Fatty liver disease (MASLD/MASH): what we know about treatments people ask about
How far testing has got for each one in Fatty liver disease (MASLD/MASH). This is what we know today, not advice.
How far testing has got
The step says how far testing has got, not that it works.
- Large trialsCurcumin (turmeric)Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsDichloroacetate (DCA)Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsFasting and fasting-mimicking dietTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsHigh-dose vitamin CTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsKetogenic dietTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsMelatoninTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsMetforminTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsStatinsTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Large trialsVitamin DTested in large studies that compare groups of patients. This says how far testing has got, not that it works.Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.
- Reports in peopleCannabis and cannabinoids (CBD, THC)Single case reports or observations in people. These cannot show whether it helps.Case reports, observational data, or pooled data without a reported benefit.
- Animal studies onlyAmygdalin (laetrile, "vitamin B17")Tested in animals only. Many things that work in animals do not work in people.In-vivo animal studies only.
- Animal studies onlyMistletoe extractTested in animals only. Many things that work in animals do not work in people.In-vivo animal studies only.
- Lab studies onlyIvermectinTested on cells in a lab dish only.In-vitro and cell-line studies only.
Not medical advice. Talk to the care team before changing treatment. Thinking of paying for it? Read this first