Mantle cell lymphoma: open trials in Japan

• NCT07101328

  A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

  Trial Treatment · Phase 1 · Eli Lilly and Company

  National Cancer Center Hospital East, Chiba · Okayama University Hospital, Okayama · National Cancer Center Hospital, Tokyo · The Cancer Institute Hospital of JFCR, Tokyo

  Registry updated 2026-11-04

• NCT06742996

  A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

  Trial Treatment · Phase 3 · BeOne Medicines

  Institute of Science Tokyo Hospital, Bunkyoku · Chiba Cancer Center, Chiba · Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, Hiroshima · Kagoshima University Hospital, Kagoshima · Kobe City Medical Center General Hospital, KobeShi · Dokkyo Medical University Saitama Medical Center, Koshigaya · Kurashiki Central Hospital, Kurashikishi · Matsuyama Red Cross Hospital, Matsuyama · Aichi Cancer Center Hospital Clinical Oncology, Nagoya · Ogaki Municipal Hospital, Ōgaki · National Hospital Organization Okayama Medical Center, Okayama · Osaka Metropolitan University Hospital, Osaka · Osaka Red Cross Hospital, Osakashi · Hokkaido University Hospital, Sapporo · Tohoku University Hospital, Sendai · Toyohashi Municipal Hospital, Toyohashishi · Yokohama Municipal Citizens Hospital, Yokohama · Kanagawa Cancer Center, Yokohama

  Registry updated 2026-10-29

• NCT06564038

  A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

  Trial Treatment · Phase 1/2 · AstraZeneca

  Kōtoku · Matsuyama · Nagoya

  Registry updated 2026-10-28

• NCT05006716

  A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

  Trial Treatment · Phase 1/2 · BeOne Medicines

  Chiba Cancer Center, Chiba · National Cancer Center Hospital East, Kashiwa · Cancer Institute Hospital of JFCR, Kōtoku · Aichi Cancer Center Hospital Clinical Oncology, Nagoya · Yokohama Municipal Citizens Hospital, Yokohama

  Registry updated 2026-10-05

• NCT06542250

  A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

  Trial Treatment · Phase 1/2 · AstraZeneca

  Chūōku · Kashiwa

  Registry updated 2026-09-30

All Mantle cell lymphoma trials and the map

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