Lung cancer: open trials in Brazil

68 open trials have a site in Brazil. Registry data; only the trial team decides who can take part.

NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Trial Treatment · Phase 3 · Amgen
Fundacao pio xII Barretos, Barretos · Centro de Tratamento Oncologico - Cto, Belém · Nucleo de Ensino Pesquisa e Inovacao Mario Penna, Belo Horizonte · Cenantron Centro Avançado de Tratamento Oncologico Ltda, Belo Horizonte · Hospital Sirio Libanes Brasilia, Brasília · Oncoclinicas Onco Vida Distrito Federal, Brasília · Hospital Evangelico de Cachoeiro de Itapemirim, Cachoeiro de Itapemirim · Associação Beneficente de Canoas, Canoas · Clínica de Neoplasias Litoral, Itajaí · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Nossa Senhora da Conceição, Porto Alegre · Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul, Porto Alegre · Irmandade Da Santa Casa de Misericordia de Porto Alegre, Porto Alegre · Instituto Medicina Integral Imip, Recife · Oncoclinicas Rio de Janeiro S A, Rio de Janeiro · Nucleo de Oncologia da Bahia, Salvador · Centro de pesquisa em oncologia Hospital Ana Nery, Santa Cruz do Sul · Santa Casa de Misericordia de Santos - Iscms, Santos · Hospital de Base de Sao Jose do Rio Preto, São José do Rio Preto · Instituto de Ensino e Pesquisa Sao Lucas Iep Sao Lucas, São Paulo · Fundacao Antonio Prudente, São Paulo · Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo · Beneficencia Portuguesa de Sao Paulo - Bp, São Paulo · Instituto Cancer Sao Paulo Icesp, São Paulo
Registry updated 2026-11-06
NCT05789082
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Hospital de Cancer de Barretos, Barretos · Instituto do Cancer do Estado de Sao Paulo - ICESP, São Paulo
Registry updated 2026-11-05
NCT06793215
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Hoffmann-La Roche
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · Centro Integrado de Oncologia de Curitiba, Curitiba · Crio - Centro Regional Integrado de Oncologia, Fortaleza · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Nossa Senhora da Conceição, Porto Alegre · Irmandade Da Santa Casa de Misericordia de Porto Alegre, Porto Alegre · Instituto do Cancer do Estado de Sao Paulo - ICESP, São Paulo
Registry updated 2026-11-05
NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · Pfizer
Hospital Santo Antonio, Blumenau · Hospital de Clinicas de Passo Fundo, Passo Fundo · IBCC - Núcleo de Pesquisa e Ensino, São Paulo · Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo · IBCC - Instituto Brasileiro de Controle do Câncer, São Paulo
Registry updated 2026-11-05
NCT07361497
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · Liga Norte Riograndense Contra o Cancer, Natal · Hospital de Clinicas de Porto Alegre, Porto Alegre · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto · Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo · Vencer Centro de Pesquisa LTDA, Teresina
Registry updated 2026-11-05
NCT06119581
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · Eli Lilly and Company
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · Hospital Tacchini, Bento Gonçalves · Hospital São Domingos, Bequimão · Sirio-Libanes Brasilia - Centro de Oncologia - Asa Sul, Brasília · Hospital Universitário Evangélico Mackenzie, Curitiba · Centro de Pesquisa Clínica do Instituto do Câncer do Ceará, Fortaleza · ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijuí · Hospital Brasilia, Lago Sul · Hospital de Cancer de Londrina, Londrina · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Sao Lucas da PUCRS, Porto Alegre · Oncominas, Pouso Alegre · Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rio de Janeiro · Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA, Rio de