Melanoma: what we know about treatments people ask about

How far testing has got

The step says how far testing has got, not that it works.

• High-dose vitamin C

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 100 sources · 4 Nov 2026

  Large trials

• Hyperthermia

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 406 sources · 4 Nov 2026

  Large trials

• Melatonin

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 83 sources · 4 Nov 2026

  Large trials

• Metformin

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 86 sources · 4 Nov 2026

  Large trials

• Mistletoe extract

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 45 sources · 4 Nov 2026

  Large trials

• Statins

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 63 sources · 4 Nov 2026

  Large trials

• Vitamin D

  Tested in large studies that compare groups of patients. This says how far testing has got, not that it works.

  Phase 3 or randomised controlled trial on record. The rung shows the stage reached; the result is listed separately.

  Worked out by a fixed rule from 169 sources · 4 Nov 2026

  Large trials

• Fasting and fasting-mimicking diet

  First small studies in people, mainly to check safety and the dose.

  Phase 1, early Phase 1 or Phase 1/2 trial on record.

  Worked out by a fixed rule from 13 sources · 4 Nov 2026

  First trials in people

• Ketogenic diet

  First small studies in people, mainly to check safety and the dose.

  Phase 1, early Phase 1 or Phase 1/2 trial on record.

  Worked out by a fixed rule from 4 sources · 4 Nov 2026

  First trials in people

• Cannabis and cannabinoids (CBD, THC)

  Single case reports or observations in people. These cannot show whether it helps.

  Case reports, observational data, or pooled data without a reported benefit.

  Worked out by a fixed rule from 24 sources · 4 Nov 2026

  Reports in people

• Curcumin (turmeric)

  Single case reports or observations in people. These cannot show whether it helps.

  Case reports, observational data, or pooled data without a reported benefit.

  Worked out by a fixed rule from 161 sources · 4 Nov 2026

  Reports in people

• Dichloroacetate (DCA)

  Single case reports or observations in people. These cannot show whether it helps.

  Case reports, observational data, or pooled data without a reported benefit.

  Worked out by a fixed rule from 13 sources · 4 Nov 2026

  Reports in people

• Ivermectin

  Single case reports or observations in people. These cannot show whether it helps.

  Case reports, observational data, or pooled data without a reported benefit.

  Worked out by a fixed rule from 4 sources · 4 Nov 2026

  Reports in people

• Amygdalin (laetrile, "vitamin B17")

  Tested in animals only. Many things that work in animals do not work in people.

  In-vivo animal studies only.

  Worked out by a fixed rule from 3 sources · 4 Nov 2026

  Animal studies only

• Fenbendazole

  Tested in animals only. Many things that work in animals do not work in people.

  In-vivo animal studies only.

  Worked out by a fixed rule from 2 sources · 4 Nov 2026

  Animal studies only

• Mebendazole

  Tested in animals only. Many things that work in animals do not work in people.

  In-vivo animal studies only.

  Worked out by a fixed rule from 4 sources · 4 Nov 2026

  Animal studies only

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