Systemic sclerosis (scleroderma): open trials in Canada

• NCT07085104

  A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

  Trial Treatment · Phase 1 · Allogene Therapeutics

  Hôpital Maisonneuve-Rosemont, Montreal

  Registry updated 2026-11-02

• NCT03816345

  Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

  Trial Treatment · Phase 1 · National Cancer Institute (NCI)

  University Health Network, Princess Margaret Hospital, Toronto

  Registry updated 2026-10-05

• NCT04986605

  Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis

  Trial Treatment · Phase 2 · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

  Rheumatology Clinic, St. Joseph's Health Care, London

  Registry updated 2026-10-01

• NCT06256575

  Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

  Trial Treatment · Primus Pharmaceuticals

  University Of Calgary, Calgary · Dalhousie University, Halifax · Saint Joseph Health Care Centre, London · The Ottawa Hospital, Ottawa · Mount Sinai Health System, Toronto

  Registry updated 2026-09-11

• NCT03800017

  Skeletal Muscle Function in Interstitial Lung Disease

  Trial Treatment · University of British Columbia

  St. Paul's Hospital, Vancouver

  Registry updated 2026-05-15

• NCT06847750

  Elastography Ultrasound in Localized Scleroderma (Morphea) Study

  Research · The Hospital for Sick Children

  The Hospital for Sick Children, Toronto

  Registry updated 2026-04-29

• NCT04356287

  Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis

  Trial Treatment · Phase 1/2 · Marie Hudson, MD

  Sir Mortimer B Davis - Jewish General Hospital, Montreal

  Registry updated 2026-02-03

All Systemic sclerosis (scleroderma) trials and the map

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