Myasthenia gravis: open trials in United States

• NCT07463521

  A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

  Trial Treatment · Phase 3 · UCB Biopharma SRL

  Mg0038 10106, Amherst · Mg0038 10102, Cincinnati · Mg0038 10103, Columbus · Mg0038 10108, Greenfield · Mg0038 10105, O'Fallon · Mg0038 10104, Scottsdale

  Registry updated 2026-11-06

• NCT07465289

  A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

  Trial Treatment · Phase 3 · UCB Biopharma SRL

  Mg0039 10103, Columbus · Mg0039 10104, Scottsdale

  Registry updated 2026-11-06

• NCT04951622

  A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

  Trial Treatment · Phase 3 · Janssen Research & Development, LLC

  Augusta University, Augusta · University of Colorado Anschutz Medical Campus, Aurora · FM Clinical Research, LLC South Florida Neurology Associates, P. A., Boca Raton · St. Elizabeth Medical Center, Boston · University of Vermont, Burlington · Lahey Hospital & Medical Center, Burlington · Medical University of South Carolina, Charleston · University of Cincinnati, Cincinnati · Cleveland Clinic, Cleveland · The Ohio State University, Columbus · Wesley Neurology, Cordova · UT Southwestern Medical Center, Dallas · Duke University School of Medicine, Durham · University of Florida Health Jacksonville, Jacksonville · University of Kansas Medical Center, Kansas City · University of Southern California, Los Angeles · Yale New Haven Hospital, New Haven · Stanford University, Palo Alto · Neuromuscular Research Center and Clinic, Paradise Valley · Care Access Research, Pasadena · Medsol Clinical Research Center Inc, Port Charlotte · HonorHealth Neurology, Scottsdale · Washington University School of Medicine, St Louis · University of South Florida, Tampa

  Registry updated 2026-11-05

• NCT06055959

  A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis

  Trial Treatment · Phase 2/3 · UCB Biopharma SRL

  Mg0014 50168, Chicago · Mg0014 50574, Denton

  Registry updated 2026-11-05

• NCT05265273

  A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

  Trial Treatment · Phase 2/3 · Janssen Research & Development, LLC

  C S Mott Children's Hospital, Ann Arbor · Children's Hospital Colorado, Aurora · Penn State Milton S Hershey Medical Ctr, Hershey · University of Kansas Medical Center, Lawrence · Childrens Hospital Los Angeles, Los Angeles · Lucile Packard Children's Hospital - Stanford, Palo Alto · Childrens Hospital of Philadelphia, Philadelphia · Phoenix Children s Hospital, Phoenix · University of Pittsburgh Medical Center, Pittsburgh · UCSF Benioff Children's Hospital, San Francisco · University of South Florida Morsani Center for Advanced Healthcare, Tampa

  Registry updated 2026-11-04

• NCT07673627

  ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

  Trial Treatment · Phase 2 · argenx

  Dent Neurologic Institute - Amherst, Amherst · National Neuromuscular Research Institute, Austin · Neurology Center of Southern California, Carlsbad · Erlanger Health System, Chattanooga · Profound Research LLC at Las Vegas Neurology Center, Las Vegas · Visionary Investigators Network, Miami

  Registry updated 2026-11-04

• NCT05374590

  Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis

  Trial Treatment · Phase 2/3 · argenx

  Atrium Health Neurology Specialty Care, Charlotte · University of Virginia (UVA) Health - Developmental Pediatrics Clinic, Charlottesville · Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital, Chicago

  Registry updated 2026-11-03

• NCT07217587

  Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis

  Trial Treatment · Phase 3 · Janssen Research & Development, LLC

  Austin Neuromuscular Center, Austin · SFM Clinical Research LLC, Boca Raton · Research of the Rockies LLC, Colorado Springs · Neurology Clinic, PC, Cordova · Texas Neurology, Dallas · Henry Ford Hospital, Detroit · Michigan State University, East Lansing · University of Connecticut, Farmington · Advanced Neurology of Colorado, Fort Collins · Neurology Center of New England, PC, Foxborough · Neurology Center of North Orange County, Fullerton · The University of Texas Health Science Center at Houston, Houston · Josephson Wallack Munshower Neurology, PC, Indianapolis · EvergreenHealth Neurology, Kirkland · Tulane Center for Clinical Research, New Orleans · Equity Medical, New York · HSHS St. Elizabeth's Hospital, O'Fallon · The Neurology Group, Pomona · Velocity Clinical Research, Inc., Raleigh · Atrium Health Wake Forest Baptist, Winston-Salem

  Registry updated 2026-11-03

• NCT07647510

  A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE)

  Trial Treatment · Phase 3 · Dianthus Therapeutics

  Boca Raton · Fayetteville · Houston · Pasadena

  Registry updated 2026-10-30

• NCT07673744

  A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

  Trial Treatment · Phase 2 · TG Therapeutics, Inc.

