Type 1 diabetes: open trials in Canada

51 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT07222137
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Trial Treatment · Phase 3 · Eli Lilly and Company
Alberta Children's Hospital, Calgary · Alberta Diabetes Institute, Edmonton · BC Diabetes Office, Vancouver
Registry updated 2026-11-04
NCT07222332
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Trial Treatment · Phase 3 · Eli Lilly and Company
Alberta Children's Hospital, Calgary · CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi · Alberta Diabetes Institute, Edmonton · St. Joseph's Health Care, London · Centricity Research Ottawa LMC Endocrinology, Ottawa · CHUL et Centre mère-enfant Soleil, Québec · BC Diabetes Office, Vancouver
Registry updated 2026-11-04
NCT07784725
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Brampton · Calgary · Guelph · Hamilton · Mississauga · Moncton · Montreal · New Westminster · North York · Québec · Saint-Charles-Borromée · Scarborough Village · Sherbrooke · Stoney Creek · Stouffville · Surrey · Toronto · Truro · Victoria
Registry updated 2026-10-30
NCT07891156
Lean Mass Changes With Semaglutide in Adults With Type 1 Diabetes and Overweight/Obesity.
Trial Treatment · Phase 2/3 · McGill University Health Centre/Research Institute of the McGill University Health Centre
Research Institute of the McGill University Health Centre Royal Victoria Hospital, Montreal
Registry updated 2026-10-23
NCT07088068
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Trial Treatment · Phase 3 · Sanofi
Calgary · Halifax · Ottawa · Vancouver
Registry updated 2026-10-13
NCT07348432
The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes
Research · McGill University
McGill University, Montreal
Registry updated 2026-10-09
NCT07831798
VV-14300 for the Treatment of Type 1 Diabetes
Trial Treatment · Phase 1/2 · Kriya Therapeutics, Inc.
Toronto
Registry updated 2026-10-05
NCT07851662
Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes
Trial Treatment · Institut de Recherches Cliniques de Montreal
Alberta Diabetes Institute, Edmonton · McMaster University, Hamilton · Institut de Recherches Cliniques de Montreal, Montreal
Registry updated 2026-10-01
NCT07564414
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Trial Treatment · Phase 3 · Novo Nordisk A/S
Centricity Research Brampton Endocrinology, Brampton · C-Health Partners, Calgary · Apex Trials, Guelph · Nova Scotia Hlth Halifax, Halifax · Hamilton Medical Research Group, Hamilton · Premier Clinical Trial Research Network (PCTRN), Hamilton · Wharton Medical Clinic Clinical Trials (Hamilton), Hamilton · Kelowna Health and Memory Centre Ltd., Kelowna · Medical Arts Health Research Group_Kelowna, Kelowna · Milestone Research, London · G.A. Research Associates, Ltd., Moncton · Centre Medical Acadie, Montreal · Centricity Res Pointe-Claire, Pointe-Claire · Diex Recherche Québec, Québec · Alpha Recherche Clinique - Lebourgneuf, Québec · Bluewater Clin Res Group Inc, Sarnia · Hilltop Medical Clinic, Surrey · Ocean West Research Clinic, Surrey · Care Access - Cape Breton, Sydney · Diabetes Heart Research Centre, Toronto · Dr. M.B. Jones Inc, Victoria
Registry updated 2026-09-30
NCT07776509
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Calgary · Guelph · Hamilton · Joliette · Montreal · Stouffville · Surrey · Toronto · Vancouver
Registry updated 2026-09-25
NCT07142252
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
Trial Treatment · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of British Columbia, Vancouver
Registry updated 2026-09-08
NCT04786262
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Trial Treatment · Phase 3 · Vertex Pharmaceuticals Incorporated
University of Alberta Edmonton, Edmonton · McGill University Health Centre, Montreal · Toronto General Hospital (TGH), Toronto · Vancouver General Hospital, Vancouver
Registry updated 2026-09-01
NCT07797335
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Trial Treatment · Phase 3 · Novo Nordisk A/S
Centricity Research Calgary Endocrinology, Calgary · University of Alberta Edmonton, Edmonton · Medical Arts Health Research Group_Kelowna_0, Kelowna · Kelowna Health and Memory Centre Ltd., Kelowna · CARe Clinic Ltd., Red Deer · Bluewater Clin Res Group Inc, Sarnia · Stouffville Medical Research Institute, Stouffville · Care Access - Cape Breton, Sydney · Centre de Medecine Metabolique de Lanaudiere, Terrebonne · Centricity Research Toronto, Toronto
Registry updated 2026-09-01
NCT07680673
ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion.
Trial Treatment · Phase 1 · Encellin
UHN, Toronto · Vancouver General Hospital, Vancouver
Registry updated 2026-08-20
NCT07758647
NO-Meal Announcement in Automated Insulin Delivery (Open-source and Commercial) Systems
Trial Treatment · Institut de Recherches Cliniques de Montreal
Institut de Recherches Cliniques de Montreal, Montreal
Registry updated 2026-08-11
NCT07712809
Intelligent Care Platform - Quasi-Experimental Trial
Trial Treatment · University of British Columbia
BC Children ' s Hospital, Vancouver
Registry updated 2026-07-22
NCT05188014
Exercise and the Menstrual Cycle in Type 1 Diabetes
Trial Treatment · University of Alberta
Alberta Diabetes Institute, Edmonton
Registry updated 2026-07-20
NCT07655076
Simultaneous Measurement and Responsive Treatment - Part 2
Trial Treatment · Early phase 1 · ClinSurge Research
ClinSurge Research, Toronto
Registry updated 2026-06-23
NCT05822609
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Trial Treatment · Phase 2 · University of Washington
Toronto General Hospital, University Health Network, Toronto
Registry updated 2026-06-02
NCT06296992
Type 1 Diabetes, Exercise and Mentoring Trial
Trial Treatment · University of Manitoba
Trillium Health Partners, Mississauga · the Children's Hospital Research Institute of Manitoba and the University of Manitoba, Winnipeg
Registry updated 2026-06-01
NCT07284511
A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar
Trial Treatment · Phase 2/3 · McGill University Health Centre/Research Institute of the McGill University Health Centre
Hygea Medical Clinic, Montreal · McGill University Health Centre, Montreal · Institut de Recherches Cliniques de Montreal, Montreal
Registry updated 2026-05-27
NCT06748963
Fasted Exercise Training in Type 1 Diabetes (FED-T1D)
Trial Treatment · University of Alberta
University of Alberta, Edmonton
Registry updated 2026-05-08
NCT04963777
Prebiotics in Patients With Type 1 Diabetes
Trial Treatment · University of Calgary
University Of Calgary, Calgary · University of Alberta, Edmonton · University of Saskatchewan, Saskatoon
Registry updated 2026-05-01
NCT05938712
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Trial Treatment · Phase 2 · University Health Network, Toronto
Toronto General Hospital, Toronto
Registry updated 2026-05-01
NCT06300047
Diabetes Transition Coordinator Study
Trial Treatment · University of Calgary
Alberta Children's Hospital, Calgary
Registry updated 2026-05-01

All Type 1 diabetes trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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