Prostate cancer: open trials in Germany

95 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT06136624
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · University Medical Center Hamburg-Eppendorf, Hamburg · University Hospital Jena KöR, Jena · Universitaetsklinikum Schleswig-Holstein, Lübeck · Universitaetsklinikum Muenster AöR, Muenster · Klinikum rechts der Isar der TU Muenchen AöR, Munich · HELIOS Kliniken Schwerin GmbH, Schwerin
Registry updated 2026-11-05
NCT06122584
Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
Trial Treatment · Phase 3 · ABX advanced biochemical compounds GmbH
Carl Gustav Carus Faculty of Medicine, TUD Dresden, Dresden · University Hospital Düsseldorf, Düsseldorf · St. Antonius Hospital, Gronau · University hospital Hamburg Eppendorf, Hamburg · University Hospital Leipzig, Leipzig · Klinikum rechts der Isar, TUM, München · University Hospital Munster, Münster · Universitätsmedizin Rostock, Rostock
Registry updated 2026-11-04
NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Trial Treatment · Phase 1 · Eli Lilly and Company
Universitaetsklinikum Erlangen, Erlangen · Universitaetsklinikum - Essen, Essen · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), München · LMU Klinikum Muenchen-Campus Grosshadern, München
Registry updated 2026-11-04
NCT07164443
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Staedtisches Klinikum Braunschweig gGmbH, Brunswick · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Urologicum Duisburg, Duisburg · Universitaetsklinikum Essen (AoR), Essen · Krankenhaus Nordwest GmbH, Frankfurt am Main · University Medical Center Hamburg-Eppendorf, Hamburg · National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg · Universitaet Muenster, Muenster · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen · Klinikum Nuernberg, Nuremberg
Registry updated 2026-11-03
NCT07225946
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Urologicum Duisburg, Duisburg · Universitaetsklinikum Essen (AoR), Essen · University Medical Center Hamburg-Eppendorf, Hamburg · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen
Registry updated 2026-11-03
NCT07888322
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
Research · Aristotle University Of Thessaloniki
Department of Neuroradiology, Charite, Berlin · Klinikum rechts der Isar, TUM, München
Registry updated 2026-11-02
NCT06629779
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Trial Treatment · Phase 3 · Pfizer
University Medical Center Hamburg-Eppendorf, Hamburg · Universitaet Muenster, Muenster · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-10-30
NCT06925737
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Charite Universitaetsmedizin Berlin KöR, Berlin · Studienzentrum Bayenthal Urologische Partnerschaft Köln, Cologne · Urologicum Duisburg, Duisburg · Goethe University Frankfurt, Frankfurt Am Main · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · LMU Klinikum Muenchen AöR, Munich · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen · Klinikum Nuernberg, Nuremberg · Logicuro GmbH, Potsdam · Klinikum Der Landeshauptstadt Stuttgart gKAöR, Stuttgart
Registry updated 2026-10-30
NCT07262619
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Trial Treatment · Phase 1/2 · Eikon Therapeutics
Helios Klinikum Berlin Buch, Berlin · DONAUISAR Klinikum, Deggendorf · Norddeutsches Studienzentrum fur Innovative Onkologie (NIO) Hamatologisch Onkologische Praxis Eppendorf (HOPE), Hamburg
Registry updated 2026-10-30
NCT07288359
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Essen · Jena
Registry updated 2026-10-29
2022-502285-24-00
Study to assess the safety and efficacy of the SpectraCure P18 System
Trial Treatment · Phase 1/2 · SpectraCure AB (publ)
Staedtisches Klinikum Braunschweig gGmbH, Brunswick
Registry updated 2026-10-27
2026-527906-19-00
New diagnostic pathway in primary diagnosis of clinically significant prostate cancer adding PSMA-PET to mpMRI
Trial Treatment · Phase 2 · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum)
Universitaetsklinikum Augsburg, Augsburg · TUM School Of Medicine And Health, Munich
Registry updated 2026-10-27
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Krankenhaus Nordwest GmbH, Frankfurt
Registry updated 2026-10-26
2025-524080-20-00
A clinical trial to learn about the effects of INR731 alone or with an androgen receptor pathway inhibitor (ARPI) in men with prostate cancer
Trial Treatment · Phase 1 · Novartis Pharma AG
Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-10-23
NCT07570979
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Dresden · Würzburg
Registry updated 2026-10-23
NCT05939414
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Universitaetsklinikum Aachen AöR, Aachen · Universitaetsklinikum Augsburg, Augsburg · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Universitaetsklinikum Bonn AöR, Bonn · University Hospital Cologne AöR, Cologne · Universitaetsklinikum Essen (AoR), Essen · Universitaetsklinikum Muenster AöR, Muenster · Klinikum der Universitaet Muenchen AöR, Munich · Rostock University Medical Center, Rostock
Registry updated 2026-10-21
NCT06136650
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
St. Marien-Krankenhaus GmbH, Bergisch Gladbach · Charite Universitaetsmedizin Berlin KöR, Berlin · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Urologicum Duisburg, Duisburg · Medical Center- University of Freiburg, Freiburg im Breisgau · Universitaetsmedizin Goettingen, Goettingen · National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg · Klinikum rechts der Isar der TU Muenchen AöR, Munich · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen · Universitaetsklinikum Regensburg AöR, Regensburg
Registry updated 2026-10-20
NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Trial Treatment · Phase 3 · Amgen
Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin · Universitaetsklinikum Bonn, Bonn · Universitaetsklinikum Dresden, Dresden · Uniklinikum Erlangen, Erlangen · Universitaetsklinikum - Essen, Essen · Universitaetsklinikum Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg, Heidelberg · Universitaetsklinikum Jena, Jena · Universitaetsklinikum Schleswig-Holstein - Kiel, Kiel · Universitaetsklinikum Ulm, Ulm · Universitaetsklinikum Wuerzburg, Würzburg
Registry updated 2026-10-20
NCT07344779
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Research · Bayer
Many Locations, Many Locations
Registry updated 2026-10-19
NCT07611110
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Trial Treatment · Phase 3 · AstraZeneca
Augsburg · Berlin · Bonn · Cologne · Dresden · Essen · Jena · Karlsruhe · München · Münster · Nuremberg · Rostock · Stuttgart · Tübingen · Würzburg
Registry updated 2026-10-19
2026-527059-25-00
A study of benfo‑oxythiamine added to Pluvicto® in adults with advanced prostate cancer whose disease is stable after two prior Pluvicto® cycles
Trial Treatment · Phase 1/2 · Benfovir AG
Universitaetsklinikum Essen (AoR), Essen · Universitatsklinikum Munster AöR, Muenster · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich
Registry updated 2026-10-16
NCT07365995
A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer
Trial Treatment · Phase 3 · BioNTech SE
Technische Universitaet Dresden, Dresden · Universitaetsklinikum Essen (AoR), Essen · Universitaetsklinikum Halle (Saale) AöR, Halle Saale · Asklepios Kliniken Hamburg GmbH, Hamburg · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaetsklinikum Magdeburg AöR, Magdeburg · Klinikum rechts der Isar der Technischen Universität München, München · Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR, Nuertingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-16
2026-525520-20-00
A study comparing Pluvicto® plus Standard of Care treatment with ADT and Nubeqa® vs. Standard of Care treatment with ADT and Nubeqa® in Patients with mHSPC
Trial Treatment · Phase 2 · Medical Center - University Of Freiburg
Medical Center- University of Freiburg, Freiburg im Breisgau
Registry updated 2026-10-15
NCT07226986
A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Dresden · Essen · München · Stuttgart
Registry updated 2026-10-15
NCT07711002
Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)
Trial Treatment · Phase 3 · AstraZeneca
St. Marien-Krankenhaus GmbH, Bergisch Gladbach · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Technische Universitaet Dresden, Dresden · Urologicum Duisburg, Duisburg · Universitaetsklinikum Essen (AoR), Essen · Goethe University Frankfurt, Frankfurt Am Main · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr, Herne · Heidelberg University, Mannheim · Urologie Neandertal, Mettmann · Universitaet Muenster, Muenster · LMU Klinikum Muenchen AöR, Munich · Klinikum Nuernberg, Nuremberg · Universitaet Rostock, Rostock · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-15

All Prostate cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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