Melanoma: open trials in Spain

51 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT07519655
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
Trial Treatment · Phase 1 · Pfizer
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Fundación Jiménez Díaz, Madrid
Registry updated 2026-11-05
NCT07492680
A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Trial Treatment · Phase 2 · Bristol-Myers Squibb
Hospital Universitari Vall d'Hebron, Barcelona · Hospitalet · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Virgen del Rocio, Seville
Registry updated 2026-11-04
NCT03340506
Dabrafenib and/or Trametinib Rollover Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario HM Sanchinarro, Madrid · Hospital Universitario Fundación Jiménez Díaz, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-03
NCT06953089
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
Trial Treatment · Phase 2 · DualityBio Inc.
Complexo Hospitalario Universitario A Coruña, A Coruña · Hospital HM Nou Delfos, Barcelona · Institut Català d'Oncologia, Girona · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Fundacion Rioja Salud, Logrono
Registry updated 2026-10-29
NCT07221734
Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma
Trial Treatment · Phase 3 · mAbxience Research S.L.
Barcelona · Bilbao · Huelva · Lleida · Madrid · Madrid · Madrid · Málaga · Sabadell · Seville · Torrejón de Ardoz
Registry updated 2026-10-29
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Universitario 12 de Octubre, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Ramón y Cajal, Madrid · HOSPITAL REGIONAL UNIVERSITARIO de MALAGA AVDA., Málaga · Hospital Universitario Virgen Macarena, Seville · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-10-26
NCT06330064
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Trial Treatment · Phase 1/2 · Daiichi Sankyo
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario La Paz, Madrid · Hospital Clínico San Carlos, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Virgen De La Macarena, Sevilla
Registry updated 2026-10-26
NCT07883954
Development and Multi-Centre Validation of a Novel Non-Invasive Melanoma Molecular Diagnostic Test
Research · Mitra Bio
IDIBAPS, Barcelona
Registry updated 2026-10-21
2025-521919-39-00
A PK study to compare JPB898 (proposed nivolumab biosimilar) and US-licensed Opdivo® in participants with resected stage IIB, IIC, or III melanoma in the adjuvant setting
Trial Treatment · Phase 1 · H e x a l AG
Hospital Universitario de Badajoz, Badajoz · Hospital Universitari Dexeus Grupo Quironsalud, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital San Pedro De Alcántara, Cáceres · Hospital Universitario Clínico San Cecilio, Granada · Hospital Jerez Puerta Del Sur Grupo Hla S.A., Jerez De La Frontera · Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria · Micancer Center S.L.P., Lleida · MD Anderson Cancer Center, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Beata María Ana, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Hospital Universitario Regional de Málaga, Málaga · Hospital Universitario Central De Asturias, Oviedo · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Parc Tauli Hospital Universitari, Sabadell · Hospital Universitario de Canarias, San Cristóbal de La Laguna · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario de Torrejon, Torrejón de Ardoz · Fundación Instituto Valenciano de Oncología, Valencia
Registry updated 2026-10-19
NCT07070232
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Trial Treatment · Phase 1/2 · BioNTech SE
START Barcelona HM Nou Delfos, Barcelona · Hospital Universitari Vall d'Hebron - VHIO, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital de San Pedro, Logroño · Centro Integral Oncologico Clara Campal, Madrid · Hospital Beata María Ana, Madrid · Hospital Universitario Fundación Jiménez Díaz, Madrid · Hospital Clínico San Carlos, Madrid · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitari i Politécnic La Fe, Valencia
Registry updated 2026-10-09
NCT06697301
Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Institut Catala d'Oncologia, Badalona · Hospital Universitari Dexeus Grupo Quironsalud, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital San Pedro De Alcántara, Cáceres · Institut Català d'Oncologia, Girona · Hospital de Jerez de la Frontera, Jerez de la Frontera · Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria · Hospital Universitario Lucus Augusti, Lugo · Hospital Universitario HM Sanchinarro, Madrid · Hospital Universitario 12 de Octubre, Madrid · Instituto Multidisciplinar De Oncologia S.A., Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Regional de Málaga, Málaga · Hospital Universitario Virgen de la Victoria, Málaga · University Clinical Hospital Virgen De La Arrixaca, Murcia · Hospital Universitario Marqués de Valdecilla, Santander · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Fundación Instituto Valenciano de Oncología, Valencia · Instituto De Investigacion Sanitaria Fundacion Para La Investigacion Del Hospital Clinico De Valencia-INCLIVA, Valencia
Registry updated 2026-10-06
2026-526261-14-00
PHOENIX - ECP: Extracorporeal PHotopheresis for immune-related cOlitis and/or hEpatitis in advanced melaNoma with inadequate response to steroId eXposure
Trial Treatment · Phase 2 · Therakos Europe Limited
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario 12 de Octubre, Madrid · University Clinical Hospital Virgen De La Arrixaca, Murcia
Registry updated 2026-10-05
NCT06270706
A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 1 · Pliant Therapeutics, Inc.
