Myasthenia gravis: open trials in Italy

32 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT07463521
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis
Trial Treatment · Phase 3 · UCB Biopharma SRL
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Azienda Ospedaliero-Universitaria Careggi, Florence · Azienda Ospedaliera Universitaria Gaetano Martino Messina, Messina · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-11-06
NCT07465289
A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis
Trial Treatment · Phase 3 · UCB Biopharma SRL
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Azienda Ospedaliero-Universitaria Careggi, Florence · Azienda Ospedaliera Universitaria Gaetano Martino Messina, Messina · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Azienda Ospedaliero Universitaria Pisana, Pisa
Registry updated 2026-11-06
NCT04951622
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Neurological Institute Foundation Casimiro Mondino, Pavia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-11-05
NCT06055959
A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
Trial Treatment · Phase 2/3 · UCB Biopharma SRL
IRCCS Foundation Istituto Neurologico Carlo Besta, Milan
Registry updated 2026-11-05
NCT07323316
Holistic Assessment and Remote Digital MONitoring of mYasthenia Gravis Via MyoSense 360
Trial Treatment · Ad scientiam
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan · IRCCS Fondazione Istituto Neurologico Nazionale C. Mondino, Pavia · Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma
Registry updated 2026-11-05
NCT07673627
ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis
Trial Treatment · Phase 2 · argenx
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples · Azienda Ospedaliero-Universitaria Sant Andre, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-11-04
NCT05374590
Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis
Trial Treatment · Phase 2/3 · argenx
Azienda Ospedaliera Universitaria Meyer IRCCS, Florence · IRCCS Istituto Giannina Gaslini, Genoa
Registry updated 2026-11-03
NCT07217587
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples · Azienda Ospedaliero Universitaria Pisana, Pisa · Azienda Ospedaliero-Universitaria Sant Andre, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-11-03
NCT07647510
A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE)
Trial Treatment · Phase 3 · Dianthus Therapeutics
Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-10-30
NCT07294170
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Research · argenx
ASST Papa Giovanni XXIII - Ospedale Papa Giovanni XXIII, Bergamo · Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan · Aorn Antonio Cardarelli, Naples
Registry updated 2026-10-26
NCT06987539
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG)
Trial Treatment · Phase 2 · Amgen
Azienda Ospedaliera Universitaria Meyer IRCCS, Florence · Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-10-23
NCT06463587
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Trial Treatment · Phase 3 · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Instituto Di Ricovero E Cura A Carattere Scientifico, Bologna · IRCCS Ospedale Policlinico San Martino, Genoa · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Azienda Unita' Locale Socio Sanitaria N. 2 Marca Trevigiana, Treviso
Registry updated 2026-10-21
NCT06435312
An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
Trial Treatment · Phase 3 · UCB Biopharma SRL
IRCCS Foundation Istituto Neurologico Carlo Besta, Milan
Registry updated 2026-10-02
2025-522821-37-00
Basket trial for B-cEll driven severe auToimmunE and aLoimmune diseases (chronic Graft vErsUs host diseaSe) treated with anti-CD19 CAR T-cell thErapy
Trial Treatment · Phase 1 · Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-09-29
NCT06392386
A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
Trial Treatment · Phase 2/3 · argenx
IRCCS Istituto Giannina Gaslini, Genoa
Registry updated 2026-09-28
NCT07284420
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
Trial Treatment · Phase 2 · argenx
