Prostate cancer: open trials in Brazil

• NCT06136624

  Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Hospital Mario Penna ( Site 0309), Belo Horizonte · Hospital Felicio Rocho ( Site 0317), Belo Horizonte · Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0308), Bragança Paulista · Hospital Universitário Evangélico Mackenzie-Centro de Oncologia Mackenzie ( Site 0314), Curitiba · Clínica de Neoplasias Litoral ( Site 0305), Itajaí · Obras Sociais Irma Dulce ( Site 0302), Salvador · A. C. Camargo Cancer Center ( Site 0310), São Paulo · Hospital Santa Rita de Cassia-Centro de Pesquisa Clínica ( Site 0320), Vitória

  Registry updated 2026-11-05

• NCT07164443

  A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

  Trial Treatment · Phase 3 · Janssen Research & Development, LLC

  Grupo ELORA Centro de Pesquisa e Ensino em Saude de Santa Catarina, Florianópolis · Instituto Joinvilense de Hematologia e Oncologia Ltda Centro de Hematologia e Oncologia, Joinville · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Moinhos de Vento, Porto Alegre · Fundacao Antonio Prudente A C Camargo Cancer Center, São Paulo

  Registry updated 2026-11-03

• NCT07225946

  A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

  Trial Treatment · Phase 3 · Janssen Research & Development, LLC

  NAIC Nair Antunes Instituto do Cancer, Bauru · Liga Norte Riograndense Contra o Cancer, Natal · Hospital Ana Nery Santa Cruz do Sul, Santa Cruz do Sul · CEPHO Centro de Estudos e Pesquisa de Hematologia e Oncologia, Santo André · Hospital Samaritano de Sao Paulo, São Paulo

  Registry updated 2026-11-03

• NCT06629779

  A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

  Trial Treatment · Phase 3 · Pfizer

  Fundação Pio XII - Hospital de Câncer de Barretos, Barretos · Hospital Sírio-Libanês, Brasília · Hospital São Carlos, Fortaleza · Oncocentro Oncologia, Fortaleza · Instituto D'Or de Pesquisa e Ensino, Fortaleza · Crio - Centro Regional Integrado de Oncologia, Fortaleza · Oncocentro Servico Medicos e Hospitalares Ltda, Fortaleza · Liga Norte Riograndense Contra o Cancer, Natal · MedPlex Eixo Norte, Porto Alegre · Hospital Nossa Senhora da Conceição, Porto Alegre · Hospital Sao Lucas da PUCRS, Porto Alegre · Clinica Amo - Rio Vermelho, Salvador · Instituto D'Or de Pesquisa e Ensino (IDOR) - Filial Salvador, Salvador · CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia, Santo André · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto · IBCC - Núcleo de Pesquisa e Ensino, São Paulo · Instituto do Cancer Arnaldo Vieira de Carvalho, São Paulo · Hospital Alemão Oswaldo Cruz, São Paulo

  Registry updated 2026-10-30

• NCT06925737

  A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Hospital Mario Penna ( Site 0179), Belo Horizonte · Hospital Universitário Evangélico Mackenzie ( Site 0181), Curitiba · Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0184), Porto Alegre · Hospital de Base de São José do Rio Preto ( Site 0176), São José do Rio Preto · IPITEC ( Site 0189), São Paulo · IBCC - Núcleo de Pesquisa e Ensino ( Site 0183), São Paulo

  Registry updated 2026-10-30

• NCT07181161

  Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

  Trial Treatment · Phase 1/2 · AstraZeneca

  Barretos · Porto Alegre · São Paulo

  Registry updated 2026-10-22

• NCT05939414

  An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

  Trial Treatment · Phase 3 · Novartis Pharmaceuticals

  São Paulo

  Registry updated 2026-10-21

• NCT06136650

  A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Hospital Mario Penna ( Site 0264), Belo Horizonte · Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0251), Bragança Paulista · ICTRIALS Pesquisa e Desenvolvimento ( Site 0274), Curitiba · Hospital Universitário Evangélico Mackenzie ( Site 0252), Curitiba · CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA ( Site 0256), Fortaleza · Clínica de Neoplasias Litoral ( Site 0269), Itajaí · Hospital São Lucas da PUCRS ( Site 0270), Porto Alegre · Obras Sociais Irma Dulce ( Site 0255), Salvador · Hospital de Base de São José do Rio Preto ( Site 0275), São José do Rio Preto · Hospital São Domingos ( Site 0258), São Luís · Hospital Paulistano ( Site 0259), São Paulo · Instituto do Câncer Brasil - Unidade Taubaté ( Site 0263), Taubaté · Universidade Federal do Triangulo Mineiro - Hospital de Clinicas ( Site 0262), Uberaba · Hospital Santa Rita de Cassia ( Site 0271), Vitória

  Registry updated 2026-10-20

• NCT07611110

  AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  Trial Treatment · Phase 3 · AstraZeneca

  São Paulo

  Registry updated 2026-10-19

• NCT06855277

  Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  Trial Treatment · Phase 3 · Novartis Pharmaceuticals

