Sarcoma: open trials in Australia

23 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Queensland Children's Hospital-Oncology & Haematology ( Site 1996), Brisbane · Royal Children's Hospital-Children's Cancer Centre ( Site 1994), Melbourne · Sydney Children's Hospital ( Site 1997), Randwick
Registry updated 2026-10-30
NCT07297979
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
Trial Treatment · Phase 1 · Amgen
Chris Obrien Lifehouse, Camperdown · Peter MacCallum Cancer Centre, Melbourne · Perth Childrens Hospital, Nedlands
Registry updated 2026-10-29
NCT06242470
A Study of MGC026 in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1 · MacroGenics
ICON Cancer Centre Wesley, Auchenflower · Austin Health- Olivia Newton John Cancer Center, Heidelberg · Icon Cancer Centre Kurralta Park, Kurralta Park
Registry updated 2026-10-28
NCT06345729
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Chris O'Brien Lifehouse ( Site 3000), Camperdown · Frankston Hospital ( Site 3002), Frankston · One Clinical Research ( Site 3001), Nedlands · Cancer Care Service Hervey Bay ( Site 3003), Urraween
Registry updated 2026-10-26
NCT07746141
A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations
Trial Treatment · Phase 1 · BeOne Medicines
Cabrini Hospital - Malvern, Malvern · Icon Cancer Centre South Brisbane, South Brisbane
Registry updated 2026-10-23
NCT04031677
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
Trial Treatment · Phase 3 · European Organisation for Research and Treatment of Cancer - EORTC
Chris O'Brian Life House - Chris O'Brien Lifehouse, Camperdown · Peter MacCallum Cancer Institute, Melbourne · Princess Alexandra Hospital - University Of Queensland, Woolloongabba
Registry updated 2026-10-07
NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 2 · Bayer
NSW Health - Blacktown Hospital, Blacktown · ICON Cancer Centre - Southport, Southport · Macquarie University Hospital - Oncology Department, Sydney
Registry updated 2026-10-02
NCT07713732
TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors
Trial Treatment · Phase 1 · Treeline Biosciences, Inc.
COBL Clinical Trials - Chris O'Brien Lifehouse, Camperdown · Cabrini Hospital - Malvern, Malvern · Linear Clinical Research, Nedlands
Registry updated 2026-10-01
NCT06884618
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
Trial Treatment · Phase 1 · Hoffmann-La Roche
St Vincent's Hospital Sydney, Darlinghurst · Peter MacCallum Cancer Center, Parkville
Registry updated 2026-09-28
NCT04094610
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.
Perth Childrens Hospital, Nedlands · Local Institution - 6104, Randwick · Children's Health Queensland Hospital and Health Service, South Brisbane · Local Institution - 6103, Westmead
Registry updated 2026-09-25
NCT07229313
A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 1 · Kivu Bioscience Inc.
Kivu Trial Site, Adelaide · Kivu Trial Site, Brisbane · Kivu Trial Site, Camperdown · Kivu Trial Site, Geelong · Kivu Trial Site, Sydney
Registry updated 2026-09-24
NCT05235165
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Trial Treatment · Phase 3 · Children's Oncology Group
Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · The Children's Hospital at Westmead, Westmead
Registry updated 2026-08-25
NCT05304585
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
Trial Treatment · Phase 3 · Children's Oncology Group
Perth Children's Hospital, Perth · Sydney Children's Hospital, Randwick · The Children's Hospital at Westmead, Westmead
Registry updated 2026-08-25
NCT06537596
89Zr-olaratumab Dosimetry in Participants With PDGFR Alpha Positive Solid Tumours and Soft Tissue Sarcoma
Trial Treatment · Phase 1 · Telix Pharmaceuticals (Innovations) Pty Ltd
Princess Alexandra Hospital 199 Ipswich Road, Woolloongabba, Brisbane · Precision Molecular Imaging & Theranostics Pty Ltd, Melbourne · GenesisCare Murdoch 100 Murdoch Drive, Murdoch WA, Perth
Registry updated 2026-08-14
NCT06910657
IDOV-Immune for Advanced Solid Tumors
Trial Treatment · Phase 1 · ViroMissile, Inc.
The Alfred Hospital, Melbourne · Westmead Hospital, Westmead
Registry updated 2026-08-05
NCT07377747
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Research · Australia and New Zealand Sarcoma Association
Chris O'Brien Lifehouse, Camperdown · Peter MacCallum Cancer Centre, Melbourne · Prince of Wales Hospital, Randwick
Registry updated 2026-07-15
NCT05653388
Metastatic Leiomyosarcoma Biomarker Protocol
Research · University of Michigan Rogel Cancer Center
Chris O'Brien Lifehouse, Camperdown · Peter MacCallum Cancer Centre, Melbourne
Registry updated 2026-06-24
NCT06789172
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
Trial Treatment · Phase 1 · Epkin
Linear Clinical Research, Perth · Chris O'Brien Lifehouse, Sydney
Registry updated 2026-06-11
NCT03093116
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.
Local Institution - 6103, Adelaide · Chris O'Brien Lifehouse, Camperdown · Local Institution - 3301, East Melbourne · Peter MacCallum Cancer Centre, Melbourne
Registry updated 2026-05-27
NCT01790152
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Research · Children's Oncology Group
Perth Children's Hospital, Perth · Princess Margaret Hospital for Children, Perth
Registry updated 2026-05-18
NCT04370587
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 1/2 · ImmVira Pharma Co. Ltd
Southern Oncology, Bedford Park · Peninsula & South Eastern Haematology and Oncology Group, Frankston · The Alfred, Melbourne
Registry updated 2025-10-08
NCT04625907
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
Trial Treatment · Phase 1/2 · University of Birmingham
Queensland Children's Hospital, Brisbane · Chris O'Brien Lifehouse, Camperdown · Monash Children's Hospital, Clayton · Peter MacCallum Cancer Centre, Melbourne · Royal Childrens Hospital Melbourne, Melbourne · John Hunter Children's Hospital, New Lambton Heights · Perth Children's Hospital, Perth · Sydney Children's Hospital, Sydney · The Childrens Hospital At Westmead, Sydney · Westmead Hospital, Westmead · Princess Alexandra Hospital, Woolloongabba
Registry updated 2024-05-23
NCT03838718
REtroperitoneal SArcoma Registry: an International Prospective Initiative
Research · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Peter MacCallum Cancer Center, Melbourne
Registry updated 2019-02-12

All Sarcoma trials and the map

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