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Vitamin C (incl. high-dose) & Myeloproliferative neoplasms

Checked 11 Nov 2026 · Myeloproliferative neoplasms

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Written based on 3 research studies on PubMed, searched on 11 Nov 2026.

The claim

Posts online say that vitamin C (incl. high-dose) helps with myeloproliferative neoplasms.

Where research stands

We found 3 published papers on vitamin C (incl. high-dose) and myeloproliferative neoplasms. They were published between 1954 and 2023. 1 of them is a study in people. None of them compared people who got it with a group that did not. None was a study in animals, and none was only in cells in the lab.

  • 1In people
  • 0In animals
  • 0Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Vitamin C (incl. high-dose) has been studied in people with myeloproliferative neoplasms, but not in randomised trials.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. A phase 2 trial of combination therapy with thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid (TADA) in patients with overlap myelodysplastic/myeloproliferative neoplasms (MDS/MPN) or primary myelofibrosis (PMF).2012 · Cancer · Study in people
  2. Clinical and molecular characteristics associated with Vitamin C deficiency in myeloid malignancies; real world data from a prospective cohort.2023 · Leuk Res · Other paper
  3. Alcoholic cirrhosis; complicated by polycythemia vera and then myelogenous leukemia and tolerance of large doses of vitamin C.1954 · Med Times · Other paper

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