  Clearwater · Colorado Springs · Farmington Hills · Greenville · Maitland · New Bern

  Registry updated 2026-10-29

• NCT01793168

  Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

  Research · Sanford Health

  Sanford Health, Sioux Falls

  Registry updated 2026-10-28

• NCT06680037

  A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

  Trial Treatment · Phase 1 · TG Therapeutics, Inc.

  Ann Arbor · Cleveland · Columbus · La Jolla · Milwaukee · New York · Omaha · Rochester

  Registry updated 2026-10-27

• NCT07294170

  ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

  Research · argenx

  Dent Neurologic Institute - Amherst, Amherst · National Neuromuscular Research Institute, Austin · Massachusetts General Hospital, Boston · Profound Research LLC - Carlsbad, Carlsbad · University of North Carolina at Chapel Hill-170 Manning Dr., Chapel Hill · Erlanger Health System, Chattanooga · University of Cincinnati Medical Center - Goodman St, Cincinnati · Ohio State Martha Morehouse Outpatient Care, Columbus · Henry Ford Health System, Detroit · Duke Early Phase Clinical Research Unit - PPDS, Durham · Profound Research LLC at Las Vegas Neurology Center, Las Vegas · Visionary Investigators Network, Miami · University of Texas- San Antonio - Health Science Center - PPDS, San Antonio · University of South Florida, Tampa

  Registry updated 2026-10-26

• NCT06987539

  A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG)

  Trial Treatment · Phase 2 · Amgen

  Austin Neuromuscular Center, Austin · Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago · The Childrens Hospital of Philadelphia, Philadelphia · Seattle Childrens Hospital, Seattle

  Registry updated 2026-10-23

• NCT06626919

  Study of Anitocabtagene Autoleucel in Participants With Non-Oncology Plasma Cell-Related Diseases

  Trial Treatment · Phase 1 · Kite, A Gilead Company

  The Ohio State University -Wexner Medical Center, Columbus · UT Southwestern Medical Center, Dallas · Karmanos Cancer Institute, Detroit · Houston Methodist Hospital, Houston · Ronald Reagan UCLA Medical Center, Los Angeles · University of Minnesota Delaware Clinical Research Unit, Minneapolis · Columbia University Irving Medical Center, New York · UC Irvine Medical Center, Orange · Stanford Blood and Marrow Transplant, Palo Alto · Lewis Katz School of Medicine at Temple University, Philadelphia · Oregon Health Science University, Portland · Mayo Clinic, Rochester · Moffitt Cancer Center, Tampa · University of South Florida - Carol and Frank Morsani Center for Advanced Healthcare, Tampa

  Registry updated 2026-10-22

• NCT06463587

  Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

  Trial Treatment · Phase 3 · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

  Neurology of Central Florida Research Center LLC, Altamonte Springs · SFM Clinical Research LLC, Boca Raton · The University of Vermont Medical Center, Burlington · Miami Valley Hospital South, Centerville · UNC Hospitals - PARENT, Chapel Hill · Clinical Trials of South Carolina - Charleston, Charleston · Erlanger Health, Inc. - 1123255, Chattanooga · University of Cincinnati, Cincinnati · Baylor Scott & White Research Institute - Baylor Scott & White Research Institute, Dallas · ANESC Research, El Paso · Integrated Neurology Services - Dr. Simon Fishman's Office, Falls Church · University of Connecticut Health Center - Department of Medicine, Farmington · BCN Research, Greenfield · University of Florida Health Science Center - 300120311, Jacksonville · University of Kansas Medical Center Research Institute, Inc. - 3901 Rainbow (MAIN), Kansas City · Advanced Neurosciences Research LLC, Longmont · Neurology Associates, P. A., Maitland · Baylor Scott & White Neurology - McKinney, McKinney · Arizona Neuroscience Research, LLC, Phoenix · University of South Florida - PARENT - PARENT, Tampa · The George Washington University Medical Faculty Associates Foggy Bottom South Pavilion, Washington D.C. · Atrium Health Wake Forest Baptist, Winston-Salem

