What does science say about Probiotics and cancer (all types)?
- We don’t say yes or no. We show what has been studied.
- Working in a lab or in animals does not mean it works in people.
- Don’t stop or change your treatment without talking to your doctor.
What has been studied
- Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 10 Nov 2026 · Open the search at PubMed254studies
- Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 10 Nov 2026 · Open the search at PubMed483studies
- Studies in peoplePublished studies with human participants.Source: PubMed · as of 10 Nov 2026 · Open the search at PubMed327studies
- Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 32 · as of 9 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 0 · as of 9 Nov 2026 · Open the search at EU CTISBy phase:Phase 2 (12)No phase (12)Phase 3 (4)Phase 1 (2)Early Phase 1 (1)Phase 4 (1)By status:Recruiting (11)Completed (8)Not yet recruiting (7)Running, not recruiting (4)By invitation only (1)Withdrawn before start (1)Countries (10):China (11)United States (8)Canada (2)Mexico (2)Brazil (1)Spain (1)France (1)Indonesia (1)Italy (1)Taiwan (1)With a linked publication (results): 1 of 32The registries do not tell us here whether results were posted; a linked publication is shown instead.32trials
- Approved treatmentApproved by a medicines regulator for this disease.No
Cancer here means all 33 cancer types we cover.
Examples of what we found
The trials
Phase 2
Zanzalintinib and MO-03 for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy
Not yet recruiting · United States
ClinicalTrials.gov · NCT07578025No phase
Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.
Not yet recruiting · France
ClinicalTrials.gov · NCT07733817Phase 3
Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer
Recruiting · United States
ClinicalTrials.gov · NCT07383441No phase
Akkermansia Probiotics Plus Anti-PD-1 Monoclonal Antibody in MSS/pMMR Advanced Colorectal Cancer
Running, not recruiting · China
ClinicalTrials.gov · NCT06865521Phase 2
Effectiveness of Probiotics for the Prevention of Gastrointestinal Toxicity in Children With Leukemia
By invitation only · Mexico
ClinicalTrials.gov · NCT06560879Phase 2
Probiotics in Advanced Urothelial Carcinoma
Recruiting · China
ClinicalTrials.gov · NCT06904573Phase 1
CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer
Running, not recruiting · United States
ClinicalTrials.gov · NCT05122546Phase 2
Clinical Study of Neoadjuvant Chemotherapy and Immunotherapy Combined With Probiotics in Patients With Resectable NSCLC
Running, not recruiting · China
ClinicalTrials.gov · NCT04699721Phase 3
Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant
Running, not recruiting · Canada, United States
ClinicalTrials.gov · NCT03057054Phase 3
Lactobacillus Lozenges as Preventative Care in Low-grade Dysplasia
Withdrawn before start · United States
ClinicalTrials.gov · NCT05707702No phase
Dietary Fiber and Probiotics in Advanced Colorectal Cancer
Completed · China
ClinicalTrials.gov · NCT07194954Phase 1
CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer
Completed · United States
ClinicalTrials.gov · NCT03829111No phase
Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer
Completed · Mexico
ClinicalTrials.gov · NCT03994055
Thinking of paying for it? Read this first
- Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
- Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
- Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
- Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.
Not medical advice. Talk to the care team before changing treatment.