Multiple sclerosis: open trials in Brazil

5 open trials have a site in Brazil. Registry data; only the trial team decides who can take part.

NCT06846281
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Novartis Investigative Site, Fortaleza · Novartis Investigative Site, Joinville · Novartis Investigative Site, Porto Alegre · Novartis Investigative Site, São Paulo
Registry updated 2026-10-26
NCT07161258
A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)
Trial Treatment · Phase 2 · Hoffmann-La Roche
L2IP - Instituto de Pesquisas Clínicas Ltda, Brasília · Instituto de Neurologia de Curitiba - Hospital Ecoville, Curitiba · Nucleo de Pesquisa Clinica do Rio Grande do Sul NPCR, Porto Alegre · Centro de Pesquisas Clinicas - CPCLIN, São Paulo
Registry updated 2026-10-13
NCT07225504
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Novartis Investigative Site, Fortaleza · Novartis Investigative Site, Joinville · Novartis Investigative Site, Porto Alegre · Novartis Investigative Site, Rio de Janeiro · Novartis Investigative Site, Santo André · Novartis Investigative Site, São Paulo
Registry updated 2026-10-13
NCT07325292
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
Trial Treatment · Phase 3 · Sanofi
L2IP - Instituto de Pesquisas Clínicas- Site Number : 0760003, Brasília · Instituto de Neurologia de Curitiba - Ecoville- Site Number : 0760001, Curitiba · Clínica Neurológica- Site Number : 0760007, Joinville
Registry updated 2026-10-13
NCT07282574
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)
Trial Treatment · Phase 2 · Hoffmann-La Roche
Centro de Pesquisas Clinicas - CPCLIN, São Paulo
Registry updated 2026-10-07

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Multiple sclerosis: open trials in Brazil

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)