Multiple sclerosis: open trials in Portugal

17 open trials have a site in Portugal. Registry data; only the trial team decides who can take part.

NCT07067463
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Trial Treatment · Phase 3 · Zenas BioPharma (USA), LLC
Unidade Local De Saude De Santa Maria E.P.E., Lisbon · Unidade Local De Saude De Santo Antonio E.P.E., Porto · Unidade Local De Saude De Entre O Douro E Vouga E.P.E., Santa Maria Da Feira · Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora
Registry updated 2026-11-03
2023-504358-36-00
Efficacy and safety study of frexalimab (SAR441344) in adults with relapsing forms of multiple sclerosis
Trial Treatment · Phase 3 · Sanofi-Aventis Recherche & Developpement
CCAB Centro Clinico Academico Braga Associacao, Braga · Hospital da Senhora da Oliveira Guimarães, E.P.E., Guimarães · Hospital Pedro Hispano, Matosinhos
Registry updated 2026-10-28
NCT07299019
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Trial Treatment · Phase 3 · Zenas BioPharma (USA), LLC
Unidade Local De Saude De Sao Jose E.P.E., Lisbon · Unidade Local De Saude De Santa Maria E.P.E., Lisbon · Unidade Local De Saude De Santo Antonio E.P.E., Porto · Unidade Local De Saude De Entre O Douro E Vouga E.P.E., Santa Maria Da Feira · Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora
Registry updated 2026-10-27
NCT06846281
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
CCAB Centro Clinico Academico Braga Associacao, Braga · Unidade Local de Saúde de Coimbra, E.P.E., Coimbra · Unidade Local De Saude De Sao Jose E.P.E., Lisbon
Registry updated 2026-10-26
NCT07161258
A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)
Trial Treatment · Phase 2 · Hoffmann-La Roche
Centro Clnico Acadmico - Braga, Associao (2CA-Braga), Braga · Unidade Local de Saúde de Coimbra, E.P.E., Coimbra
Registry updated 2026-10-13
NCT07225504
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Novartis Investigative Site, Braga · Novartis Investigative Site, Lisbon · Novartis Investigative Site, Porto
Registry updated 2026-10-13
NCT07325292
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
Trial Treatment · Phase 3 · Sanofi
CCAB Centro Clinico Academico Braga Associacao, Braga · Unidade Local de Saúde de Coimbra, E.P.E., Coimbra · Unidade Local De Saude Do Alto Ave E.P.E., Guimaraes · Unidade Local De Saude De Sao Jose E.P.E., Lisbon · Hospital da Luz, S.A, Lisbon · Unidade Local De Saude De Lisboa Ocidental E.P.E., Lisbon · Unidade Local De Saude De Matosinhos E.P.E., Matosinhos
Registry updated 2026-10-13
NCT07282574
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)
Trial Treatment · Phase 2 · Hoffmann-La Roche
CCAB Centro Clinico Academico Braga Associacao, Braga · Unidade Local de Saúde de Coimbra, E.P.E., Coimbra · Unidade Local De Saude De Lisboa Ocidental E.P.E., Lisbon · Unidade Local De Saude De Sao Jose E.P.E., Lisbon · Unidade Local De Saude De Entre O Douro E Vouga E.P.E., Santa Maria Da Feira
Registry updated 2026-10-07
2024-511686-11-00
Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis
Trial Treatment · Phase 3 · Novartis Pharma AG
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra · Unidade Local De Saude De Sao Jose E.P.E., Lisbon
Registry updated 2026-09-29
NCT06408259
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Trial Treatment · Phase 3 · Bristol-Myers Squibb
CCAB Centro Clinico Academico Braga Associacao, Braga · Unidade Local de Saúde de Coimbra, E.P.E., Coimbra · Unidade Local De Saude De Sao Jose E.P.E., Lisbon · Unidade Local de Saude de Sao Joao E.P.E., Porto
Registry updated 2026-09-10
2025-521546-23-00
A clinical trial to find out how well LOU064 (remibrutinib) works and how safe it is for people with secondary progressive multiple sclerosis
Trial Treatment · Phase 3 · Novartis Pharma AG
CCAB Centro Clinico Academico Braga Associacao, Braga · Unidade Local De Saude De Lisboa Ocidental E.P.E., Lisbon · Unidade Local De Saude De Santa Maria E.P.E., Lisbon · Unidade Local De Saude De Sao Jose E.P.E., Lisbon · Unidade Local de Saude de Sao Joao E.P.E., Porto
Registry updated 2026-07-30
NCT07734675
Sociocognitive Intervention and Rehabilitation Program in Multiple Sclerosis
Trial Treatment · Sonia Batista
Unidade Local de Saude de Coimbra, Coimbra · Local Health Unit of Coimbra, Coimbra
Registry updated 2026-07-29
NCT05809986
Ofatumumab in Portuguese Multiple Sclerosis Patients - an Observational Study
Research · Novartis Pharmaceuticals
Novartis Investigative Site, Amadora · Novartis Investigative Site, Guimarães · Novartis Investigative Site, Leiria · Novartis Investigative Site, Lisbon · Novartis Investigative Site, Matosinhos Municipality · Novartis Investigative Site, Ponte de Lima · Novartis Investigative Site, Porto · Novartis Investigative Site, Setúbal
Registry updated 2026-07-07
NCT06782724
Psilocybin Therapy for Psychological Distress in Palliative Patients
Trial Treatment · Phase 2 · University Medical Center Groningen
Champalimaud Clinical Centre, Lisbon
Registry updated 2026-05-08
2024-520287-34-01
A phase II randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of an oral solution of 9-Δ tetrahydrocannabinol/cannabidiol (THC/CBD) in multiple sclerosis patients with chronic neuropathic pain
Trial Treatment · Phase 2 · Ferraz Lynce Especialidades Farmaceuticas S.A.
CCAB Centro Clinico Academico Braga Associacao, Braga
Registry updated 2026-02-23
NCT06592352
MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis
Trial Treatment · Phase 2 · Clinical Academic Center (2CA-Braga)
CCAB Centro Clinico Academico Braga Associacao, Braga
Registry updated 2025-08-13
NCT06723444
Improving Learning and Memory in Portuguese Patients With Multiple Sclerosis
Trial Treatment · Centro Hospitalar De São João, E.P.E.
Centro Hospitalar Universitário de São João, Porto
Registry updated 2025-02-12

All Multiple sclerosis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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