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Polylaminin & Spinal Cord Injury

Checked 12 Nov 2026 · Spinal Cord Injury

Written from the studies on PubMed, searched on 12 Nov 2026. Every number below comes from a study listed under Sources. The text was written by AI from these studies; each sentence names the studies it comes from.

The claim

Posts say polylaminin, a lab-made form of a protein, can help people with spinal cord injury regain movement.

Where research stands

We found 3 published papers on polylaminin and spinal cord injury. They were published between 2010 and 2026. 1 of them is a study in people. In all, 8 people took part. None of them compared people who got it with a group that did not. 1 was a study in animals, and none was only in cells in the lab.

  • 1In people
  • 1In animals
  • 0Only in the lab

What the studies found

Trials in people

The one study in people was small and was done in Brazil. [1] It had 8 patients with a new, complete spinal cord injury. [1] All 8 got the treatment. There was no group to compare with. [1] The main aim was to check safety, not whether it works. [1] 6 of the 8 improved. But with so few people and no comparison group, we cannot tell if the treatment or natural recovery caused it. [1]

Other studies in people

A letter replied to this study. We have no text for it, so we cannot say what it argues. [2]

In animals

A study in rats found that polylaminin improved movement. [3] After a full cut of the spinal cord, the walking score rose from 4.2 to 8.8 in treated rats. [3] The authors also saw nerve fibres growing across the cut. [3] Results in rats do not always hold in people. [3]

Verdict

Unproven

The only test in people was very small and had no comparison group. [1] Rat results look promising, but they do not always hold in people, so the claim is unproven. [3]

Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Intramedullary injection of polymerized laminin in acute traumatic spinal cord injury: a first-in-human pilot study.2026 · Spinal Cord · Study in people
  2. Letter in response to "Intramedullary injection of polymerized laminin in acute traumatic spinal cord injury: a first-in-human pilot study1".2026 · Spinal Cord · Other paper
  3. Polylaminin, a polymeric form of laminin, promotes regeneration after spinal cord injury.2010 · FASEB J · In animals

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