Neuroblastoma: open trials in United Kingdom

• NCT07549321

  A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

  Trial Treatment · Phase 2/3 · Renaissance Pharma Ltd.

  Royal Victoria Infirmary, Newcastle upon Tyne · Southampton Children's Hospital, Southampton · Royal Marsden NHS Foundation Trust, Sutton

  Registry updated 2026-11-03

• NCT06395103

  Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

  Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC

  Birmingham Children's Hospital-Oncology/Haematology (Site 1349), Birmingham · University Hospital of Wales (Site 1346), Cardiff · University College London Hospital (Site 1350), London · Royal Victoria Infirmary-Great North Children's Hospital (Site 1348), Newcastle upon Tyne · Royal Marsden Hospital (Sutton)-Drug Development Unit (Site 1347), Sutton

  Registry updated 2026-10-30

• NCT07334301

  A Multi-Arm, Platform Trial For Relapsed Neuroblastoma

  Trial Treatment · Phase 1/2 · University of Birmingham

  Royal Aberdeen Children's Hospital, Aberdeen · Royal Belfast Hospital for Sick Children, Belfast · Birmingham Children's Hospital, Birmingham · Bristol Royal Hospital for Children, Bristol · Addenbrookes Hospital, Cambridge · Children's Hospital for Wales, Cardiff · Royal Hospital for Sick Children, Edinburgh · Royal Hospital for Children, Glasgow · Leeds General Infirmary, Leeds · Alder Hey Hospital, Liverpool · University College London Hospital, London · Great Ormond Street Hospital, London · Royal Manchester Children's Hospital, Manchester · Royal Victoria Infirmary, Newcastle upon Tyne · Nottingham Children's Hospital, Nottingham · John Radcliffe Hospital, Oxford · Sheffield Children's Hospital, Sheffield · Southampton General Hospital, Southampton · Royal Marsden Hospital, Sutton

  Registry updated 2026-01-12

• NCT05770037

  DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

  Trial Treatment · Phase 2/3 · Cancer Research UK

  Belfast City Hospital, Belfast · Birmingham Children's Hospital, Birmingham · University Hospital Birmingham, Birmingham · Bristol Royal Hospital for Children, Bristol · Bristol Haematology and Oncology Centre, Bristol · Addenbrooke's Hospital, Cambridge · Velindre Cancer Centre, Cardiff · Cardiff Children's Hospital, Cardiff · Western General Hospital, Edinburgh · Royal Hospital for Children Glasgow, Glasgow · The Beatson Hospital, Glasgow · Leicester Royal Infirmary, Leicester · Alder Hey Hospital, Liverpool · Guy's Hospital, London · University College London Hospital, London · Great Ormond Street Hospital, London · The Christie Hospital, Manchester · Royal Manchester Children's Hospital, Manchester · Clatterbridge Cancer Centre, Metropolitan Borough of Wirral · Great North Children's Hospital, Newcastle · Freeman Hospital, Newcastle · John Radcliffe Hospital, Oxford · Churchill Hospital, Oxford · Weston Park Hospital, Sheffield · Sheffield's Children's Hospital, Sheffield · Southampton General Hospital, Southampton · The Royal Marsden Hospital, Sutton

  Registry updated 2025-11-24

• NCT06988475

  DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

  Trial Treatment · Phase 2/3 · Cancer Research UK

  Belfast City Hospital, Belfast · University Hospital Birmingham, Birmingham · Bristol Haematology and Oncology Centre, Bristol · Addenbrooke's Hospital, Cambridge · Velindre Cancer Centre, Cardiff · Western General Hospital, Edinburgh · The Beatson Hospital, Glasgow · Leicester Royal Infirmary, Leicester · Guy's Hospital, London · University College London Hospital, London · The Christie Hospital, Manchester · Clatterbridge Cancer Centre, Metropolitan Borough of Wirral · Freeman Hospital, Newcastle · Churchill Hospital, Oxford · Western Park Hospital, Sheffield · Southampton General Hospital, Southampton · Royal Marsden Hospital, Sutton

  Registry updated 2025-11-24

• NCT04221035

  High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

  Trial Treatment · Phase 3 · Gustave Roussy, Cancer Campus, Grand Paris

  Royal Aberdeen Children's Hospital, Aberdeen · Royal Belfast Hospital for Sick Children, Belfast · University Hospitals Birmingham Queen Elisabeth Hospital(UHB), Birmingham · Birmingham Children's Hospital, Birmingham · University Hospitals Bristol and Weston NHS Foundation Trust, Bristol · Addenbrookes Hospital, Cambridge, Cambridge · Noah's Ark Children's Hospital for Wales, Cardiff, Cardiff · Royal Hospital for Sick Children - Edinburgh, Edinburgh · Royal Hospital for Children Glasgow, Glasgow · Leeds General Infirmary, Leeds · Alder Hey Children's Hospital, Liverpool, Liverpool · Great Ormond Street Hospital - London, London · Royal Manchester Children's Hospital, Manchester · Royal Victoria Infirmary, Newcastle, Newcastle · Nottingham Children's Hospital, Nottingham · Sheffield Children's Hospital, Sheffield · Southampton General Hospital, Southampton · Royal Marsden Hospital, Sutton

  Registry updated 2025-06-26

All Neuroblastoma trials and the map

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