Lung cancer: open trials in Israel

67 open trials have a site in Israel. Registry data; only the trial team decides who can take part.

NCT05789082
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Rambam Medical Center, Haifa · Rabin MC, Petah Tikva · Tel Aviv Sourasky Medical Ctr, Tel Aviv
Registry updated 2026-11-05
NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · Pfizer
Shaare Zedek Medical Center, Jerusalem · Hadassah medical Center, Jerusalem · Rabin Medical Center, Petah Tikva · Sheba medical center, Ramat Gan · Sourasky Medical Center, Tel Aviv · Yitzhak Shamir Medical Center, Tsrifin
Registry updated 2026-11-05
NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 3 · Bayer
Assuta Ashdod Public Hospital (R.A), Ashdod · Clalit Health | Soroka Medical Center - Oncology department, Beersheba · Shaare-Zedek Medical Center, Oncology Institute, Jerusalem · Tel Aviv Sourasky Medical Center - Oncology Department, Tel Aviv
Registry updated 2026-11-04
NCT06890598
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Eli Lilly and Company
Rambam Health Care Campus, Haifa · Shaare Zedek Medical Center, Jerusalem · Meir Medical Center, Kfar Saba · Sheba medical center, Ramat Gan
Registry updated 2026-11-04
NCT05498428
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Trial Treatment · Phase 2 · Janssen Research & Development, LLC
Rambam Medical Center, Haifa · Shaare Zedek Medical Center, Jerusalem · Meir Medical Center, Kfar Saba · Rabin Medical Center, Petah Tikva · Sheba medical center, Ramat Gan
Registry updated 2026-11-03
NCT06667076
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 2 · Janssen Research & Development, LLC
Soroka Medical Center, Beersheba · Rambam Medical Center, Haifa · Meir Medical Center, Kfar Saba · Sheba medical center, Ramat Gan
Registry updated 2026-11-03
NCT07230691
A Study of Clinical Outcomes in Participants With EGFR Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) in a Real-World Setting
Research · Janssen Research & Development, LLC
Rabin Medical Center, Petah Tikva · Sheba medical center, Ramat Gan · Assuta MC, Tel Aviv
Registry updated 2026-11-03
NCT07195695
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Trial Treatment · Phase 3 · Boehringer Ingelheim
Rambam Health Care Campus, Haifa · Shaare Zedek Medical Center, Jerusalem · Meir Medical Center, Kfar Saba · Sheba medical center, Ramat Gan · Sourasky Medical Center, Tel Aviv
Registry updated 2026-11-02
NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Trial Treatment · Phase 2/3 · Mirati Therapeutics Inc.
Emek Medical Center, Afula · Rambam Health Care Campus, Bat Galim · Soroka Medical Center, Beersheba · Local Institution - 007-263, Holon · Hadassah University Hospital - Ein Kerem, Jerusalem · Shaare Zedek Medical Center, Jerusalem · Kaplan Medical Center, Rehovot · Tel-Aviv Sourasky Medical Center, Tel Aviv · Ziv Medical Center, Zsfat
Registry updated 2026-10-30
NCT06623422
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Rambam Health Care Campus (Site 1603), Haifa · Shaare Zedek Medical Center (Site 1601), Jerusalem · Hadassah Medical Center (Site 1605), Jerusalem · Meir Medical Center (Site 1606), Kfar Saba · Sheba Medical Center (Site 1602), Ramat Gan
Registry updated 2026-10-30
NCT07513376
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Rambam Health Care Campus (Site 3303), Haifa · Hadassah Medical Center (Site 3305), Jerusalem · Shaare Zedek Medical Center (Site 3301), Jerusalem · Meir medical center (Site 3306), Kfar Saba · Rabin Medical Center (Site 3304), Petah Tikva · Sheba Medical Center (Site 3302), Ramat Gan
Registry updated 2026-10-30
NCT04165070
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Soroka Medical Center (Site 0072), Beersheba · Rambam Health Care Campus-Oncology (Site 0076), Haifa · Shaare Zedek Medical Center (Site 0075), Jerusalem · Meir Medical Center (Site 0071), Kfar Saba · Rabin Medical Center (Site 0074), Petah Tikva · Chaim Sheba Medical Center (Site 0070), Ramat Gan · Sourasky Medical Center (Site 0077), Tel Aviv