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples · Azienda Ospedaliero-Universitaria Sant Andre, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-09-24
NCT06414954
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
Trial Treatment · Phase 2 · NMD Pharma A/S
ASST Papa Giovanni XXIII - Azienda Ospedaliera Papa Giovanni XXIII, Bergamo · IRCCS Istituo delle Scienze neurologiche di Bologna, UOC Clinica neurologica Ospedale, Bologna · IRCCS Ospedale Policlinico San Martino, Genova · IRCCS Fondazione Istituto Neurologico Carlo Besta, Dipartimento di Ricerca e Sviluppo clinico, Milan · DIMER, IRCCS, Ospedale San Raffaele, Milan · Centro Sclerosi Multipla Napoli - AOU Vanvitelli, Naples · AOU Pisana, Pisa · Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza, Roma
Registry updated 2026-08-21
NCT07039916
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Trial Treatment · Phase 3 · Immunovant Sciences GmbH
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Azienda Unita Sanitaria Locale Di Bologna, Bologna · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliero-Universitaria di Sassari, Sassari
Registry updated 2026-07-30
NCT07717281
PANORAMA: Neuromuscular Organoids for Refractory AChR+ Myasthenia Gravis
Research · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan
Registry updated 2026-07-21
NCT07595653
A Study to Evaluate the Impact of Efgartigimod on Overall Disease Experience of People Suffering From Generalized Myasthenia Gravis (gMG) in Italy
Research · argenx
Ospedale Generale Regionale " F.Miulli ", Acquaviva delle Fonti · Azienda Ospedaliero-Universitaria delle Marche, Ancona · A.O.U. Consorziale Policlinico, Bari · Asst Papa Giovanni XXIII, Bergamo · Ospedale Bellaria, Bologna · A.O.U. Renato Dulbecco, Catanzaro · A.O.U Careggi, Florence · IRCCS Ospedale Policlinico San Martino, Genova · A.O.U. Policlinico G. Martino, Messina · Ospedale San Raffaele, Milan · IRCCS Istituto Neurologico Carlo Besta, Milan · ASST GOM Niguarda, Milan · IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · A.O.U. Policlinico Universitario, Monserrato · A.O.U. Università della Campania L. Vanvitelli, Naples · AORN A. Cardarelli, Naples · A.O.U. San Luigi Gonzaga, Orbassano · Azienda Ospedale Universita Padova, Padova · IRCCS Fondazione Mondino, Pavia · Azienda Ospedaliera Perugia, Perugia · A.O.U. Pisana, Pisa · Ospedale degli Infermi, Rimini · Ospedale Sant'Andrea, Roma · Fondazione PTV - POLICLINICO TOR VERGATA, Roma · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma · A.O.U. San Giovanni di Dio e Ruggì D'Aragona, Salerno · IRCCS Fondazione Casa Sollievo della Sofferenza, San Giovanni Rotondo · A.O.U. Sassari, Sassari · Ospedale Ca' Foncello, Treviso · AOUI Verona - Policlinico "G.B. Rossi", Verona
Registry updated 2026-05-19
NCT07571525
Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia Gravis
Research · IRCCS San Raffaele
IRCCS Ospedale San Raffaele, Milan
Registry updated 2026-05-06
NCT06312644
Study of Ultomiris® (Ravulizumab) Safety in Pregnancy
Research · Alexion Pharmaceuticals, Inc.
Rome
Registry updated 2026-04-16
NCT07221838
A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab
Trial Treatment · Phase 4 · Alexion Pharmaceuticals, Inc.
Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · Azienda Ospedaliero-Universitaria Sant Andre, Rome
Registry updated 2026-04-09
2023-507539-40-00
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients with Myasthenia Gravis
Trial Treatment · Phase 2 · NMD Pharma A/S
Azienda Ospedaliera Papa Giovanni XXIII, Bergamo · Instituto Di Ricovero E Cura A Carattere Scientifico, Bologna · IRCCS Ospedale Policlinico San Martino, Genoa · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Ospedale San Raffaele S.r.l., Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliero Universitaria Pisana, Pisa · Azienda Ospedaliero-Universitaria Sant Andre, Rome
Registry updated 2026-02-26
NCT04202341
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
Research · Alexion Pharmaceuticals, Inc.
Milan · Naples
Registry updated 2026-02-18

All Myasthenia gravis trials and the map

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