What does science say about Statins and cancer (all types)?
- We don’t say yes or no. We show what has been studied.
- Working in a lab or in animals does not mean it works in people.
- Don’t stop or change your treatment without talking to your doctor.
What has been studied
- Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 8 Nov 2026 · Open the search at PubMed400studies
- Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 8 Nov 2026 · Open the search at PubMed314studies
- Studies in peoplePublished studies with human participants.Source: PubMed · as of 8 Nov 2026 · Open the search at PubMed670studies
- Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 46 · as of 8 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 2 · as of 8 Nov 2026 · Open the search at EU CTISBy phase:Phase 2 (24)Phase 1 (7)Phase 3 (7)Phase 1/2 (3)Phase 4 (2)No phase (2)Early Phase 1 (2)Phase 2/3 (1)By status:Recruiting (21)Running, not recruiting (10)Not yet recruiting (8)Completed (8)Withdrawn before start (1)Countries (32):United States (24)China (10)Canada (5)Spain (5)Italy (4)Finland (3)France (3)United Kingdom (3)Australia (2)Israel (2)South Korea (2)Netherlands (2)Norway (2)Belgium (1)Brazil (1)Switzerland (1)Colombia (1)Czechia (1)Germany (1)Denmark (1)Estonia (1)Egypt (1)Indonesia (1)India (1)Japan (1)Moldova (1)Puerto Rico (1)Sweden (1)Singapore (1)Slovakia (1)With a linked publication (results): 5 of 48The registries do not tell us here whether results were posted; a linked publication is shown instead.48trials
- Approved treatmentApproved by a medicines regulator for this disease.No
Cancer here means all 33 cancer types we cover.
Examples of what we found
The trials
Phase 2
RESTAGE (REpurposing STAtins to Improve Outcomes in GastroEsophageal Cancer) Trial
Not yet recruiting · Canada
ClinicalTrials.gov · NCT07625930Phase 2
Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer
Not yet recruiting · United States
ClinicalTrials.gov · NCT07619365No phase
Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
Recruiting · United States
ClinicalTrials.gov · NCT07704918Phase 2
VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma
Recruiting · United States
ClinicalTrials.gov · NCT07831369Phase 2
Targeting Immune Modulation in High Grade Serous Carcinoma: Combined Effects of Chemotherapy and Atorvastatin
Not yet recruiting · United States
ClinicalTrials.gov · NCT07815704Phase 2
Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease
Recruiting · United States
ClinicalTrials.gov · NCT07685938Phase 1/2
PTC-Guided Atorvastatin Plus Axitinib and Toripalimab in Advanced RCC
Not yet recruiting · China
ClinicalTrials.gov · NCT07630363Phase 2/3
Neuroprotection of Memantine and Rosuvastatin
Not yet recruiting · Egypt
ClinicalTrials.gov · NCT07504198Phase 4
Statins to Prevent Immune Checkpoint Inhibitor-induced PRogression of AtherosLerosis
Not yet recruiting · Netherlands
ClinicalTrials.gov · NCT06785974Phase 2
Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA Melanoma
Running, not recruiting · United States
ClinicalTrials.gov · NCT06157099Phase 2
Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
Recruiting · United States
ClinicalTrials.gov · NCT04915183Phase 1/2
Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer
Recruiting · United States
ClinicalTrials.gov · NCT06030622Phase 3
Measuring Oncological Value of Exercise and Statin (MOVES)
Recruiting · Finland
EU CTIS · 2024-515109-24-00Phase 3
Measuring Oncological Value of Exercise and Statin
Recruiting · Finland
ClinicalTrials.gov · NCT05796973Phase 1
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
Recruiting · Australia, Canada, China, Germany, Spain, France, United Kingdom, Israel, Italy, Japan, South Korea, Netherlands, Norway, United States
ClinicalTrials.gov · NCT05614739Early Phase 1
Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma
Running, not recruiting · Canada
ClinicalTrials.gov · NCT04862260Phase 2
Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis
Running, not recruiting · United States
ClinicalTrials.gov · NCT04767984Phase 3
Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis
Running, not recruiting · United States
ClinicalTrials.gov · NCT03654053Phase 2
Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer
Running, not recruiting · United States
ClinicalTrials.gov · NCT03324425Phase 3
Impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy
Recruiting · Denmark, Estonia, Finland, Norway
EU CTIS · 2024-517854-91-00Phase 3
Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer
Recruiting · Switzerland, Czechia, France, Italy, Slovakia, Tunisia
ClinicalTrials.gov · NCT03819101Phase 1
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
Running, not recruiting · United States
ClinicalTrials.gov · NCT03889795Phase 1
A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies
Running, not recruiting · United States
ClinicalTrials.gov · NCT03560882Phase 3
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Recruiting · China, Spain, United Kingdom, Italy, United States
ClinicalTrials.gov · NCT03016819Phase 4
Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment
Running, not recruiting · Taiwan
ClinicalTrials.gov · NCT03024684No phase
A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
Running, not recruiting · Australia, Brazil, Canada, Colombia, Israel, India, Singapore, United States
ClinicalTrials.gov · NCT03127631Phase 2
Statin Addition to Chemotherapy for Advanced Pancreatic Cancer
Completed · China
ClinicalTrials.gov · NCT06241352Phase 3
Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer
Withdrawn before start · United Kingdom
ClinicalTrials.gov · NCT02201381Early Phase 1
Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer
Completed · United States
ClinicalTrials.gov · NCT04457089Phase 2
Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis
Completed · Puerto Rico, United States
ClinicalTrials.gov · NCT02968810Phase 1
Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC
Completed · Belgium, Spain, France, South Korea, United States
ClinicalTrials.gov · NCT02197234
Thinking of paying for it? Read this first
- Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
- Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
- Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
- Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.
Not medical advice. Talk to the care team before changing treatment.