hospital, Mackay · St Vincent's Hospital, Melbourne · Sir Charles Gairdner Hospital, Perth · Goulburn Valley Health, Shepparton · Gold Coast University Hospital, Southport · The Townsville Hospital, Townsville
Registry updated 2026-11-04
NCT06400472
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
Cancer Research SA, Adelaide · Icon Cancer Centre South Brisbane, QLD
Registry updated 2026-11-04
NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 3 · Bayer
NSW Health - Blacktown Hospital, Blacktown · University of the Sunshine Coast, Buderim · Concord Repatriation General Hospital - Medical Oncology Clinical Trials Unit, Concord · Austin Hospital - Olivia Newton John Cancer Research Institute, Heidelberg · Toowoomba Hospital Oncology Clinical Trials, Toowoomba · Calvary Mater Hospital Newcastle - Oncology, Waratah
Registry updated 2026-11-04
NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
St Vincent's Hospital, Darlinghurst · Linear Clinical Research, Nedlands
Registry updated 2026-11-04
NCT06706076
A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations
Trial Treatment · Phase 1/2 · BlossomHill Therapeutics
Austin Health, Heidelberg · Peter MacCallum Cancer Centre, Melbourne
Registry updated 2026-11-04
NCT06890598
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Eli Lilly and Company
ICON Cancer Centre Wesley, Auchenflower · Sunshine Coast University Hospital, Birtinya · Austin Health, Heidelberg · Icon Cancer Centre Kurralta Park, Kurralta Park · Tamworth Hospital, North Tamworth · Sir Charles Gairdner Hospital, Perth · Goulburn Valley Health, Shepparton · Latrobe Regional Health, Traralgon
Registry updated 2026-11-04
NCT06060613
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Obsidian Therapeutics, Inc.
Melanoma Institute of Australia, Wollstonecraft
Registry updated 2026-11-03
NCT06170788
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Grampians Health-Medical Oncology (Site 3001), Ballarat Central · Northern Hospital (Site 3003), Epping · Peninsula University Hospital (Site 3004), Frankston · Port Macquarie - Mid North Coast Cancer Institute-Medical Oncology (Site 3002), Port Macquarie · Westmead Hospital (Site 3000), Westmead
Registry updated 2026-11-03
NCT06667908
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 2 · Johnson & Johnson Enterprise Innovation Inc.
Chris O'Brien Lifehouse, Camperdown · Royal Brisbane and Women's Hospital, Herston · Sir Charles Gairdner Hospital, Nedlands · Macquarie University, North Ryde · Royal Melbourne Hospital, Parkville
Registry updated 2026-11-03
NCT07288177
Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer
Trial Treatment · Phase 2 · Genmab
St Andrews Medical Centre, Adelaide · Blacktown Hospital, Blacktown · Chris O'Brien Lifehouse, Camperdown · St Vincent's Hospital Melbourne, Fitzroy · Icon Cancer Centre Hobart, Hobart · Icon Cancer Care - Townsville, Hyde Park · Icon Cancer Centre Townsville ICON Cancer Care - Townsville, Hyde Park · St George Hospital, Kogarah · St John of God Murdoch Hospital, Murdoch · Sir Charles Gairdner Hospital, Nedlands · GenesisCare North Shore, Saint Leonards
Registry updated 2026-11-03
NCT07365319
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Peninsula and Southeast Oncology (PASO) Medical, Frankston · Cancer Care Northern Beaches, Frenchs Forest · Sunshine Hospital - Western Health, Saint Albans · Calvary Mater Newcastle Hospital, Waratah
Registry updated 2026-11-03
NCT07660055
Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Darlinghurst
Registry updated 2026-11-03
NCT06305962
177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors
Trial Treatment · Early phase 1 · Radiopharm Theranostics, Ltd
Cancer Research SA (CRSA), Adelaide · Gosford Hospital, Gosford · Nepean Hospital, Kingswood · GenesisCare Murdoch, Murdoch · Gold Coast University Hospital, Southport · Wollongong Hospital, Wollongong
Registry updated 2026-11-02
NCT06712316
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)
Trial Treatment · Phase 2/3 · BioNTech SE
Cancer Research SA (CRSA), Adelaide · Royal Adelaide Hospital, Adelaide · Flinders Medical Centre, Bedford Park · Cairns Hospital, Cairns · Dubbo Hospital, Dubbo · Peninsula & South Eastern Haematology and Oncology Group, Frankston · Joondalup Health Campus, Joondalup · Icon Cancer Centre Kurralta Park, Kurralta Park · Peter MacCallum Cancer Centre, Melbourne · Monash University - Monash Health -Monash Medical Centre, Melbourne · Central West Cancer Care Centre, Orange · Clinical Trial Center-Tasman Oncology Research Ltd, Southport · Western Health Sunshine Hospital, St Albans · ICON Cancer Care - Townsville, Townsville · Cancer Care Wollongong Pty Limited, Wollongong
Registry updated 2026-11-02

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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