Janeiro · Instituto D'Or Pesquisa e Ensino, Rio de Janeiro · Clinica Amo - Rio Vermelho, Salvador · Faculdade de Medicina do ABC, Santo André · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto · COE Ensino e Pesquisa, São José dos Campos · Hospital Sirio Libanes, São Paulo · Centro Paulista de Oncologia Clínica, São Paulo · Instituto de Assistência Médica ao Servidor Público Estadual - IAMSPE/HSPE-FMO Conhecer Centro de Oncolog -T, São Paulo · Hospital Santa Catarina - Paulista, São Paulo · Hospital BP, São Paulo · Núcleo de Pesquisa Clínica da Rede São Camilo, São Paulo · Hospital Paulistano, São Paulo · Instituto D'Or de Pesquisa e Ensino (IDOR), São Paulo · Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo · CEDOES, Vitória
Registry updated 2026-11-04
NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 3 · Bayer
NAIC - Instituto do Câncer, Bauru · Centro de Pesquisa da Clínica de Oncologia Reichow, Blumenau · Centro Paulista de Oncologia (CPO) - Sao Paulo - Faria Lima, Brasília · Pronutrir Fortaleza - CE, Fortaleza · Fundacao Pio XII - Hospital de Cancer de Barretos, Jaú · Liga Norte Riograndense Contra o Cancer | Centro de Pesquisa Clínica, Natal · Rede DoR Recife - PE, Recife · Hospital de Base | Funfarme - Centro Integrado de Pesquisa - Cardiologia, São José do Rio Preto · A Beneficencia Portuguesa de Sao Paulo - Hospital BP Mirante, São Paulo · Hospital Sirio Libanes, São Paulo · Hospital Sirio-Libanes (HSL) - Centro de Oncologia - Brasilia, São Paulo · Irmandade Santa Casa de Misericordia de Porto Alegre | Oncology, São Paulo
Registry updated 2026-11-04
NCT06890598
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Eli Lilly and Company
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · CTO - Centro de Tratamento Oncológico, Belém · Oncocentro de Minas Gerais, Belo Horizonte · Hospital Tacchini, Bento Gonçalves · Centro de Pesquisa Sao Lucas, Campinas · Centro de Pesquisa Clínica do Instituto do Câncer do Ceará, Fortaleza · Hospital de Cancer de Londrina, Londrina · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Sao Lucas da PUCRS, Porto Alegre · Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA, Rio de Janeiro · Instituto D'Or Pesquisa e Ensino, Rio de Janeiro · Centro Paulista de Oncologia Clínica, São Paulo · Instituto D'Or de Pesquisa e Ensino (IDOR), São Paulo · Hospital Sirio Libanes, São Paulo · Hospital Santa Catarina - Paulista, São Paulo · Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo
Registry updated 2026-11-04
NCT05498428
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Trial Treatment · Phase 2 · Janssen Research & Development, LLC
Fundacao Pio XII, Barretos · PERSONAL Oncologia de Precisao e Personalizada, Belo Horizonte · Hospital do Câncer de Londrina, Londrina · Hospital Moinhos de Vento, Porto Alegre · IDOR - Regional Rio de Janeiro, Rio de Janeiro · IDOR - Regional Bahia, Salvador · Fundacao Antonio Prudente A C Camargo Cancer Center, São Paulo · Hospital Alemão Oswaldo Cruz, São Paulo · Impar Servicos Hospitalares SA Hospital Nove de Julho, São Paulo
Registry updated 2026-11-03
NCT06170788
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Fundação Pio XII - Hospital de Câncer de Barretos (Site 0402), Barretos · Irmandade da Santa Casa de Misericórdia de Porto Alegre (Site 0409), Porto Alegre · Instituto Nacional de Câncer - INCA (Site 0405), Rio de Janeiro · Clinica Viver (Site 0400), Santa Maria · Fundação Faculdade Regional de Medicina de São José do Rio Preto (Site 0406), São José do Rio Preto · Núcleo de Pesquisa Clínica da Rede São Camilo (Site 0401), São Paulo
Registry updated 2026-11-03
NCT06667908
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 2 · Johnson & Johnson Enterprise Innovation Inc.
