Clinical trials

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393 trials

NCT04667013
Not yet recruiting
A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of TBN
Phase 1 · - · no sites listed
Registry update: 11 Sept 2026
Fresh (updated 1 month ago)
NCT07838389
Not yet recruiting
Evaluation of Donor-Derived B Cell Infusions in Patients With Amyotrophic Lateral Sclerosis (ALS)
Phase 1 · US · 1 site
Registry update: 24 Sept 2026
Fresh (updated 1 month ago)
NCT06704347
Not yet recruiting
Safety Study of XT-150 in Participants With ALS
Phase 1 · US · 4 sites
Registry update: 29 Jul 2026
Fresh (updated 3 months ago)
NCT07906665
Not yet recruiting
A Study of Single Ascending Doses of NI112 in Adults With Amyotrophic Lateral Sclerosis (ALS)
Phase 1 · US · 3 sites
Registry update: 30 Oct 2026
Fresh (updated this month)
NCT07521930
Recruiting
Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)
Not applicable · US · 1 site
Registry update: 9 Oct 2026
Fresh (updated this month)
NCT07703462
Enrolling by invitation
Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALS
Phase 1/2 · US · 1 site
Registry update: 14 Jul 2026
Fresh (updated 3 months ago)
NCT02478450
Not yet recruiting
Study to Investigate the Safety of the Transplantation (by Injection) of Human Glial Restricted Progenitor Cells (hGRPs; Q-Cells®) Into Subjects With Amyotrophic Lateral Sclerosis (ALS)
Phase 1/2 · - · no sites listed
Registry update: 8 Jul 2026
Fresh (updated 3 months ago)
NCT07589764
Not yet recruiting
Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS
Phase 1 · US · 2 sites
Registry update: 4 Nov 2026
Fresh (updated this month)
NCT07871071
Recruiting
Brain-Computer Interface Communication Device for People With ALS
Not applicable · US · 1 site
Registry update: 16 Oct 2026
Fresh (updated this month)
2026-525574-19-00
Not yet recruiting
A Study of Long-Term Safety, Tolerability, and Clinical Outcomes of Intrathecally Administered LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis: A Multicenter, Open-Label, Long-Term Extension of Study J6I-MC-OWAA
Phase 1 · BE, DE, ES, NL · 7 sites
Registry update: 24 Sept 2026
Fresh (updated 1 month ago)
NCT07883590
Not yet recruiting
A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS).
Phase 1 · CA, US · 4 sites
Registry update: 20 Oct 2026
Fresh (updated this month)
NCT07823101
Recruiting
Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis
Not applicable · US · 1 site
Registry update: 28 Oct 2026
Fresh (updated this month)
NCT07698496
Not yet recruiting
Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS)
Not applicable · FR · 4 sites
Registry update: 13 Jul 2026
Fresh (updated 3 months ago)
NCT07855211
Recruiting
A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS)
Phase 1/2 · US · 2 sites
Registry update: 26 Oct 2026
Fresh (updated this month)
NCT05470478
Not yet recruiting
iBCI Optimization for Veterans With Paralysis
Not applicable · US · 1 site
Registry update: 27 Jul 2026
Fresh (updated 3 months ago)
NCT07325591
Not yet recruiting
Efficacy and Safety of Tazbentetol in ALS Participants
Phase 2/3 · - · no sites listed
Registry update: 10 Sept 2026
Fresh (updated 1 month ago)
NCT07875972
Not yet recruiting
Safety, Tolerability, and Pharmacodynamic Exploration of Orelabrutinib in Patients With Amyotrophic Lateral Sclerosis (ALS)
Phase 1 · - · no sites listed
Registry update: 15 Oct 2026
Fresh (updated this month)
NCT07834450
Not yet recruiting
Efficacy and Safety of Cyclophosphamide in Amyotrophic Lateral Sclerosis
Phase 2 · - · no sites listed
Registry update: 22 Sept 2026
Fresh (updated 1 month ago)
NCT07851714
Not yet recruiting
Metabolism and Nutrition in MND
Not applicable · GB · 1 site
Registry update: 1 Oct 2026
Fresh (updated 1 month ago)
NCT07813858
Not yet recruiting
Colchicine Effect on Amyotrophic Lateral Sclerosis Patients
Phase 2 · IT · 5 sites
Registry update: 10 Sept 2026
Fresh (updated 1 month ago)

Ordered by registry start date. Freshness and sponsorship never change the order.