  São Paulo

  Registry updated 2026-10-15

• NCT07711002

  Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

  Trial Treatment · Phase 3 · AstraZeneca

  Barretos · Brasília · Natal · Porto Alegre · São Caetano do Sul · São Paulo

  Registry updated 2026-10-15

• NCT06952803

  A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  Trial Treatment · Phase 3 · AstraZeneca

  Barretos · Cachoeiro de Itapemirim · Curitiba · Jaú · Londrina · Pelotas · Porto Alegre · Recife · Rio de Janeiro · Salvador · São Paulo

  Registry updated 2026-10-14

• NCT07028853

  This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

  Trial Treatment · Phase 3 · Pfizer

  Hospital Erasto Gaertner, Curitiba · Crio - Centro Regional Integrado de Oncologia, Fortaleza · ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijuí · Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa, Porto Alegre · CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia, Santo André · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto · Hospital Alemão Oswaldo Cruz, São Paulo · Instituto do Cancer Arnaldo Vieira de Carvalho, São Paulo · IBCC - Núcleo de Pesquisa e Ensino, São Paulo · BP - A Beneficência Portuguesa de São Paulo, São Paulo · Centro de Estudos e Pesquisas Oncologia de Sorocaba (CEPOS), Sorocaba

  Registry updated 2026-10-14

• NCT06863272

  A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

  Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC

  Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0268), Bragança Paulista · Liga Norte Riograndense Contra o Câncer ( Site 0271), Natal · Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0270), Porto Alegre · Hospital Moinhos de Vento ( Site 0278), Porto Alegre · Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) ( Site 0273), Ribeirão Preto · Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 0263), São José do Rio Preto · IBCC - Instituto Brasileiro de Controle do Câncer ( Site 0269), São Paulo · IPITEC ( Site 0275), São Paulo · Hospital Alemao Oswaldo Cruz ( Site 0279), São Paulo

  Registry updated 2026-10-09

• NCT07287150

  A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

  Trial Treatment · Phase 2 · Hoffmann-La Roche

  Irmandade Da Santa Casa de Misericordia de Porto Alegre, Porto Alegre · Instituto Nacional de Câncer - INCA, Rio de Janeiro · CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia, Santo André · Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base - PPDS, São José do Rio Preto · Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp, São Paulo

  Registry updated 2026-10-08

• NCT07190300

  TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

  Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals

  Porto Alegre

  Registry updated 2026-09-29

• NCT06780670

  Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

  Trial Treatment · Phase 2/3 · Novartis Pharmaceuticals

  São Paulo

  Registry updated 2026-09-22

• NCT07316686

  Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate Adenocarcinoma

  Trial Treatment · Phase 1 · Instituto do Cancer do Estado de São Paulo

  Instituto do Cancer do Estado de Sao Paulo - ICESP, São Paulo

  Registry updated 2026-08-25

• NCT07463092

  Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation Therapy

  Trial Treatment · University of Sao Paulo

  School of Physical Education and Sport - USP, São Paulo

  Registry updated 2026-06-11

• NCT03151629

  International Registry for Men With Advanced Prostate Cancer (IRONMAN)

  Research · Prostate Cancer Clinical Trials Consortium

  Hospital Beneficência Portuguesa, Bela Vista · Tacchini Hospital, Bento Gonçalves · Instituto do Câncer e Transplante, Curitiba · Centro de Pesquisa em Oncologia, Porto Alegre · Instituto Câncer do Estado de São Paulo, São Paulo · Centro Paulista de Oncologia, São Paulo

  Registry updated 2026-05-22

• NCT07560215

  PROMET-BR - Molecular Profiling of Metastatic Prostate Cancer: a Brazilian Cohort

  Research · AstraZeneca

  São Paulo

  Registry updated 2026-05-01

• NCT07432360

  Detecting Clinically Significant Prostate Cancer With Advanced MRI Protocols and Extensive Histopathology

  Research · Virdx, Inc.

  Instituto do Câncer do Estado de São Paulo, São Paulo

  Registry updated 2026-02-25

• NCT04704505

  Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)

  Trial Treatment · Phase 2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

  Moinhos de Vento Hospital, Porto Alegre

  Registry updated 2026-02-06

• NCT04373564

  Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

  Trial Treatment · Phase 4 · Guerbet

  Instituto Baía Sul de Ensino e Pesquisa (IEP), Florianópolis · Liga Norte-Rio-Grandense Contra o Câncer, Natal · Instituto Mederi de Pesquisa e Saude, Passo Fundo · Hospital Moinhos de Vento, Porto Alegre · CEMEC - Oncológica, São Bernardo do Campo · Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto · Albert Einstein Sociedade Beneficente Israelita Brasileira, São Paulo · CPCLIN - Centro de Pesquisas Clínicas Ltda., São Paulo · Hospital Santa Marta, Taguatinga

  Registry updated 2026-01-22

• NCT06787807

  Proteomic Analysis of Patients Undergoing Bariatric Surgery

  Trial Treatment · Universidade Federal de Pernambuco

  Hospital das clínicas da UFPE, Recife

  Registry updated 2025-01-22

All Prostate cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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