Melanoma: open trials in Greece

• NCT07221734

  Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma

  Trial Treatment · Phase 3 · mAbxience Research S.L.

  Efkarpia

  Registry updated 2026-10-29

• 2025-521919-39-00

  A PK study to compare JPB898 (proposed nivolumab biosimilar) and US-licensed Opdivo® in participants with resected stage IIB, IIC, or III melanoma in the adjuvant setting

  Trial Treatment · Phase 1 · H e x a l AG

  St. Luke's Hospital S.A., Thessaloniki · Theageneio Cancer Hospital, Thessaloniki · Athens Medical Center S.A., Thessaloniki

  Registry updated 2026-10-19

• NCT06961006

  A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

  Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC

  General Hospital of Athens "Laiko" ( Site 2080), Athens · Metropolitan Hospital ( Site 2082), Athens · European Interbalkan Medical Center ( Site 2081), Thessaloniki

  Registry updated 2026-09-28

• NCT05727904

  Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

  Trial Treatment · Phase 3 · Iovance Biotherapeutics, Inc.

  Laiko General Hospital of Athens, Athens · General University Hospital Of Patras, Patras

  Registry updated 2026-09-24

• NCT06264180

  VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

  Trial Treatment · Phase 3 · Replimune, Inc.

  Laiko General Hospital of Athens, Athens · General Hospital Of Thessaloniki Papageorgiou, Efkarpia

  Registry updated 2026-07-15

• 2025-521562-95-00

  Randomised, Multicentre, Multinational, Double-Blind Integrated Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 (Proposed Nivolumab Biosimilar) Versus EU-/US-Opdivo in Subjects With Previously Untreated Advanced (Unresectable or Metastatic) Melanoma (LEON Study)

  Trial Treatment · Phase 3 · Mabxience Research S.L.

  Metropolitan General Hospital Healthcare Facilities Operation And Management Single Member S.A., Cholargos · General Hospital Of Thessaloniki Papageorgiou, Efkarpia

  Registry updated 2026-06-04

• NCT07015190

  Neoadjuvant Darovasertib in Primary Uveal Melanoma

  Trial Treatment · Phase 3 · IDEAYA Biosciences

  PAGNI-University General Hospital of Heraklion, Heraklion · University General Hospital of Larissa, Larissa · AHEPA University General Hospital of Thessaloniki, Thessaloniki

  Registry updated 2026-05-06

• NCT06887348

  A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

  Research · Phase 4 · Replimune, Inc.

  Andreas Syngros Hospital Of Venereal And Dermatological Diseases, Athens · Hippokration Hospital, Athens · Laiko General Hospital of Athens, Athens

  Registry updated 2026-01-12

All Melanoma trials and the map

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