Prostate cancer: open trials in United Kingdom

105 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07287150
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 2 · Hoffmann-La Roche
Velindre Cancer Centre, Cardiff · The Royal Marsden in Sutton, Surrey - Downs Rd, Sutton
Registry updated 2026-11-06
NCT06136624
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Addenbrooke's Hospital (Site 1605), Cambridge · The Beatson West of Scotland Cancer Centre (Site 1603), Glasgow · University College London Hospital (Site 1612), London · Charing Cross Hospital-Oncology Research (Site 1606), London · The Christie NHS Foundation Trust (Site 1608), Manchester · The Royal Cornwall Hospital (Site 1610), Truro
Registry updated 2026-11-05
NCT07567846
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer
Trial Treatment · Phase 1/2 · Genentech, Inc.
The Royal Marsden in Sutton, Surrey - Downs Rd, Sutton
Registry updated 2026-11-05
NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Trial Treatment · Phase 1 · Eli Lilly and Company
St. Bartholomew's Hospital, London · The Christie NHS Foundation Trust, Manchester
Registry updated 2026-11-04
NCT06788509
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
University Hospitals of Leicester NHS Trust, Leicester · St Bartholomews Hospital, London · University Hospitals Plymouth NHS Trust, Plymouth
Registry updated 2026-11-04
NCT07751133
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer
Trial Treatment · Phase 3 · University College, London
Calderdale and Huddersfield NHS Foundation Trust, Huddersfield · University Hospitals of Leicester NHS Trust, Huddersfield · The Christie NHS Foundation Trust, Manchester · The Royal Marsden NHS Foundation Trust, Sutton
Registry updated 2026-11-04
NCT05800665
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Trial Treatment · Phase 1 · Genentech, Inc.
Cambridge Clinical Research Centre, Cambridge · Leicester Royal Infirmary, Leicester · The Christie, Manchester · Royal Marsden Hospital - Surrey, Sutton
Registry updated 2026-11-03
NCT06800313
Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
Trial Treatment · Phase 1/2 · Janssen Research & Development, LLC
The Royal Marsden NHS Trust, Sutton
Registry updated 2026-11-03
NCT07082920
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
The Christie NHS Foundation Trust, Manchester · Royal Marsden Hospital (Sutton), Sutton
Registry updated 2026-11-03
NCT07164443
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
University Hospitals Birmingham NHS Foundation Trust, Birmingham · University College London Hospitals, London · The Christie NHS Foundation Trust - Christie Hospital, Manchester · Royal Marsden Hospital (Sutton), Sutton
Registry updated 2026-11-03
NCT07225946
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Velindre Cancer Centre, Cardiff · Beatson West of Scotland Cancer Centre, Glasgow · St Bartholomews Hospital, London · The Royal Marsden NHS Trust, London · The Newcastle upon Tyne Hospitals NHS Trust - Freeman Hospit, Newcastle upon Tyne · Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, Preston · Royal Marsden Hospital, Sutton
Registry updated 2026-11-03
NCT07319871
A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
The Christie NHS Foundation Trust - Christie Hospital, Manchester · Royal Marsden Hospital, Sutton
Registry updated 2026-11-03
NCT06629779
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Trial Treatment · Phase 3 · Pfizer
Royal Blackburn Hospital, Blackburn · Mid and South Essex NHS Foundation Trust, Chelmsford · Royal Derby Hospital, Derby · The Beatson West of Scotland Cancer Centre, Glasgow · The Clatterbridge Cancer Centre, Metropolitan Borough of Wirral
Registry updated 2026-10-30
NCT06925737
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Queen Elizabeth Hospital Birmingham (Site 0923), Birmingham · Addenbrooke's Hospital (Site 0915), Cambridge · Torbay Hospital (Site 0918), Devon · Royal Devon & Exeter Hospital (Site 0924), Exeter · St Bartholomew s Hospital (Site 0925), London · University College London Hospital (Site 0920), London · Mount Vernon Hospital (Site 0921), Northwood · Royal Marsden Hospital (Sutton) (Site 0922), Sutton
Registry updated 2026-10-30
NCT02705846
Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations
Research · Institute of Cancer Research, United Kingdom
Institute of Cancer Research and Royal Marsden Hospital, Sutton
Registry updated 2026-10-29
NCT04557449
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Trial Treatment · Phase 1/2 · Pfizer
Cancer Research UK Edinburgh Centre, Edinburgh · St. Bartholomew's Hospital, London · Sarah Cannon Research Institute UK, London · The Christie Hospital NHS Foundation Trust, Manchester
Registry updated 2026-10-28
NCT06242470
A Study of MGC026 in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1 · MacroGenics
Oxford University Hospitals NHS Foundation Trust, Oxford · The Royal Marsden NHS Foundation Trust, Sutton
Registry updated 2026-10-28
NCT02543905
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Research · Institute of Cancer Research, United Kingdom
Institute of Cancer Research and Royal Marsden Hospital, Sutton
Registry updated 2026-10-27
NCT05997615
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
Trial Treatment · Phase 1 · Astellas Pharma Global Development, Inc.
GB44003, Leicester · GB44001, London · GB44004, Newcastle
Registry updated 2026-10-27
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Addenbrooke's Hospital, Cambridge · University Hospital Coventry, Coventry · Barts Hospital, London · Royal Free Hospital, London · Nottingham City Hospital Campus, Nottingham
Registry updated 2026-10-26
NCT07181161
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Trial Treatment · Phase 1/2 · AstraZeneca
Cambridge · London · Plymouth · Sutton
Registry updated 2026-10-22
NCT05939414
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Bristol · Coventry · Guildford · London
Registry updated 2026-10-21
NCT06136650
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Addenbrooke's Hospital (Site 1426), Cambridge · Royal Derby Hospital (Site 1431), Derby · The Beatson West of Scotland Cancer Centre (Site 1428), Glasgow · Charing Cross Hospital (Site 1434), London · University College London Hospital (Site 1437), London · Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials (Site 1435), London · St. George's Hospital-Oncology (Site 1441), London · The Christie NHS Foundation Trust (Site 1436), Manchester · Mount Vernon Cancer Centre (Site 1440), Northwood · GenesisCare - Oxford (Site 1442), Oxford · Torbay Hospital (Site 1429), Torquay · The Royal Cornwall Hospital (Site 1430), Truro · GenesisCare - Windsor (Site 1443), Windsor
Registry updated 2026-10-20
NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Trial Treatment · Phase 3 · Amgen
Guys Hospital, London · Sarah Cannon Research Institute UK, London · Royal Marsden Hospital, Sutton
Registry updated 2026-10-20
NCT07344779
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Research · Bayer
Many Locations, Many Locations
Registry updated 2026-10-19

All Prostate cancer trials and the map

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