Lupus (SLE): open trials in Brazil

10 open trials have a site in Brazil. Registry data; only the trial team decides who can take part.

NCT05039619
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Trial Treatment · Phase 2 · Hoffmann-La Roche
Centro de Pesquisa Sao Lucas, Campinas · Hospital Universitário Onofre Lopes - UFRN, Petrópolis · Instituto de Ensino da Saude e Gestao - IESG, Salvado · Ser Servicos Especializados Em Reumatologia, Salvador · Universidade Federal de Sao Paulo - UNIFES, São Paulo · Hospital das Clinicas FMUSP, São Paulo
Registry updated 2026-11-03
NCT07175285
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Research · Bristol-Myers Squibb
Hospital de Clinicas de Porto Alegre, Porto Alegre · Hospital Sao Lucas da PUCRS, Porto Alegre · LMK Servicos Medicos SS, Porto Alegre · São Paulo
Registry updated 2026-11-02
NCT07053800
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
Trial Treatment · Phase 2 · Autolus Limited
Instituto D'Or de Pesquisa e Ensino - Hospital Sao Rafael, Salvador
Registry updated 2026-10-30
NCT07659704
CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus
Trial Treatment · Phase 1/2 · University of Sao Paulo
Hospital das Clinicas de Ribeirão Preto (HCFMRP-USP), Ribeirão Preto · Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP), São Paulo
Registry updated 2026-10-29
NCT07201558
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Trial Treatment · Phase 1 · AstraZeneca
Porto Alegre · Salvador · São Paulo
Registry updated 2026-10-28
NCT07598396
A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
Trial Treatment · Phase 2 · Hoffmann-La Roche
L2IP - Instituto de Pesquisas Clínicas Ltda, Brasília · IPC MT Instituto de Pesquisas Clinicas do Mato Grosso, Cuiab · Complexo Hospitalar de Niteroi, Niterói · LMK Servios Mdicos S/S Ltda, Porto Alegre · Hospital das Clinicas de Ribeirao Preto, Ribeiro Preto · Clnica SER da Bahia, Salvador · Hospital das Clnicas da Faculdade de Medicina da USP, São Paulo
Registry updated 2026-10-19
NCT06711887
Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Belo Horizonte · Recife · Salvador · Santo André · Vitória
Registry updated 2026-10-13
NCT06419205
A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
Trial Treatment · Phase 2 · Akebia Therapeutics
São Paulo
Registry updated 2026-10-01
NCT07115745
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Trial Treatment · Phase 1 · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Porto Alegre · Salvador · São Paulo
Registry updated 2026-07-14
NCT07493655
Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis
Trial Treatment · Federal University of Maranhao
University Hospital of the Federal University of Maranhão, São Luís
Registry updated 2026-03-25

All Lupus (SLE) trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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