Registry updated 2026-10-29
NCT04165798
KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)
Research · Merck Sharp & Dohme LLC
Soroka Medical Center (Site 0072), Beersheba · Rambam Health Care Campus-Oncology (Site 0076), Haifa · Shaare Zedek Medical Center (Site 0075), Jerusalem · Meir Medical Center (Site 0071), Kfar Saba · Rabin Medical Center (Site 0074), Petah Tikva · Chaim Sheba Medical Center (Site 0070), Ramat Gan · Sourasky Medical Center (Site 0077), Tel Aviv
Registry updated 2026-10-29
NCT04928846
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AbbVie
Soroka University Medical Center /ID# 252711, Beersheba · The Edith Wolfson Medical Center /ID# 233781, Holon · ZIV Medical Center /ID# 238606, Safed · Tel Aviv Sourasky Medical Center /ID# 260519, Tel Aviv
Registry updated 2026-10-29
NCT06422143
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Rambam Health Care Campus-Oncology Division (Site 1302), Haifa · Shaare Zedek Medical Center (Site 1300), Jerusalem · Rabin Medical Center (Site 1303), Petah Tikva · Sheba Medical Center (Site 1301), Ramat Gan
Registry updated 2026-10-29
NCT04886804
Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
Trial Treatment · Phase 1 · Boehringer Ingelheim
Rambam Medical Center, Haifa · Meir Medical Center, Kfar Saba · Sourasky Medical Center, Tel Aviv · The Chaim Sheba Medical Center Tel HaShomer, Tel HaShomer
Registry updated 2026-10-28
NCT06875310
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Trial Treatment · Phase 3 · Mirati Therapeutics Inc.
Carmel Hospital, Haifa · Hadassah medical Center, Jerusalem · Rabin Medical Center, Petah Tikva · Sheba medical center, Ramat Gan · Yitzhak Shamir Medical Center, Tsrifin
Registry updated 2026-10-27
NCT07155174
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Trial Treatment · Phase 2 · AbbVie
Assuta Ashdod Medical Center /ID# 276661, Ashdod · Rambam Health Care Campus- Haifa /ID# 276663, Haifa · Hadassah Medical Center-Hebrew University /ID# 276662, Jerusalem · Meir Medical Center /ID# 277292, Kefar Sava · The Chaim Sheba Medical Center /ID# 276660, Ramat Gan
Registry updated 2026-10-27
NCT07190248
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Yitzhak Shamir Medical Center. (Site 1709), Beer Ya Akov · Shaare Zedek Medical Center (Site 1706), Jerusalem · Meir Medical Center. (Site 1702), Kfar Saba · Sheba Medical Center (Site 1700), Ramat Gan · Sourasky Medical Center (Site 1705), Tel Aviv
Registry updated 2026-10-26
NCT07063745
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Afula · Rambam Health Care Campus, Haifa · Hadassah medical Center, Jerusalem · Jerusalem · Meir Medical Center, Kfar Saba · Sheba medical center, Ramat Gan
Registry updated 2026-10-23
NCT06568939
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 2 · AbbVie
Rambam Health Care Campus- Haifa /ID# 270078, Haifa · Shaare Zedek Medical Center /ID# 270095, Jerusalem · Meir Medical Center /ID# 270071, Kefar Sava · Rabin Medical Center. /ID# 270087, Petah Tikva · The Chaim Sheba Medical Center /ID# 270068, Ramat Gan
Registry updated 2026-10-22
NCT05099172
First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 1/2 · Bayer
Rabin Medical Center-Beilinson Campus, Petah Tikva · Chaim Sheba Medical Center, Ramat Gan
Registry updated 2026-10-21
NCT06801834
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Trial Treatment · Phase 3 · Gilead Sciences
Soroka Medical Center, Beersheba · Rambam Health Care Campus, Haifa · Hadassah medical Center, Jerusalem · Meir Medical Center, Kfar Saba · Galilee Medical Center, Naharyia
Registry updated 2026-10-20
NCT07099898
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]
Trial Treatment · Phase 3 · GlaxoSmithKline
Jerusalem · Tel Aviv
Registry updated 2026-10-20
NCT07227597
A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Rambam Health Care Campus (Site 0602), Haifa · Sheba Medical Center (Site 0601), Ramat Gan
Registry updated 2026-10-20

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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