Hospital Universitari Quirónsalud (NEXT Barcelona), Barcelona · START Barcelona Hospital HM Nou Delfos, Barcelona · START Center for Cancer Research - La Rioja, Logroño · START Madrid / Hospital Universitario Fundacion Jimenez Diaz, Madrid · University Hospital Quironsalud Madrid (NEXT Madrid), Madrid · START Madrid / Centro Integral Oncologico Clara Campal, Madrid
Registry updated 2026-10-02
NCT06961006
A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Hospital Universitari Vall d Hebron ( Site 3081), Barcelona · Hospital Clínic Barcelona ( Site 3080), Barcelona · Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 3082), Madrid
Registry updated 2026-09-28
NCT07476326
Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma
Trial Treatment · Phase 1 · Biocon Biologics UK PLC
Instituto Oncologico Dr. Rosell S.L., Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Fundación Jiménez Díaz, Madrid · University Clinical Hospital Virgen De La Arrixaca, Murcia · Parc Tauli Hospital Universitari, Sabadell · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Virgen De La Macarena, Sevilla
Registry updated 2026-09-25
NCT05727904
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
Trial Treatment · Phase 3 · Iovance Biotherapeutics, Inc.
Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Dexeus Grupo Quironsalud, Barcelona · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario HM Sanchinarro, Madrid · Hospital Universitario 12 de Octubre, Madrid · Clinica Universidad de Navarra, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Regional de Málaga, Málaga · Clínica Universidad de navarra, Pamplona · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario Marqués de Valdecilla, Santander · Hospital Universitario Virgen De La Macarena, Sevilla · Hospital General Universitario de Valencia, Valencia
Registry updated 2026-09-24
NCT04752826
BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)
Trial Treatment · Phase 1/2 · BioInvent International AB
Institut Catala d Oncologia Hospital Duran i Reynals, Barcelona · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Puerta de Hierro-Majadahonda, Madrid,, Madrid · START Madrid / Hospital Universitario Fundacion Jimenez Diaz, Madrid
Registry updated 2026-09-18
NCT07057596
Neoadjuvant Tebentafusp in Patients With Metastatic Uveal Melanoma
Trial Treatment · Phase 2 · Grupo Español Multidisciplinar de Melanoma
Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario La Paz, Madrid · Hospital General Universitario de Valencia, Valencia
Registry updated 2026-09-15
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Research · Guardant Health, Inc.
Hospital Teresa Herrera (C.H.U.A.C), A Coruña · Hospital Clinic of Barcelona, Barcelona · ICO Institut Catala d'Oncologia, Barcelona · Vall Hebron Institute of Oncology, Barcelona · Instituto Catalan de Oncologia de Girona, Girona · Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria · Hospital San Carlos, Madrid · CIOSS HM Sanchinarro, Madrid · Hospital Universitario La Paz, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · CCS Hospital Universitari Parc Taulí, Sabadell · Hospital Clinico de Santiago de Compostela, Santiago de Compostela · Hospital Clínico de Valencia, Valencia
Registry updated 2026-09-14
NCT04913285
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Trial Treatment · Phase 1 · Pierre Fabre Medicament
Arance, Barcelona · Hospital Quiron Dexeus, Barcelona · Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria · START Madrid, Madrid · NEXT Quirónsalud Madrid, Madrid · Hospital General Gregorio Marañón, Madrid · H. Regional de Málaga, Málaga · H. Virgen Macarena, Seville · INCLIVA (Hospital Clinico de Valencia), Valencia · Berrocal, Valencia
Registry updated 2026-09-02
NCT07475572
Pharmacokinetic Similarity Study to Compare AVT32-DRL_PB With Keytruda® in Participants With Fully Resected Melanoma
Trial Treatment · Phase 1 · Alvotech Swiss AG
Institut Catala d'Oncologia, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital San Pedro De Alcántara, Cáceres · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital Quironsalud Malaga, Málaga · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario Virgen De La Macarena, Sevilla
Registry updated 2026-08-24
NCT07338968
A Long-Term Follow-Up Study of Subjects Completing the AU-011-301(CoMpass) for Early Choroidal Melanoma
Research · Phase 3 · Aura Biosciences
Bellvitge University Hospital, L'hospitalet De Llobregat · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Hospital Universitario Virgen De La Macarena, Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-08-19
NCT04895709
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Bristol-Myers Squibb
Institut Catalan d Oncologia (ICO) - Badalona, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Fundación Jiménez Díaz-START Madrid-FJD, Madrid · Hospital Universitario 12 de Octubre, Madrid · Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid-CIOCC, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Clinica Universidad de Navarra-oNCOLOGY, Pamplona
Registry updated 2026-08-17
NCT05592626
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Marengo Therapeutics, Inc.
Vall d'Hebron Institute of Oncology, Barcelona · Hospital Universitario Quirónsalud Madrid, Madrid · START Madrid-FJD, Madrid · Instituto de Investigacion Sanitaria, INCLIVA, Valencia
Registry updated 2026-08-11
NCT04855435
Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours
Trial Treatment · Phase 1 · MonTa Biosciences ApS
Institut Catalá de Oncologia - Hospital Duran i Reynals., Barcelona · Centro Integral Oncológico Clara Campal (CIOCC), Madrid · Fundacion Instituto de Investigacion Sanitaria Fundacion Jimenez Diaz (FJD), Madrid · Consorcio Hospital General Universitario de Valencia, Valencia
Registry updated 2026-08-10

All Melanoma trials and the map

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