Lupus (SLE): open trials in Spain

10 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT05039619
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Trial Treatment · Phase 2 · Hoffmann-La Roche
Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat · Hospital Universitario La Paz, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-03
NCT07175285
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Research · Bristol-Myers Squibb
Hospital Clinic de Barcelona, Barcelona · Hospital de Mérida, Mérida
Registry updated 2026-11-02
NCT06925542
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
Trial Treatment · Phase 1 · CRISPR Therapeutics
Hospital Universitario Reina Sofia, Córdoba · Clinica Universidad de Navarra - Pamplona, Pamplona · Hospital Universitario Virgen del Rocio, Seville · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-10-26
NCT06711887
An open-label extension study to assess the efficacy and safety of ianalumab with or without study treatment withdrawal in adult participants with lupus nephritis who have completed study treatment in the CVAY736K12301 core study (SIRIUS-LN extension)
Trial Treatment · Phase 3 · Novartis Pharma AG
Hospital Universitari Vall d'Hebron, Barcelona · Clínica Universidad de navarra, Pamplona · Complexo Hospitalario Universitario De Vigo, Vigo
Registry updated 2026-09-28
NCT07201129
A research trial to assess if cenerimod is efficacious and safe to treat active lupus nephritis on top of regular treatment
Trial Treatment · Phase 3 · Viatris Innovation GmbH
Accellacare Espana S.L., Alcobendas · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Basurto, Bilbao · Hospital Universitari de Girona Doctor Josep Trueta, Girona · Hospital General Universitario Gregorio Marañón, Madrid · Clínica Universidad de navarra, Pamplona · Hospital Universitario Dr. Peset Aleixandre, Valencia
Registry updated 2026-09-28
NCT06121297
A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Systemic Lupus Erythematosus
Trial Treatment · Phase 1/2 · Cabaletta Bio Inc.
Clinica Universidad de Navarra, Madrid · Clínica Universidad de navarra, Pamplona
Registry updated 2026-09-22
NCT07629583
Clinical Study to Evaluate the Effects of Cevostamab in Patients with Lupus with or without Active Lupus Nephritis
Trial Treatment · Phase 1 · Genentech Inc.
Clínica Universidad de navarra, Pamplona · Hospital Universitario Virgen De La Macarena, Sevilla · Hospital Universitario Araba, Vitoria
Registry updated 2026-07-31
NCT07799116
Phase I-IIa, national, multicenter, clinical trial to evaluate the safety and preliminary efficacy of CAR-T CD19 therapy in patients with refractory lupus nephritis.
Trial Treatment · Phase 1/2 · Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz
Hospital Germans Trias i Pujol, Badalona · Hospital Universitario De Leon, León · Hospital Universitario Fundación Jiménez Díaz, Madrid · University Clinical Hospital Virgen De La Arrixaca, Murcia · Clínica Universidad de navarra, Pamplona · Hospital Universitario De Salamanca, Salamanca · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · University Hospital Virgen Del Rocio S.L., Sevilla
Registry updated 2026-06-11
NCT06975787
Dose Escalation Study with Bispecific Antibodies in Adult Patients with Lupus Nephritis
Trial Treatment · Phase 1 · Regeneron Pharmaceuticals Inc.
Hospital Universitario 12 de Octubre, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Regional de Málaga, Málaga · Clínica Universidad de navarra, Pamplona · University Hospital Virgen Del Rocio S.L., Sevilla
Registry updated 2026-05-04
NCT03673748
“A Phase II, double-blinded, placebo-controlled clinical trial to evaluate the safety and efficacy of mesenchymal cells (MSV-ALLO®) in the treatment of lupus nephritis”
Trial Treatment · Phase 2/3 · Hospital Universitario Rio Hortega
Hospital Universitario Rio Hortega, Valladolid
Registry updated 2024-11-20

All Lupus (SLE) trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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