Fundacao Pio XII, Barretos · Sociedade Beneficente de Senhoras Hospital Sirio Libanes, São Paulo · Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo
Registry updated 2026-11-03
NCT07365319
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Hospital Evangelico de Cachoeiro de Itapemirim, Cachoeiro de Itapemirim · Oncoclínicas Rio de Janeiro, Rio de Janeiro · Nucleo de Oncologia da Bahia, Salvador
Registry updated 2026-11-03
NCT06712316
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)
Trial Treatment · Phase 2/3 · BioNTech SE
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · CIONC-Centro Integrado de Oncologia de Curitiba, Curitiba · Centro Regional Integrado de Oncologia, Fortaleza · ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijuí · Clinica de Neoplasias Litoral LTDA / Catarina Pesquisa Clínica, Itajaí · Bruno Born Hospital, Lajeado · Instituto de Cancer de Londrina - Hospital do Cancer de Londrina - HCL, Londrina · Liga Norte Riograndense Contra o Cancer - CECAN, Natal · Hospital Sao Vicente de Paulo (HSVP), Passo Fundo · Hospital Nossa Senhora da Conceição, Porto Alegre · Irmandade Santa Casa de Misericordia de Porto Alegre, Porto Alegre · Centro Clinico do Hospital Sao Lucas da PUCRS, Porto Alegre · Centro Gaucho Integrado de Oncologia e Hematologia - Hospital Mae de Deus/AESC, Porto Alegre · Oncoclinicas Rio de Janeiro S.A (Centro de Tratamento de Tumores Botafogo), Rio de Janeiro · OC Oncoclínicas - Núcleo de Oncologia da Bahia-Ondina (OC Oncoclinicas-NOB Ondina), Salvador · CEON Pesquisas, São Caetano do Sul · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto - Hospital de Base de Sao Jose do Rio Preto, São José do Vale do Rio Preto · IEP São Lucas, São Paulo · IEP Sao Lucas Instituto de Ensino e Pesquisa Sao Lucas, São Paulo · Associacao Feminina de Educacao e Combate ao Cancer(AFECC) - Hospital Santa Rita, Vitória
Registry updated 2026-11-02
NCT07195695
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Trial Treatment · Phase 3 · Boehringer Ingelheim
Hospital de Amor, Barretos · NewData Clinical Research - Maceió, Maceió · Centro de Pesquisa Oncology Natal, Natal · Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa, Porto Alegre · CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia, Santo André · A.C. Camargo, São Paulo · Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo
Registry updated 2026-11-02
NCT07431827
MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Hospital Madre Teresa (Site 0420), Belo Horizonte · PRONUTRIR (Site 0425), Fortaleza · Real Hospital Portugues (Site 0418), Recife · Faculdade de Medicina do ABC (Site 0415), Santo André · Hospital Alemao Oswaldo Cruz (Site 0416), São Paulo · Instituto do Câncer Brasil - Unidade Taubaté (Site 0424), Taubaté · AFECC ASSOCIACAO FEMININA EDUCACAO COMBATE CANCER (Site 0414), Vitória
Registry updated 2026-11-02
NCT07554339
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Fundação Pio XII - Hospital de Câncer de Barretos (Site 0401), Barretos · CEPON (Site 0413), Florianópolis · CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA (Site 0406), Fortaleza · AFECC ASSOCIACAO FEMININA EDUCACAO COMBATE CANCER (Site 0416), Vitória
Registry updated 2026-11-02
NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Trial Treatment · Phase 2/3 · Mirati Therapeutics Inc.
