Prostate cancer: open trials in Italy

117 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT07287150
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 2 · Hoffmann-La Roche
Istituto Oncologico Veneto, Castelfranco Veneto · Istituto Nazionale dei Tumori, Milan · Ospedale San Raffaele S.r.l., Milan · IRCCS Istituto Nazionale Tumori Fondazione Pascale, Naples · I.F.O. Istituti Fisioterapici Ospitalieri, Rome
Registry updated 2026-11-06
NCT06136624
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l, Meldola · Ospedale San Raffaele S.r.l., Milan · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan
Registry updated 2026-11-05
NCT06122584
Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
Trial Treatment · Phase 3 · ABX advanced biochemical compounds GmbH
IRCCS - Istituto Romagnolo per lo Studio Dei Tumori, Dino Amadori, Meldola · IRCCS Ospedale Sacro Cuore Don Calabria, Verona
Registry updated 2026-11-04
NCT07610083
A Study Comparing Single-Port and Multi-Port Robot-Assisted Surgery in Patients With Prostate or Kidney (Renal) Cancer
Research · IRCCS San Raffaele
IRCCS Ospedale San Raffaele, Milan
Registry updated 2026-11-04
NCT07164443
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Istituto Oncologico Veneto, Castelfranco Veneto · Azienda Ospedaliero Universitaria Ospedali Riuniti, Foggia · Istituto Nazionale dei Tumori, Milan · Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · ARNAS Civico Di Cristina Benfratelli, Palermo · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-11-03
NCT07225946
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Azienda Ospedaliero-Universitaria Careggi, Florence · Azienda Sanitaria Locale Napoli 2 Nord, Frattamaggiore · Istituto Europeo di Oncologia s.r.l, Milan · Ospedale San Raffaele S.r.l., Milan · I.F.O. Istituti Fisioterapici Ospitalieri, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-11-03
NCT07888322
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
Research · Aristotle University Of Thessaloniki
Department of Advanced Biomedical Sciences, Naples
Registry updated 2026-11-02
NCT06629779
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Trial Treatment · Phase 3 · Pfizer
Azienda Socio-Sanitaria Territoriale di Cremona, Cremona · Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l, Meldola · Ospedale San Raffaele S.r.l., Milan · IRCCS Istituto Nazionale Tumori Fondazione Pascale, Naples · I.F.O. Istituti Fisioterapici Ospitalieri, Rome · Università Cattolica del Sacro Cuore, Rome · Humanitas Mirasole S.p.A., Rozzano · Azienda Ospedaliera S Maria Di Terni, Terni · Azienda Sanitaria Universitaria Integrata Del Trentino, Trento · Centro Ricerche Cliniche di Verona s.r.l., Verona
Registry updated 2026-10-30
NCT06925737
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Azienda Unita' Sanitaria Locale Toscana Sud Est, Arezzo · Azienda Ospedaliero Universitaria Ospedali Riuniti, Foggia · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan · I.F.O. Istituti Fisioterapici Ospitalieri, Rome · Humanitas Mirasole S.p.A., Rozzano · Azienda Ospedaliera Universitaria Senese, Siena · Azienda Ospedaliera S Maria Di Terni, Terni · Centro Ricerche Cliniche di Verona s.r.l., Verona
Registry updated 2026-10-30
NCT07262619
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Trial Treatment · Phase 1/2 · Eikon Therapeutics
Campus Bio-Medico di Rome University, Rome
Registry updated 2026-10-30
NCT07288359
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Milan
Registry updated 2026-10-29
NCT05936736
24 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer
Trial Treatment · IRCCS San Raffaele
San Raffaele Scientific Institute, Milan
Registry updated 2026-10-27
NCT06546267
Advanced Radiotherapy (ART) in Prostate Cancer (PROST-ART)
Research · IRCCS San Raffaele
IRCCS San Raffaele Scientific Institute, Milan
Registry updated 2026-10-27
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Humanitas Gavazzeni, Bergamo · IRCCS Ospedale Policlinico San Martino, Genova · AOU Federico II - Oncologia Clinica, Naples · Centro Ricerche Cliniche di Verona s.r.l., Verona
Registry updated 2026-10-26
2025-524080-20-00
A clinical trial to learn about the effects of INR731 alone or with an androgen receptor pathway inhibitor (ARPI) in men with prostate cancer
Trial Treatment · Phase 1 · Novartis Pharma AG
ASST Grande Ospedale Metropolitano Niguarda, Milan
Registry updated 2026-10-23
NCT07570979
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Milan
Registry updated 2026-10-23
2022-501894-37-00
"APalutamide and stEReotactic body radiation therapy for low burden metastatic hormone senSItive prostate cancer, a rANdomized trial -PERSIAN".