  Registry updated 2026-10-21

• NCT06359041

  RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis

  Trial Treatment · Phase 1/2 · Cabaletta Bio

  University of Colorado, Aurora · Beth Israel Deaconess Medical Center, Boston · Northwestern Memorial Hospital, Chicago · Baylor College of Medicine Neurology Department, Houston · University of Texas - MD Anderson Cancer Center, Houston · Houston Methodist Hospital, Houston · Mayo Clinic Florida, Jacksonville · University of Kansas Medical Center, Kansas City · Columbia University, New York · University of California Irvine, Orange · Oregon Health Science University, Portland · Mayo Clinic - Rochester, Rochester · University of Rochester Medical Center, Rochester · UC Davis, Department of Neurology, Sacramento · University of California San Francisco, San Francisco · Swedish Neuroscience Research, Seattle · University of Massachusetts Chan Medical School, Worcester

  Registry updated 2026-10-19

• NCT07304154

  Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment

  Trial Treatment · Phase 1 · Kite, A Gilead Company

  Hoag Memorial Hospital Presbyterian, Newport Beach · Columbia University Irving Medical Center, New York · Stanford Neuroscience Health Center, Palo Alto · LDS Hospital - Intermountain Health, Salt Lake City · Fred Hutchinson Cancer Center, Seattle

  Registry updated 2026-10-19

• NCT07226830

  Quantification of Change in MG Disease Activity in Individuals With Generalized Myasthenia Gravis (gMG) After Administration of VYVGART® or VYVGART Hytrulo® Using BioDigit MG

  Research · BioSensics

  Massachusetts General Hospital, Neuromuscular Diagnostic Center, Boston

  Registry updated 2026-10-13

• NCT07787247

  Feasibility of Remote Monitoring of Patients With Myasthenia Gravis

  Research · George Washington University

  The George Washington University, Washington D.C.

  Registry updated 2026-10-05

• NCT06392386

  A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

  Trial Treatment · Phase 2/3 · argenx

  Carolinas HealthCare System Neurosciences Institute - Neurology, Charlotte · University of Virginia, Charlottesville · Neurology Rare Disease Center, Denton

  Registry updated 2026-09-28

• NCT07284420

  ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

  Trial Treatment · Phase 2 · argenx

  Dent Neurologic Institute - Amherst, Amherst · National Neuromuscular Research Institute, Austin · Massachusetts General Hospital, Boston · Profound Research LLC - Carlsbad, Carlsbad · University of North Caroline at Chapel Hill-170 Manning Dr, Chapel Hill · Erlanger Health System, Chattanooga · University of Cincinnati Medical Center - Goodman St, Cincinnati · Ohio State Martha Morehouse Outpatient Care, Columbus · Henry Ford Health Systems, Detroit · Duke Early Phase Clinical Research Unit - PPDS, Durham · Profound Research LLC at Las Vegas Neurology Center, Las Vegas · Visionary Investigators Network, Miami · University of Texas- San Antonio - Health Science Center - PPDS, San Antonio · University of South Florida, Tampa

  Registry updated 2026-09-24

• NCT07215949

  Zilucoplan for Severe gMG Exacerbations

  Trial Treatment · Phase 3 · Miriam Freimer

  The Ohio State University, Columbus · University of Kansas Medical Center, Kansas City · University of South Florida (Tampa General Hospital), Tampa

  Registry updated 2026-08-28

• NCT07217509

  PPDTM CorEvitasTM Myasthenia Gravis (MG) Drug Safety and Effectiveness Registry

  Research · CorEvitas

  CorEvitas, LLC, Waltham

  Registry updated 2026-08-27

• NCT06414954

  Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

  Trial Treatment · Phase 2 · NMD Pharma A/S

  Augusta University-Neuroscience Center, Augusta · University of Colorado Neuromuscular Division, Aurora · SFM Clinical Research LLC, Boca Raton · Profound Research LLC, Carlsbad · The University of North Carolina at Chapel Hill, Chapel Hill · NextGen Precision Health, Columbia · The Ohio State University, Columbus · University of California, Irvine Medical Center, Irvine · Semmes Murphey Clinic, Memphis · University of Oregon, Portland · Neuromuscular Research Division | University of South Florida, Tampa

  Registry updated 2026-08-21

All Myasthenia gravis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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