Local Institution - Unk060, Barretos · Fundação Pio XII - Hospital de Câncer de Barretos - Hospital de Amor, Barretos · CEPON - Centro de Pesquisas Oncologicas, Florianópolis · Local Institution - Unk002, Ijuí · Local Institution - Unk050, Lajeado · Liga Contra o Câncer - Centro Avançado de Oncologia, Natal · Local Institution - Unk015, Porto Alegre · Hospital Nossa Senhora da Conceição, Porto Alegre · Local Institution - 007-5052, Porto Alegre · Local Institution - Unk003, Rio de Janeiro · Hospital Santa Izabel, Salvador · Local Institution - Unk019, São José do Rio Preto · Local Institution - Unk074, São Paulo
Registry updated 2026-10-30
NCT06623422
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Hospital de Amor - Barretos (Site 2511), Barretos · Hospital Tacchini (Site 2506), Bento Gonçalves · CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA (Site 2502), Fortaleza · Hospital Araújo Jorge (Site 2514), Goiânia · Liga Norte Riograndense Contra o Cancer (Site 2513), Natal · Hospital de Clínicas de Passo Fundo (Site 2504), Passo Fundo · Hospital Moinhos de Vento (Site 2510), Porto Alegre · Hospital Nossa Senhora Da Conceicao (Site 2512), Porto Alegre · Instituto Nacional de Câncer - INCA (Site 2501), Rio de Janeiro · Instituto de Oncologia Saint Gallen (Site 2507), Santa Cruz do Sul
Registry updated 2026-10-30
NCT07513376
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Hospital de Clínicas de Passo Fundo (Site 3601), Pasos Fundo · Hospital Samaritano De Sao Paulo (Site 3612), São Paulo · Hospital Sírio Libanês (Site 3611), São Paulo
Registry updated 2026-10-30
NCT04928846
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AbbVie
Fundacao Pio XII - Hospital de Cancer de Barretos /ID# 233247, Barretos · Hospital Da Crianca Santo Antonio /ID# 233249, Porto Alegre · Instituto Dor de Pesquisa e Ensino /ID# 233245, Rio de Janeiro · Instituto Nacional de Cancer (INCA) /ID# 231509, Rio de Janeiro · Clinica Amo - Rio Vermelho /ID# 231604, Salvador · Casa de Saúde Santa Marcelina /ID# 231605, São Paulo · OC Oncoclínicas SP /ID# 261828, São Paulo · Instituto de Ensino e Pesquisas Sao Lucas /ID# 247417, São Paulo · Hospital Sirio Libanes - Sao Paulo /ID# 261827, São Paulo
Registry updated 2026-10-29
NCT06422143
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Hospital Nossa Senhora da Conceição (Site 0300), Porto Alegre · Irmandade da Santa Casa de Misericórdia de Porto Alegre (Site 0311), Porto Alegre · Hospital do Cancer de Pernambuco (Site 0312), Recife · Instituto de Oncologia Saint Gallen (Site 0304), Santa Cruz do Sul · Hospital de Base de São José do Rio Preto (Site 0310), São José do Rio Preto · ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO (Site 0302), São Paulo · Hospital Paulistano (Site 0307), São Paulo · Vencer Centro de Pesquisa Clínica (Site 0309), Teresina
Registry updated 2026-10-29
NCT06692738
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AstraZeneca
Barretos · Florianópolis · Ijuí · Londrina · Porto Alegre · Salvador · São Paulo · Taubaté
Registry updated 2026-10-29
NCT06357533
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Trial Treatment · Phase 3 · AstraZeneca
Barretos · Curitiba · Florianópolis · Ipatinga · Natal · Porto Alegre · Rio de Janeiro · Santa Maria · São Paulo · Taubaté
Registry updated 2026-10-28
NCT06627647
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Trial Treatment · Phase 3 · AstraZeneca
Ijuí · Londrina · Passo Fundo · Porto Alegre · Salvador · São Paulo · Taubaté · Vitória
Registry updated 2026-10-28
NCT06996782
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 1/2 · AstraZeneca
Barretos · Fortaleza · Natal · Pelotas · Porto Alegre · São Paulo
Registry updated 2026-10-28

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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