Clinical trials

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163 trials

NCT07674277
Recruiting
Virtual Reality for SCD VOC
Not applicable · United States · 1 site
Registry update: 16 Oct 2026
NCT07282210
Recruiting
Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype
Phase 2 · Canada · 4 sites
Registry update: 2 Nov 2026
NCT07369024
Recruiting
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
Phase 2 · United States · 1 site
Registry update: 2 Sept 2026
NCT07562451
Recruiting
Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing
Not applicable · United States · 1 site
Registry update: 10 Sept 2026
NCT07616154
Recruiting
Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease
Phase 2 · United States · 1 site
Registry update: 23 Jul 2026
2025-523777-41-01
Recruiting
Morphine PCA vs Morphine and Lidocaine PCA for the treatment of vaso-occlusive crisis-related pain in sickle-cell anaemia patients: a prospective, randomized, double blind monocentric trial.
Phase 4 · Belgium · 1 site
Registry update: 26 Jan 2026
NCT07708350
Recruiting
Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease
Phase 1 · United States · 1 site
Registry update: 21 Oct 2026
NCT05377372
Recruiting
Early Life Exposures Among Children With Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 15 Jul 2026
NCT07566494
Recruiting
Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease
Phase 1 · United States · 1 site
Registry update: 21 Oct 2026
NCT07488520
Recruiting
Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire
Phase 4 · Côte d’Ivoire · 2 sites
Registry update: 5 Oct 2026
NCT07656415
Recruiting
A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)
Phase 3 · Belgium, France, Ireland, Italy, United States · 18 sites
Registry update: 28 Oct 2026
NCT07599176
Recruiting
Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors
Phase 1/2 · United States · 1 site
Registry update: 13 Oct 2026
2024-518437-28-00
Recruiting
Lidocaine for opioid sparing in vaso-occlusive crisis of Sickle Cell Disease
Phase 3 · France · 12 sites
Registry update: 3 Sept 2026
NCT07274254
Recruiting
Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease
Phase 3 · France, Guadeloupe · 12 sites
Registry update: 9 Sept 2026
NCT06725550
Recruiting
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
Not applicable · United States · 1 site
Registry update: 12 Aug 2026
NCT07252050
Recruiting
Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease
Phase 1/2 · United States · 4 sites
Registry update: 4 Jun 2026
NCT07392216
Recruiting
Functional Ovarian Reserve in Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 4 Jun 2026
NCT07708714
Recruiting
Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study
Phase 1/2 · Uganda · 1 site
Registry update: 16 Jul 2026
NCT07543289
Recruiting
Hydroxyurea Optimisation in Sickle Cell Disease
Not applicable · Nigeria · 1 site
Registry update: 27 Oct 2026
NCT07175051
Recruiting
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
Phase 2 · United States · 1 site
Registry update: 19 May 2026

Ordered by registry start date. Freshness and sponsorship never change the order.