Prostate cancer: open trials in South Africa

• NCT06629779

  A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

  Trial Treatment · Phase 3 · Pfizer

  Task Eden, George · Cancercare Langenhoven Drive Oncology Centre, Port Elizabeth · Wilgers Oncology Centre, Pretoria · Wits Clinical Research, Soweto

  Registry updated 2026-10-30

• NCT06925737

  A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Cancercare Rondebosch Oncology ( Site 0771), Cape Town · Wits Clinical Research ( Site 0776), Johannesburg · LIFE GROENKLOOF ( Site 0777), Pretoria · Curo Oncology Centre ( Site 0779), Pretoria · Wilgers Oncology Centre ( Site 0775), Pretoria

  Registry updated 2026-10-30

• NCT06136650

  A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Cape Town Oncology Trials ( Site 1233), Cape Town · Wits Clinical Research ( Site 1234), Johannesburg · CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE-Clinical Trials Unit ( Site 1230), Port Elizabeth · LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 1236), Pretoria · Wilgers Oncology Centre ( Site 1232), Pretoria · Curo Oncology. ( Site 1237), Pretoria

  Registry updated 2026-10-20

• NCT06879041

  A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

  Trial Treatment · Phase 1 · AstraZeneca

  CapeTown · Durban · Pretoria

  Registry updated 2026-10-16

• NCT03151629

  International Registry for Men With Advanced Prostate Cancer (IRONMAN)

  Research · Prostate Cancer Clinical Trials Consortium

  Groote Schuur Hospital, Cape Town · The Medical Oncology Centre of Rosebank, Johannesburg · Steve Biko Academic Hospital, Pretoria

  Registry updated 2026-05-22

• NCT04895839

  Predictors of Mental Health in Men With Prostate Cancer Undergoing a Patient Empowerment Program

  Trial Treatment · Gabriela Ilie

  Sefako Makgatho Health University, Ga-Rankuwa · Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg

  Registry updated 2026-03-18

All Prostate cancer trials and the map

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