Trial Treatment · Phase 2 · Fondazione Radioterapia Oncologica Onlus
Azienda Sanitaria Locale Cn2 Alba-Bra, Alba · Azienda Sanitaria Usl Toscana Sud Est, Arezzo · Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · Istituto Di Candiolo Fondazione Del Piemonte Per Loncologia IRCCS, Candiolo · Careggi University Hospital, Florence · Azienda Ospedaliero Universitaria Ospedali Riuniti, Foggia · Azienda Sanitaria Locale Napoli 2 Nord, Frattamaggiore · IRCCS Ospedale Policlinico San Martino, Genoa · Ospedale Generale Provinciale Di Macerata, Macerata · Humanitas Istituto Clinico Catanese S.p.A., Misterbianco · Azienda Ospedaliero - Universitaria di Modena, Modena · Istituto Oncologico Veneto, Padova · Azienda Ospedaliero Universitaria Parma, Parma · Università degli Studi di Perugia, Perugia · Azienda USL IRCCS di Reggio Emilia, Reggio Emilia · Azienda Ospedaliero-Universitaria Sant Andre, Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Sapienza University Of Rome, Rome · Azienda Ospedaliera Universitaria Senese, Siena · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin · Azienda Sanitaria Universitaria Friuli Centrale, Udine
Registry updated 2026-10-22
NCT07181161
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Trial Treatment · Phase 1/2 · AstraZeneca
Ospedale San Raffaele S.r.l., Milan · Istituto Europeo di Oncologia s.r.l, Milan · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan · IRCCS Istituto Nazionale Tumori Fondazione Pascale, Naples · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-10-22
NCT05939414
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · University Hospital Of Ferrara, Ferrara · IRCCS Ospedale Policlinico San Martino, Genoa · European Institute Of Oncology S.r.l., Milan · IRCCS Ospedale Sacro Cuore Don Calabria, Negrar · Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Research Hospital, Rozzano
Registry updated 2026-10-21
NCT06136650
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Azienda Ospedaliera per l Emergenza Cannizzaro, Catania · Azienda Ospedaliero Universitaria Ospedali Riuniti, Foggia · Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l, Meldola · Ospedale San Raffaele S.r.l., Milan · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan · Azienda Ospedaliera S Maria Di Terni, Terni
Registry updated 2026-10-20
NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Trial Treatment · Phase 3 · Amgen
Azienda Ospedaliero Universitaria Ospedali Riuniti di Foggia, Foggia · Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan · IRCCS Ospedale San Raffaele, Milan · Azienda Ospedaliera Universitaria di Modena Policlinico, Modena · Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano · Ospedale Pederzoli Casa di Cura Privata, Peschiera del Garda · IRCCS Istituto Clinico Humanitas, Rozzano · Ospedale Santa Chiara Azienda Sanitaria Universitaria Integrata del Trentino, Trento
Registry updated 2026-10-20
2026-526915-12-00
PET-Guided Navigation with Electromagnetic Tracking during PSMA-RadioGuided Surgery: Innovative Bimodal Detection of Nodal Metastases in Prostate Cancer Patients
Trial Treatment · Phase 2 · Ospedale San Raffaele S.r.l.
Ospedale San Raffaele S.r.l., Milan
Registry updated 2026-10-19
NCT07344779
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Research · Bayer
Many Locations, Many Locations
Registry updated 2026-10-19
NCT07611110
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Trial Treatment · Phase 3 · AstraZeneca
Milan · Misterbianco · Naples · Negrar · Reggio Emilia · Rozzano
Registry updated 2026-10-19
NCT07879820
PSMA-Guided Surgery and Tissue-Resident T-Cell Profiling in Node-Positive Prostate Cancer
Trial Treatment · Niguarda Hospital
ASST Grande Ospedale Metropolitano Niguarda, Milan
Registry updated 2026-10-19

All Prostate cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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