Lung cancer: open trials in Bulgaria

23 open trials have a site in Bulgaria. Registry data; only the trial team decides who can take part.

NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Trial Treatment · Phase 3 · Amgen
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Umhat Sveta Marina - Pleven OOD, Pleven · Mbal Za Zhensko Zdrave Nadezhda OOD, Sofia · Acibadem City Clinic Tokuda University Hospital EAD, Sofiya
Registry updated 2026-11-06
NCT07284121
A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice
Research · Hoffmann-La Roche
Multiprofile Hospital for Active Treatment Uni Hospital, Panagyurishte · Complex Oncological Center-Ruse EOOD, Rousse · MBAL Serdika EOOD, Sofia · UMHAT "Sv. Ivan Rilski", EAD, Sofia · Tokuda Hospital, Sofia · MHAT SofiaMed, Sofia · UMHAT Tsaritsa Yoanna - ISUL, Sofia
Registry updated 2026-11-06
NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · Pfizer
Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo · Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Mbal Za Zhensko Zdrave Nadezhda OOD, Sofia · University Specialized Hospital For Active Treatment In Oncology EAD, Sofiya · MBAL Trakia EOOD, Stara Zagora
Registry updated 2026-11-05
NCT07361497
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo · Complex Oncology Center Ruse EOOD, Ruse · Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD, Sofia · University Multidisciplinary Hospital For Active Treatment Sveta Ekaterina EAD, Sofia · Diagnostics And Consultation Center Convex Ltd., Sofiya
Registry updated 2026-11-05
NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 3 · Bayer
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Multi-profile Hospital for Active Treatment Heart and Brain EAD, Pleven · Complex Oncological Center - Plovdiv, EOOD, Plovdiv · MBAL Serdika Ltd., Sofia · University Specialized Hospital For Active Treatment In Oncology EAD, Sofiya · Multispecialty hospital for active treatment Sveta Sofia EOOD, Sofiya · UMHAT Sofiamed OOD, Sofiya · University Hospital St Marina Varna, Varna
Registry updated 2026-11-04
NCT07365319
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Mbal Za Zhensko Zdrave Nadezhda OOD, Sofia
Registry updated 2026-11-03
NCT06712316
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)
Trial Treatment · Phase 2/3 · BioNTech SE
Complex Oncological Center - Plovdiv, EOOD, Plovdiv · Complex Oncology Center Ruse EOOD, Ruse · University Multidisciplinary Hospital For Active Treatment Sveta Ekaterina EAD, Sofia · Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD, Sofia · Mbal Za Zhensko Zdrave Nadezhda OOD, Sofia
Registry updated 2026-11-02
NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Trial Treatment · Phase 2/3 · Mirati Therapeutics Inc.
Multiprofile Hospital For Active Treatment "Dr. Tota Venkova" AD, Gabrovo · Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo · Complex Oncological Center - Plovdiv, EOOD, Plovdiv · University Multiprofile Hospital For Active Treatment St. Ivan Rilski EAD, Sofia
Registry updated 2026-10-30
NCT06623422
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Multi-profile Hospital for Active Treatment Heart and Brain EAD, Pleven · Complex Oncology Center Ruse EOOD, Ruse
Registry updated 2026-10-30
NCT04928846
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AbbVie
Complex Oncology Center Burgas EOOD, Burgas · Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Complex Oncological Center - Plovdiv, EOOD, Plovdiv · UMHAT Sofiamed OOD, Sofiya · University Hospital St Marina Varna, Varna
Registry updated 2026-10-29
NCT07472517
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
Trial Treatment · Phase 3 · Boehringer Ingelheim
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Multi-profile Hospital for Active Treatment Heart and Brain EAD, Pleven · Acibadem City Clinic Tokuda University Hospital EAD, Sofiya
Registry updated 2026-10-28
NCT06875310
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Trial Treatment · Phase 3 · Mirati Therapeutics Inc.
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Complex Oncology Center Ruse EOOD, Ruse · Multiprofile Hospital for Active Treatment Serdikamed EOOD, Sofia · MBAL Trakia EOOD, Stara Zagora
Registry updated 2026-10-27
NCT06345729
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Multi-profile Hospital for Active Treatment Heart and Brain EAD, Pleven · Medical Centre Futuremeds EOOD, Plovdiv · Complex Oncological Center - Plovdiv, EOOD, Plovdiv · MBAL Serdika Ltd., Sofia
Registry updated 2026-10-26
NCT07063745
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo · Complex Oncology Center Ruse EOOD, Ruse · University Multidisciplinary Hospital For Active Treatment Sveta Ekaterina EAD, Sofia · Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD, Sofia · MBAL Trakia EOOD, Stara Zagora
Registry updated 2026-10-23
NCT07361510
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Complex Oncology Center Ruse EOOD, Ruse · Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD, Sofia · University Multidisciplinary Hospital For Active Treatment Sveta Ekaterina EAD, Sofia · Diagnostics And Consultation Center Convex Ltd., Sofiya
Registry updated 2026-10-23
NCT07099898
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]
Trial Treatment · Phase 3 · GlaxoSmithKline
Pleven · Plovdiv · Rousse · Sofia
Registry updated 2026-10-20
NCT03460977
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Trial Treatment · Phase 1 · Pfizer
Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo · Complex Oncological Center - Plovdiv, EOOD, Plovdiv · Complex Oncology Center Ruse EOOD, Ruse · Complex Oncology Center Vratsa EOOD, Vratsa
Registry updated 2026-10-15
NCT07625644
BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
Trial Treatment · Phase 3 · SystImmune Inc.
MHAT Dr. Tota Venkova, Gabrovo · MHAT Heart and brain, Pleven · MHAT Pulmed, Plovdiv · Medical Centre FutureMeds, Plovdiv · MHAT Serdikamed, Sofia · UMHAT Sveti Ivan Rilski, Sofia
Registry updated 2026-10-15
NCT06758401
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
Trial Treatment · Phase 3 · Pfizer
University Multiprofile Hospital For Active Treatment Burgas AD, Burgas · Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Medical Centre Futuremeds EOOD, Plovdiv · Mbal Za Zhensko Zdrave Nadezhda OOD, Sofia · University Specialized Hospital For Active Treatment In Oncology EAD, Sofiya · Acibadem City Clinic Tokuda University Hospital EAD, Sofiya
Registry updated 2026-09-25
NCT06868277
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · AstraZeneca
Comprehensive Cancer Center - Burgas, EEOD, Burgas · Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Tokuda Hospital, Sofia · University Specialized Hospital For Active Treatment In Oncology EAD, Sofiya · Multispecialty hospital for active treatment Sveta Sofia EOOD, Sofiya
Registry updated 2026-09-25
NCT05303532
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study with Durvalumab
Trial Treatment · Phase 3 · Astrazeneca AB
Multiprofile Hospital For Active Treatment Serdicamed EOOD, Sofia · University Multiprofile Hospital For Active Treatment St. Ivan Rilski EAD, Sofia
Registry updated 2026-09-08
NCT05882058
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers
Trial Treatment · Phase 2 · Boehringer Ingelheim
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd., Panagyurishte · Multi-profile Hospital for Active Treatment Heart and Brain EAD, Pleven
Registry updated 2026-07-23
NCT07130916
A Study of Aumolertinib in European Participants With Non-Small Cell Lung Cancer
Trial Treatment · Phase 1 · Jiangsu Hansoh Pharmaceutical Co., Ltd.
MHAT "Sveta Sofia" Departmet of Medical Oncology Bulgaria Blvd, Sofia
Registry updated 2025-08-19

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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